Patents by Inventor Cary J. Reich
Cary J. Reich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200030142Abstract: An apparatus to treat a patient comprises a container to receive fluid of a device implanted in the eye. The fluid of the device can be analyzed to determine a component of the vitreous humor of the eye.Type: ApplicationFiled: August 14, 2019Publication date: January 30, 2020Inventors: Signe Erickson, Darren Doud, Eugene de Juan, JR., Yair Alster, Cary J. Reich, Kathleen Cogan Farinas
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Publication number: 20200004047Abstract: An eye covering such as a contact lens may comprise one or more structures to pump tear liquid under the covering such that the covering can remain in the eye and correct vision for an extended amount of time. In many embodiments, the covering comprises a material having fenestrations to draw tear liquid under the covering and an outer portion shaped to contact the conjunctiva over the sclera, such that when the eye closes pressure of one or more eyelids urges tear liquid through one or more fenestrations and under the outer portion shaped to contact the conjunctiva.Type: ApplicationFiled: September 3, 2019Publication date: January 2, 2020Inventors: EUGENE DE JUAN, CARY J. REICH, YAIR ALSTER, MATT CLARKE, KUANGMON ASHLEY TUAN, BRIAN LEVY
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Publication number: 20190353930Abstract: Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include an inner optic portion having a scaffold between an anterior portion and a posterior portion. The scaffold is characterized by a substantially uniform thickness formed from a material characterized by a modulus that his higher than the modulus of the peripheral portion. Openings within the scaffold are filled with a low modulus material. When applied to an eye, the lenses are configured to provide one or more lenticular volumes between the posterior surface of the lens and the cornea. The disclosure further relates to methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses.Type: ApplicationFiled: August 5, 2019Publication date: November 21, 2019Inventors: Eugene de Juan, JR., Cary J. Reich, Matt Clarke, Kuangmon Ashley Tuan, Raymond Lum, Jose D. Alejandro
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Publication number: 20190336335Abstract: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.Type: ApplicationFiled: April 17, 2019Publication date: November 7, 2019Inventors: Eugene de Juan, JR., Yair Alster, Kathleen Cogan Farinas, K. Angela Macfarlane, Cary J. Reich, Randolph E. Campbell, Darren Doud, Signe Erickson, Mike Barrett, David Batten, Christina Skieller, Greg Stine
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Patent number: 10456293Abstract: Disclosed is an ocular device including a first structure formed of a first material providing a first shape to the ocular device prior to positioning the ocular device on the surface of the eye, a second structure formed of a second, different material having a tubular structure and a lumen through which the first structure extends, and at least one therapeutic agent is dispersed within the second material of the second structure. The first shape of the ocular device conforms to a second, different shape after positioning the ocular device on the surface of the eye. Upon being removed from the eye, the ocular device retains the second shape or changes to a third shape different from both the first shape and the second shape. Related apparatus, systems and method are described.Type: GrantFiled: September 1, 2017Date of Patent: October 29, 2019Assignee: ForSight Vision5, Inc.Inventors: Anne Brody Rubin, Yair Alster, Cary J. Reich
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Patent number: 10398592Abstract: An apparatus to treat a patient comprises a container to receive fluid of a device implanted in the eye. The fluid of the device can be analyzed to determine a component of the vitreous humor of the eye.Type: GrantFiled: June 28, 2012Date of Patent: September 3, 2019Assignee: ForSight Vision4, Inc.Inventors: Signe Erickson, Darren Doud, Eugene de Juan, Jr., Yair Alster, Cary J. Reich, Kathleen Cogan Farinas
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Publication number: 20190231922Abstract: Described is a process for making a dry and stable hemostatic composition, said process comprising a) providing a first component comprising a dry preparation of a coagulation inducing agent, b) providing a second component comprising a dry preparation of a biocompatible polymer suitable for use in hemostasis, c) providing said first component and said second component in a combined form in a final container, c1) either by filling said first component and said second component into said final container so as to obtain a dry mixture in said final container, c2) or by providing said first component or said second component in said final container and adding said second component or said first component so as to obtain a combination of said first component with said second component in said final container, d) finishing the final container to a storable pharmaceutical device containing said first component and said second component in a combined form as a dry and stable hemostatic composition.Type: ApplicationFiled: February 11, 2019Publication date: August 1, 2019Inventors: Andreas Goessl, Atsushi Edward Osawa, Cary J. Reich
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Publication number: 20190223998Abstract: Disclosed is an accommodating intraocular lens device for treatment of an eye including a stabilization haptic (120) configured to be positioned within a region of an eye and a lens body having a sealed chamber containing a fixed volume of optical fluid. The lens body includes a shape changing membrane (145) configured to outwardly bow in a region surrounding the optical axis of the eye; a shape deformation membrane configured to undergo displacement relative to the first shape changing membrane; and a static element (150). An inner surface of the shape changing membrane, an inner surface of the shape deformation membrane and an inner surface of the static element collectively form the sealed chamber. The lens device also includes a force translation arm (115) having a first end configured to contact an outer surface of the shape deformation membrane of the lens body and a second end configured to engage a ciliary structure of the eye.Type: ApplicationFiled: April 1, 2019Publication date: July 25, 2019Inventors: Eugene de Juan, JR., Cary J. Reich, Hanson S. Gifford, III, Guy Oren, Matthew Clarke, Jose D. Alejandro
