Abstract: An analyzer (124) includes a quantifier (204) configured to quantify an amount of contrast material representing scar tissue created by ablation for tissue of interest in contrast enhanced imaging data and a recommender (210) configured to generate a signal indicative of a recommendation to further ablate the tissue of interest in response to the quantified amount of the contrast material not satisfying a pre-determined threshold. A method includes obtaining contrast enhanced image data indicative of scar tissue created by ablation of tissue of interest, quantifying an amount of contrast material for the scar tissue in the tissue of interest, and generating a signal indicative of a recommendation to further ablate the tissue of interest in response to the quantified amount of the contrast material not satisfying a pre-determined threshold.

Abstract: Various embodiments of the inventions of the present disclosure a systematic framework of matrices constructed as a basis for a centralized control of assigning imaging operators to operate imaging systems (11) in accordance with a plurality of scheduled imaging examinations.

Abstract: A method for alerting a user of a clinical pathways management system to a clinical pathway deviation, comprising: (i) providing a reference ontology comprising information about a plurality of clinical pathways; (ii) defining a domain ontology; (iii) converting the domain ontology to one or more graphical representations of clinical pathways; (iv) generating one or more deviation rules for the clinical pathways; (v) receiving information about one or more interventions relative to a patient being treated using a first clinical pathway; (vi) identifying, by comparing the received information about one or more interventions with the one or more deviation rules for the first clinical pathway, one or more deviations from the first clinical pathway; and (vii) alerting the user of the clinical pathways management system to the identified one or more deviations from the first clinical pathway.

Abstract: An imaging system (100) includes a radiation source (108) that emits radiation that traverses an examination region and imageable drug eluting beads in tissue of interest located therein, a spectral detector array (110) detects radiation traversing the examination region and generates a signal indicative thereof, spectral processing circuitry (117) that spectrally resolves the signal based on a plurality of thresholds (122), and a reconstructor (128) that generates spectral volumetric image data corresponding the imageable drug eluting beads based on the spectrally resolved signal.

Abstract: A method includes analyzing a spectral projection image of a portion of a subject, generating a value quantifying an amount of a target specific contrast material in a region of interest of the spectral projection image, and generating a signal indicative of a presence of the target in response to the value satisfying a predetermined threshold level.

Abstract: A method includes determining calibration factors for calibrating photon-counting detectors of a spectral imaging system by combining a heuristic calibration of the photon-counting detectors and an analytical calibration of the photon-counting detectors and generating a set of photon-counting calibration factors based on the combining of the a heuristic calibration and the analytical calibration. The photon-counting calibration factors, when applied to measured energy-resolved data from the photon-counting detectors of a spectral CT scan of a subject or object, mitigate spectral distortion caused by a radiation intensity profile shaper that filters a radiation beam of the spectral CT scan.

Abstract: A method includes obtaining first spectral image data, which includes at least a first component corresponding to a targeted first K-edge based contrast agent administered to a subject if a target of the targeted first K-edge based contrast agent is present in the subject, decomposing the first spectral image data into at least the first component, reconstructing the first component thereby generating a first image of the targeted first K-edge contrast agent, determining if the targeted first K-edge contrast agent is present in the first image, and generating a signal indicating the targeted first K-edge contrast agent is present in the first image in response to determining the targeted first K-edge contrast agent is present in the first image.

Abstract: A radio therapy apparatus (100) includes a tissue of interest tracker (124) that receives a first image of tissue of interest and a second later acquired spectral image of the tissue of interest and tracks a change in a geometry and/or location of the tissue of interest based at least on the first and second images and generates a signal indicative of the change. The second image is generated based on a first spectral signal corresponding to an output of an energy-resolving radiation sensitive detector array for a first predetermined energy range and a second spectral signal corresponding to an output of the energy-resolving radiation sensitive detector array for a second predetermined energy range and visually enhances scanned structure corresponding to the first or second signals while visually suppressing scanned structure corresponding to the other of the first or second signals. An adaptive planner (126) updates a radiotherapy treatment plan based on the signal.

