Publication number: 20200222432
Abstract: Provided herein are methods of treating non-inflammatory lesions and symptoms thereof comprising administering to a subject in need thereof a therapeutically effective amount of (4S,4aS,5aR,12aS)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide or pharmaceutically acceptable salts thereof. In certain embodiments, a crystalline mono hydrochloride, mono mesylate, or mono sulfate salt of (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide is administered.
Type:
Application
Filed:
July 20, 2018
Publication date:
July 16, 2020
Inventors:
David BERK, Alexandre KAOUKHOV, Vilma SNIUKIENE, Carsten SCHMITZ