Abstract: A venous valve prosthesis for transporting a flow of body fluid in a vessel in a predetermined direction includes includes a hollow-cylindrical support structure. A skirt is connected to the support structure and forms a closed, circumferential jacket of the support structure. The prosthesis also includes a valve leaflet arrangement with a first valve leaflet and a second valve leaflet, each being connected to the skirt. A downstream edge of the first valve leaflet and a downstream edge of the second valve leaflet are opposite to each other and configured in such a manner that in a first state of the valve leaflet arrangement they form an opening for blood to flow through in the predetermined direction and in a second state of the valve leaflet arrangement the opening is closed and to prevent a backflow of blood in a direction opposite to the predetermined direction. A ratio of the inner diameter of the support structure to its length in the predetermined direction is at most 1.

Abstract: A method for producing a biological cover includes providing a first material having a main body in a cylindrical configuration with at least one fold in the first material. A second material is arranged within the at least one fold. The first material is a biological material. The first material with the arranged second material is pressed onto a counter member arranged outside the cylindrical configuration. A crosslinking agent is applied to the first material. A biological cover is formed of a biological material having a main body in a cylindrical configuration having a first cylinder diameter. There is at least one fold in the main body. The at least one fold is configured to at least partially unfold upon radial dilation of the biological material to permit enlargement of the cylindrical configuration to a second cylinder diameter.

Abstract: An intraluminal endoprosthesis has a biodegradable metallic supporting structure and a biodegradable sleeve surrounding the supporting structure. The sleeve includes fibres applied to the outer side of the supporting structure. The sleeve can be formed from fibres that each have a polymer core and a hydrogel casing. The sleeve can the sleeve be formed from a fibre mixture of polymer fibres and hydrogel fibres.

Abstract: An intraluminal endoprosthesis such as a stent has a metallic supporting structure and a sleeve surrounding the supporting structure. The sleeve can include fibres which are applied to an outer side of the supporting structure. The fibres each have a polymer core and a hydrogel casing connected thereto. The sleeve can also be formed from a fibre mixture of polymer and hydrogel fibres.

Abstract: A material includes nonwoven fibers and a surface modification that crosslinks the nonwoven fibers together. The surface modification can include chemical reactive groups. The reactive groups can be selected from diisocyanates, alcohols, epoxides, imides, amides, imines, amines, diacrylates, disiloxanes and disilazanes. A method of forming the material electrospins fiber material in the form of fibers into a nonwoven material. A surface modification is introduced to the fibers either by modifying the fiber material before the electrospinning or by modifying the fiber surface after the electrospinning. The fibers are crosslinked to form the crosslinked nonwoven material.

Abstract: A method for producing an intraluminal endoprosthesis. The method forms a sheath on a support structure of the endoprosthesis from polymer fibres. A polymer solution is dispensed from a nozzle by f electrospinning. The polymer solution includes at least one biodegradable polymer polymer and at least one additive. The additive is selected from the group consisting of: 1,3-dioxan-2-one, 1,4-dioxan-2-one, triethyl citrate, glycerol triacetate, n-butyryl tri-n-hexyl citrate, polyethylene glycol, L-? phosphatidylcholine.

Abstract: An intracardiac pacing system comprising a fixation element for fixing the intracardiac pacing system to body tissue is disclosed. The fixation element comprises a metallic material, and is at least partially coated with a metal-ion release inhibiting material. Also, a method for coating at least part of an intracardiac pacing system is disclosed.

Abstract: An anchoring device for anchoring an implantable medical device to tissue of a patient, wherein the anchoring device comprises at least one marker that is visible when using an imaging technique such as x-ray imaging.

Abstract: An anchoring device for anchoring an implantable medical device to tissue of a patient, wherein the anchoring device comprises: an annular member, a plurality of elongated tines connected to the annular member and protruding from the annular member, wherein the annular member comprises at least one stretchable first section that is stretchable along a peripheral direction of the annular member. Further, the invention relates to an implantable medical device (e.g., an implantable cardiac pacemaker) comprising such an anchoring device.

Abstract: An anchoring device for anchoring an implantable medical device to tissue of a patient, wherein the anchoring device comprises at least one marker that is visible when using an imaging technique such as x-ray imaging.

Abstract: An anchoring device for anchoring an implantable medical device to tissue of a patient, wherein the anchoring device comprises: an annular member, a plurality of elongated tines connected to the annular member and protruding from the annular member, wherein the annular member comprises at least one stretchable first section that is stretchable along a peripheral direction of the annular member. Further, the invention relates to an implantable medical device (e.g., an implantable cardiac pacemaker) comprising such an anchoring device.

Abstract: The invention relates to a method for the plasma treatment of an endoprosthesis having base body. The method includes inserting the base body into a vacuum chamber; executing a cleaning step with a plasma treatment of a surface of the base body that is to be coated; executing a treatment step in a plasma of the surface of the base body that is to be coated, wherein ions out of the plasma are implanted into an area of the base body that is close to the surface.

Abstract: An implant having a base body, comprised either entirely or in part of a biocorrodible metallic material wherein at least the parts of the base body having the biocorrodible metallic material are at least partially covered with a coating of a crosslinked CFx layer that is nonpolymerized and has an F/C ratio in the range of 0.5 to 1.5.

Abstract: A stent comprises a metallic, relatively radiolucent carrier structure and at least one marker element which includes comparatively radiopaque material. The radiopaque material is completely enclosed by a cover layer of a material other than the radiopaque material, the cover layer including metal or a metal compound. The stent may be used to treat a patient.

Abstract: The invention relates to an endovascular implant, which is at least largely biodegradable and whose in vivo degradation can be controlled. To achieve this, the implant comprises a tubular base body, open on its end faces and consisting of at least one biodegradable material, said base body having an in vivo, location-dependent first degradation characteristic D1(x), in addition to a coating that covers the base body completely or in sections and consists of a biodegradable material, said coating having an in vivo, location-dependent second degradation characteristic D2(x).

Abstract: An implant having a base body, comprised either entirely or in part of a biocorrodible metallic material wherein at least the parts of the base body having the biocorrodible metallic material are at least partially covered with a coating of a crosslinked CFx layer with an F/C ratio in the range of 0.5 to 1.5.

Abstract: A stent comprises a metallic, relatively radiolucent carrier structure and at least one marker element which includes comparatively radiopaque material. The radiopaque material is completely enclosed by a cover layer of a material other than the radiopaque material, the cover layer including metal or a metal compound. The stent may be used to treat a patient.

Abstract: The invention concerns an endovascular implant for the application of an active substance into the media 22 of a blood vessel and two processes for the production thereof. A base body 42 of the implant has at least in portion-wise manner at a surface 40 which is towards the blood vessel, a plurality of microdevices 10 for injection of the active substance. Each microdevice 10 includes on the one hand at least one microcannula 38 which is raised out of the surface 40 of the implant to such an extent that, when the implant bears against a wall 12 of the blood vessel in surface contact, the microcannula penetrates into the media 22 of the blood vessel, and on the other hand at least one active substance deposit 36 which is in communication with at least one microcannula 38.