Abstract: A method includes determining calibration factors for calibrating photon-counting detectors of a spectral imaging system by combining a heuristic calibration of the photon-counting detectors and an analytical calibration of the photon-counting detectors and generating a set of photon-counting calibration factors based on the combining of the a heuristic calibration and the analytical calibration. The photon-counting calibration factors, when applied to measured energy-resolved data from the photon-counting detectors of a spectral CT scan of a subject or object, mitigate spectral distortion caused by a radiation intensity profile shaper that filters a radiation beam of the spectral CT scan.

Abstract: A radio therapy apparatus (100) includes a tissue of interest tracker (124) that receives a first image of tissue of interest and a second later acquired spectral image of the tissue of interest and tracks a change in a geometry and/or location of the tissue of interest based at least on the first and second images and generates a signal indicative of the change. The second image is generated based on a first spectral signal corresponding to an output of an energy-resolving radiation sensitive detector array for a first predetermined energy range and a second spectral signal corresponding to an output of the energy-resolving radiation sensitive detector array for a second predetermined energy range and visually enhances scanned structure corresponding to the first or second signals while visually suppressing scanned structure corresponding to the other of the first or second signals. An adaptive planner (126) updates a radiotherapy treatment plan based on the signal.

Abstract: A method includes obtaining first spectral image data, which includes at least a first component corresponding to a targeted first K-edge based contrast agent administered to a subject if a target of the targeted first K-edge based contrast agent is present in the subject, decomposing the first spectral image data into at least the first component, reconstructing the first component thereby generating a first image of the targeted first K-edge contrast agent, determining if the targeted first K-edge contrast agent is present in the first image, and generating a signal indicating the targeted first K-edge contrast agent is present in the first image in response to determining the targeted first K-edge contrast agent is present in the first image.

Abstract: An imaging system (100) includes a radiation source (108) that emits radiation that traverses an examination region and imageable drug eluting beads in tissue of interest located therein, a spectral detector array (110) detects radiation traversing the examination region and generates a signal indicative thereof, spectral processing circuitry (117) that spectrally resolves the signal based on a plurality of thresholds (122), and a reconstructor (128) that generates spectral volumetric image data corresponding the imageable drug eluting beads based on the spectrally resolved signal.

Abstract: An analyzer (124) includes a quantifier (204) configured to quantify an amount of contrast material representing scar tissue created by ablation for tissue of interest in contrast enhanced imaging data and a recommender (210) configured to generate a signal indicative of a recommendation to further ablate the tissue of interest in response to the quantified amount of the contrast material not satisfying a pre-determined threshold. A method includes obtaining contrast enhanced image data indicative of scar tissue created by ablation of tissue of interest, quantifying an amount of contrast material for the scar tissue in the tissue of interest, and generating a signal indicative of a recommendation to further ablate the tissue of interest in response to the quantified amount of the contrast material not satisfying a pre-determined threshold.

Abstract: A method includes analyzing a spectral projection image of a portion of a subject, generating a value quantifying an amount of a target specific contrast material in a region of interest of the spectral projection image, and generating a signal indicative of a presence of the target in response to the value satisfying a predetermined threshold level.

Abstract: The invention relates to an imaging system for imaging a region of interest comprising a moving object, which moves less in small motion phases than in large motion phases. Detection values are provided and a small motion determination unit (15) determines the motion of the object in the region of interest in the small motion phases from the 5 detection values. A large motion determination unit (16) determines the motion of the object in the large motion phases from the determined motion of the object in the small motion phases. A reconstruction unit (17) reconstructs an image of the region of interest from the detection values, wherein the reconstruction unit (17) is adapted for performing a motion compensation using the determined motions in the small and large motion phases.

Abstract: The invention relates to an imaging system for imaging a region of interest comprising a moving object, which moves less in small motion phases than in large motion phases. Detection values are provided and a small motion determination unit (15) determines the motion of the object in the region of interest in the small motion phases from the 5 detection values. A large motion determination unit (16) determines the motion of the object in the large motion phases from the determined motion of the object in the small motion phases. A reconstruction unit (17) reconstructs an image of the region of interest from the detection values, wherein the reconstruction unit (17) is adapted for performing a motion compensation using the determined motions in the small and large motion phases.