Abstract: The present invention relates to a pharmaceutical composition comprising poorly soluble compounds such as BSC class II or IV kinase inhibitors, a process for the preparation thereof and its use in the treatment of diseases, in particular cancer, further particularly in non-small lung cancer.

Abstract: A method for adjusting an inertial sensor component using a calibration device. The calibration device includes a base device or the base device is connected to the calibration device. The method includes: in a first step for adjusting the inertial sensor component, its housing is positioned and/or aligned relative to the base device that is arranged in the calibration device and connected thereto, in a second step following the first step, the base device and the inertial sensor component are adjusted and/or calibrated using the calibration device by applying a defined acceleration in at least one spatial direction and/or a defined rotation rate in at least one spatial direction.

Abstract: The present invention relates to the production of antibodies in transgenic plants and screening of said antibodies for binding to antigens. The invention provides a method by which a large number of antibodies with variations in the multivariable regions are produced and screened for binding to antigens. The invention is particularly useful for the production of antibodies to antigens which may be present in different variants such as for example HIV-1 and A- or B-influenza viruses.

Abstract: A reporter system capable of giving rise to a directly monitorable phenotypic trait in a plant, in the presence of an outer stimulus such as for example a pollutant, is provided. The system optionally also has the ability to remediate soil. Genetically modified plants comprising said reporter system and optionally the remediation capability, a process for detection of soil pollution and optionally for bioremediating soil by employing said genetically modified plants, as well as the use of genetically modified plants for monitoring soil pollution and optionally for bioremediating soil are also provided.

Abstract: A device is used for generating error signals for regulating the optical alignment of two lightwaves in connection with coherent heterodyne reception and comprises a receiver device (2, 3, 4) arranged focused opposite a front face at the end of a lightwave fiber (7) in order to make possible the transmission of the received information lightwave through the lightwave fiber (7) to an optical waveguide coupler (6), which is connected via a further lightwave fiber (13) with a local laser (12) and via two further lightwave fibers (8, 9) with respectively one detector (10, 11) for generating at least one error signal (Sr). A piezoelectric deflection unit (5) acts on this front face of the lightwave fiber (7) located in the focusing area of the receiving device.

Abstract: A device for the control of the beam alignment in satellite laser communications systems has a digital signal processor (24), which has been inserted between an input interface (21) and an output interface (23), and to which a program memory (25) and a data memory (26) are separately connected, in which parameters are also stored, and which comprises sensors (171, 172, 173) and actuators (174, 175, 176) for aligning the laser beam with the counter station. The signal processor (24) contains an intermediate memory (240) for floating point and fixed point operations and further calculating units (241, 242, 243), as well as two access generators (244, 245). Highly flexible and very efficient control systems can be implemented by the employment of such a digital signal processor. By means of an adaptive control it is still possible to operate beam alignment systems at full performance levels, even after components have been degraded.