Abstract: The embodiments disclose a method including interpreting of APOP results for a series of drugs or combinations and creating a direct APOP assay of purified cells, creating suggested clinician decisions based on the direct APOP assay of purified cells results in choosing potential treatments each when combined with genomic changes identified by next generation testing of tumor DNA from purified cells, identifying nonequivalence of drugs in the APOP assay or other tests, identifying cannabinoid/CBD anti-tumor effects or immune-activity effects or enhancement of other drug anti-tumor effects in the APOP assay or other tests, and using a direct APOP assay of purified cells application for transmitting direct APOP assay data.

Abstract: The embodiments disclose a method including interpreting of APOP results for a series of drugs or combinations and creating a direct APOP assay of purified cells, creating suggested clinician decisions based on the direct APOP assay of purified cells results in choosing potential treatments each when combined with genomic changes identified by next generation testing of tumor DNA from purified cells, identifying nonequivalence of drugs in the APOP assay or other tests, identifying cannabinoid/CBD anti-tumor effects or immune-activity effects or enhancement of other drug anti-tumor effects in the APOP assay or other tests, and using a direct APOP assay of purified cells application for transmitting direct APOP assay data.

Abstract: Micellular particles such as small unilamellar vesicles of less than 2000 A° loaded with 111In are administered to BALB/c mice in which EMT6 tumors had been induced. Whole body scintographs of the mice to which either neutral or positively or negatively charged vesicles had been administered show a substantial quantity of the vesicle entrapped 111In localized in the tumor. Blocking of macrophages in the liver and spleen by first administering unlabeled, aminomannose substituted vesicles before administration of the labeled vesicles increases uptake of the 111In labeled vesicles in the tumor.

Abstract: A method is provided for delivering micellular particles containing chemotherapeutic agents and a marker to tumors within a body for the diagnosis and treatment of such tumors. The micellular particles are small, less than 2000 .ANG. and incorporate pure, neutral phospholipid molecules in their external surface. Enhanced delivery of the micellular particles containing marker and chemotherapeutic agents may be achieved by introducing an initial group of positively charged micellular particles to block the reticuloendothelial cells present in the body.

Abstract: Micellular particles such as small unilamellar vesicles of less than 2000 .ANG. loaded with .sup.111 In are administered to BALB/c mice in which EMT6 tumors had been induced. Whole body scintographs of the mice to which either neutral or positively or negatively charged vesicles had been administered show a substantial quantity of the vesicle entrapped .sup.111 In localized in the tumor. Blocking of macrophages in the liver and spleen by first administering unlabeled, aminomannose substituted vesicles before administration of the labeled vesicles increases uptake of the .sup.111 In labeled vesicles in the tumor.

Abstract: A method is provided for delivering micellular particles containing a radiolabelled marker to tumors within humans. The micellular particles are less than approximately 2000.ANG. and incorporate essentially chemically pure phospholipid molecules in their external surface. Human patients given intravenous injections of such radiolabelled micellular particles showed tumors imaged by such method, without developing symptoms related to the micellular particles.