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Publication number: 20190142842Abstract: The present disclosure includes compositions of a semi-crystalline or crystalline pharmaceutically active agent dispersed in a polymer matrix, in which the active agent is less degraded and, therefore, has lower level of impurities. The present disclosure further includes a method of reducing or preventing physical and chemical degradation of a semi-crystalline or crystalline active agent pharmaceutically active agent dispersed in a polymer matrix. A method of preparation of the composition is also included in this disclosure.Type: ApplicationFiled: January 9, 2019Publication date: May 16, 2019Inventors: Logan Stark, Rachna Jain, Ravi Srinivasan, Cary J. Reich, Carlos Schuler
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Patent number: 10285805Abstract: Disclosed is an accommodating intraocular lens device for treatment of an eye including a stabilization haptic (120) configured to be positioned within a region of an eye and a lens body having a sealed chamber containing a fixed volume of optical fluid. The lens body includes a shape changing membrane (145) configured to outwardly bow in a region surrounding the optical axis of the eye; a shape deformation membrane configured to undergo displacement relative to the first shape changing membrane; and a static element (150). An inner surface of the shape changing membrane, an inner surface of the shape deformation membrane and an inner surface of the static element collectively form the sealed chamber. The lens device also includes a force translation arm (115) having a first end configured to contact an outer surface of the shape deformation membrane of the lens body and a second end configured to engage a ciliary structure of the eye.Type: GrantFiled: March 25, 2015Date of Patent: May 14, 2019Assignee: ForSight Labs, LLCInventors: Eugene de Juan, Jr., Cary J. Reich, Hanson S. Gifford, III, Guy Oren, Matthew Clarke, Jose D. Alejandro
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Patent number: 10265215Abstract: Methods and apparatus provide a therapeutic fluid to devices implanted in the body, for example to containers of devices implanted in the eye of a patient. The methods and apparatus may comprise an injector to increase an amount of therapeutic agent injected into the device implanted in the eye, or a structure to receive the therapeutic fluid within the device implanted in the eye, or combinations thereof. The device implanted in the eye may comprise a reservoir chamber having a fluid with a density different than the therapeutic fluid, and the apparatus can be adapted to at least partially separate the implanted device fluid from therapeutic fluid within the reservoir chamber to increase and amount of therapeutic fluid placed in the reservoir chamber.Type: GrantFiled: December 13, 2017Date of Patent: April 23, 2019Assignee: ForSight Vision4, Inc.Inventors: Eugene de Juan, Jr., Yair Alster, Kathleen Cogan Farinas, K. Angela Macfarlane, Cary J. Reich, Randolph E. Campbell, Darren Doud, Signe Erickson, Mike Barrett, David Batten, Christina Skieller, Greg Stine
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Publication number: 20190105198Abstract: A therapeutic system comprises an ocular insert placed on a region outside an optical zone of an eye. The ocular insert comprises two structures: a first skeletal structure and a second cushioning structure. The first structure functions as a skeletal frame which maintains positioning of the implant along the anterior portion of the eye and provides support to the second, cushioning structure. This first structure maintains the attachment of the therapeutic system to the anterior portion of the eye for at least thirty days. In some embodiments the first structure remains a constant size and shape, e.g. a ring shape, a ring with haptics, or a curvilinear ring that is confined to and restrainingly engages the inferior and superior conjunctival fornices so as to retain the implant within the tear fluid and/or against the tissues of the eye.Type: ApplicationFiled: June 8, 2018Publication date: April 11, 2019Inventors: Yair Alster, Eugene de Juan, JR., Cary J. Reich, Stephen Boyd, David Sierra, Jose D. Alejandro, K. Angela Macfarlane, Douglas Sutton
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Patent number: 10245348Abstract: Described is a process for making a dry and stable hemostatic composition, said process comprising a) providing a first component comprising a dry preparation of a coagulation inducing agent, b) providing a second component comprising a dry preparation of a biocompatible polymer suitable for use in hemostasis, c) providing said first component and said second component in a combined form in a final container, c1) either by filling said first component and said second component into said final container so as to obtain a dry mixture in said final container, c2) or by providing said first component or said second component in said final container and adding said second component or said first component so as to obtain a combination of said first component with said second component in said final container, d) finishing the final container to a storable pharmaceutical device containing said first component and said second component in a combined form as a dry and stable hemostatic composition.Type: GrantFiled: July 20, 2015Date of Patent: April 2, 2019Assignees: Baxter International Inc., Baxter Healthcare SAInventors: Andreas Goessl, Atsushi Edward Osawa, Cary J. Reich
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Patent number: 10191303Abstract: Bimodulus multifocal ophthalmic lenses for correcting presbyopia include an inner optic portion characterized by a rigidity greater than a rigidity of an outer peripheral portion. When applied to an eye, the ophthalmic lenses are configured to provide one or more lenticular volumes between the posterior surface of the lens and the cornea. The ophthalmic lenses are further characterized by features on a surface of the lens for improving multifocal visual acuity. The disclosure further relates to methods of correcting presbyopia using the ophthalmic lenses.Type: GrantFiled: July 28, 2016Date of Patent: January 29, 2019Assignee: NexisVision, Inc.Inventors: Eugene de Juan, Jr., Cary J. Reich, Matt Clarke, Kuangmon Ashley Tuan, Raymond Lum, Jose D. Alejandro
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Patent number: 10166142Abstract: A therapeutic device that can release a therapeutic agent comprising a porous structure coupled to a container comprising a reservoir. The reservoir can comprise a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in a patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. The length of the channels extending from the first side to the second side may comprise an effective length greater than a distance across the porous structure from the first side to the second side. The therapeutic device may comprise a penetrable barrier to inject therapeutic agent into the device when implanted in the patient.Type: GrantFiled: August 3, 2012Date of Patent: January 1, 2019Assignee: ForSight Vision4, Inc.Inventors: Eugene De Juan, Jr., Yair Alster, Kathleen Cogan Farinas, K. Angela MacFarlane, Cary J. Reich, Randolph E. Campbell, Signe Erickson
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Publication number: 20180321511Abstract: Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include an inner optic portion having a scaffold between an anterior portion and a posterior portion. The scaffold is characterized by a substantially uniform thickness formed from a material characterized by a modulus that his higher than the modulus of the peripheral portion. Openings within the scaffold are filled with a low modulus material. When applied to an eye, the lenses are configured to provide one or more lenticular volumes between the posterior surface of the lens and the cornea. The disclosure further relates to methods of correcting refractive errors of an eye such as astigmatism or spherical aberration using the ophthalmic lenses.Type: ApplicationFiled: November 9, 2017Publication date: November 8, 2018Inventors: Eugene de Juan, JR., Cary J. Reich, Matt Clarke, Kuangmon Ashley Tuan, Raymond Lum, Jose D. Alejandro
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Publication number: 20180292403Abstract: A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.Type: ApplicationFiled: November 8, 2017Publication date: October 11, 2018Inventors: Eugene de Juan, JR., Yair Alster, Steven M. Chamow, Kathleen C. Farinas, Hanson S. Gifford, III, K. Angela Macfarlane, Cary J. Reich, Michael Barrett, Randolph E. Campbell, Robert George, Douglas Sutton
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Patent number: 10039671Abstract: A method for providing faster visual and functional recovery of patients following refractive surgery such as laser assisted in situ keratomileusis (LASIK) is disclosed. The method comprises providing a covering to the eye of a patient comprising an inner portion having an inner rigidity and at least one inner radius of curvature; and an outer portion having an outer rigidity and at least one outer radius of curvature; wherein the inner rigidity is greater than the outer rigidity.Type: GrantFiled: October 23, 2013Date of Patent: August 7, 2018Assignee: NexisVision, Inc.Inventors: Eugene de Juan, Jr., Cary J. Reich, Yair Alster, Matt Clarke, Kuangmon Ashley Tuan, Brian Levy
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Patent number: 10036900Abstract: Ophthalmic lenses for correcting refractive error of an eye are disclosed. Ophthalmic lenses include an inner optic portion configured to be disposed over the optical region of the cornea and having a central portion disposed between an anterior portion and a posterior portion. The inner optic portions configured to at least partially diverge from the shape of the cornea to provide at least one lenticular volume between a posterior surface of the inner optic portion and the cornea. The central portion may be characterized by a thickness from 50 ?m to 900 ?m and a modulus form 20 MPa to 1500 MPa.Type: GrantFiled: August 31, 2016Date of Patent: July 31, 2018Assignee: NexisVision, Inc.Inventors: Eugene de Juan, Jr., Cary J. Reich, Yair Alster, Matt Clarke, Kuangmon Ashley Tuan, Brian Levy, Raymond Lum, Jose D. Alejandro
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Publication number: 20180193133Abstract: A therapeutic lens for the treatment of an epithelial defect comprises a layer of therapeutic material disposed over the stroma and/or Bowman's membrane to inhibit water flow from the tear liquid to the stroma and/or Bowman's membrane, such that corneal deturgescence can be restored to decrease corneal swelling and light scattering. The layer may cover and protect nerve fibers to decrease pain. The layer may comprise an index of refraction to inhibit light scatter from an anterior surface of the stroma and/or Bowman's membrane. The lens may comprise a curved anterior surface that provides functional vision for the patient when the epithelium regenerates. The layer of therapeutic material can be positioned on the eye in many ways, for example with a spray that is cured to adhere the layer to the exposed surface of the stroma and/or Bowman's membrane.Type: ApplicationFiled: March 9, 2018Publication date: July 12, 2018Inventors: EUGENE DE JUAN, JR., CARY J. REICH, STEPHEN BOYD, YAIR ALSTER, DAVID SIERRA, HANSON S. GIFFORD, JOSE D. ALEJANDRO, RICHARD L. LINDSTROM, K. ANGELA MACFARLANE, DOUGLAS SUTTON, JOHN ANTHONY SCHOLL