Patents by Inventor Cary Reich
Cary Reich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160022695Abstract: The present invention is directed to compositions of bimatoprost, processes of preparing these compositions, devices comprising these compositions, and methods of lowering intraocular pressure.Type: ApplicationFiled: March 27, 2014Publication date: January 28, 2016Inventors: Cary Reich, Carlos Schuler, Qiang Ye, Logan Stark, Rachna Jain
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Publication number: 20160008171Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: September 18, 2015Publication date: January 14, 2016Inventors: Eugene de Juan, JR., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Patent number: 9168222Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: April 29, 2014Date of Patent: October 27, 2015Assignee: Mati Therapeutics Inc.Inventors: Eugene De Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S Gifford, Mark Deem
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Patent number: 9107748Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.Type: GrantFiled: January 22, 2014Date of Patent: August 18, 2015Assignee: ForSight Labs, LLCInventors: Eugene de Juan, Jr., Stephen Boyd, Hanson Gifford, Cary Reich
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Publication number: 20150224200Abstract: An implant for insertion into a punctum of a patient comprises a body. The body has a distal end, a proximal end, and an axis therebetween. The distal end of the body is insertable distally through the punctum into the canalicular lumen. The body comprises a therapeutic agent included within an agent matrix drug core. Exposure of the agent matrix to the tear fluid effects an effective therapeutic agent release into the tear fluid over a sustained period. The body has a sheath disposed over the agent matrix to inhibit release of the agent away from the proximal end. The body also has an outer surface configured to engage luminal wall tissues so as to inhibit expulsion when disposed therein. In specific embodiments, the agent matrix comprises a non-bioabsorbable polymer, for example silicone in a non-homogenous mixture with the agent.Type: ApplicationFiled: January 16, 2015Publication date: August 13, 2015Applicant: Mati Therapeutics Inc.Inventors: Eugene de Juan, JR., Stephen Boyd, Hanson S. Gifford, III, Mark Deem, Cary Reich
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Patent number: 9084662Abstract: Disclosed are devices and methods for treatment of eye disease. The suprachoroidal space is used as a conduit within which to place a drug delivery device. One such drug delivery device may be a tube, wicking element, bioabsorbable polymer structure, or other configuration of drug delivery substrate. The delivery device may include a port on the proximal end to assist in repeat injection, and may include a reservoir to either collect flow from the aqueous to concentrate it along the length of the device, or act as a repository for injected agent.Type: GrantFiled: January 17, 2007Date of Patent: July 21, 2015Assignee: Transcend Medical, Inc.Inventors: Hanson S. Gifford, III, Angela MacFarlane, Cary Reich
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Patent number: 9050765Abstract: An intraocular lens comprises an optical element adapted to be implanted within the capsular bag of a human eye. The optical element includes one or more internal layers formed by one or more planes that are moveable relative to one another in order to effect the power of the optical element.Type: GrantFiled: March 14, 2012Date of Patent: June 9, 2015Assignee: ForSight Labs, LLCInventors: Stephen Boyd, Cary Reich
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Publication number: 20140328894Abstract: An implant for insertion into a punctum of a patient comprises a body. The body has a distal end, a proximal end, and an axis therebetween. The distal end of the body is insertable distally through the punctum into the canalicular lumen. The body comprises a therapeutic agent included within an agent matrix drug core. Exposure of the agent matrix to the tear fluid effects an effective therapeutic agent release into the tear fluid over a sustained period. The body has a sheath disposed over the agent matrix to inhibit release of the agent away from the proximal end. The body also has an outer surface configured to engage luminal wall tissues so as to inhibit expulsion when disposed therein. In specific embodiments, the agent matrix comprises a non-bioabsorbable polymer, for example silicone in a non-homogenous mixture with the agent.Type: ApplicationFiled: July 16, 2014Publication date: November 6, 2014Inventors: Eugene de Juan, JR., Cary Reich, Stephen Boyd, Hanson S. Gifford, Mark Deem
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Publication number: 20140242064Abstract: A system for delivering a therapeutic agent to a nasopharyngeal mucosa target comprises a foam generating mechanism, a gas, a therapeutic agent in liquid form that inhibits mucus production, and a delivery device. Actuation of the foam generating mechanism entraps gaseous bubbles from the gas in the liquid thereby forming a foam. The therapeutic agent is dispersed in the foam which has an expanded configuration adapted to fill a nasopharyngeal space and deliver the therapeutic agent to the mucosa targets. The delivery device is for delivering the foam to the nasopharyngeal space. The foam may also have a collapsed configuration for removal from the nasopharyngeal space or for concentration of the therapeutic agent onto the mucosa.Type: ApplicationFiled: January 9, 2014Publication date: August 28, 2014Applicant: The Foundry, LLCInventors: John Morriss, Cary Reich, Hanson Gifford
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Publication number: 20140236293Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: April 29, 2014Publication date: August 21, 2014Applicant: Mati Therapeutics Inc.Inventors: Eugene De Juan, JR., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Patent number: 8795711Abstract: An implant for insertion into a punctum of a patient comprises a body. The body has a distal end, a proximal end, and an axis therebetween. The distal end of the body is insertable distally through the punctum into the canalicular lumen. The body comprises a therapeutic agent included within an agent matrix drug core. Exposure of the agent matrix to the tear fluid effects an effective therapeutic agent release into the tear fluid over a sustained period. The body has a sheath disposed over the agent matrix to inhibit release of the agent away from the proximal end. The body also has an outer surface configured to engage luminal wall tissues so as to inhibit expulsion when disposed therein. In specific embodiments, the agent matrix comprises a non-bioabsorbable polymer, for example silicone in a non-homogenous mixture with the agent.Type: GrantFiled: April 2, 2007Date of Patent: August 5, 2014Assignee: Mati Therapeutics Inc.Inventors: Eugene de Juan, Jr., Cary Reich, Stephen Boyd, Hanson G. Gifford, III, Mark Deem
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Patent number: 8747884Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: July 18, 2011Date of Patent: June 10, 2014Assignee: Mati Therapeutics Inc.Inventors: Eugene De Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Publication number: 20140135918Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.Type: ApplicationFiled: January 22, 2014Publication date: May 15, 2014Applicant: FORSIGHT LABS, LLCInventors: Eugene de Juan, JR., Stephen Boyd, Hanson Gifford, Cary Reich
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Patent number: 8715346Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.Type: GrantFiled: April 8, 2013Date of Patent: May 6, 2014Assignee: ForSight Labs, LLCInventors: Eugene de Juan, Jr., Stephen Boyd, Hanson Gifford, Cary Reich
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Publication number: 20140058507Abstract: Described herein are intraocular lenses and methods of implantation. In one aspect, the lens includes a shape changing optical element; a force translation element having a first end region coupled to the optical element and a second end region extending towards a ciliary structure, and an attachment portion coupled to the second end region of the force translation element and configured to contact the ciliary structure. The force translation element is configured to functionally transmit movements of the ciliary structure into a force exerted upon the optical element to effect an accommodating and a disaccommodating change of the optical element.Type: ApplicationFiled: October 30, 2013Publication date: February 27, 2014Applicant: FORSIGHT LABS, LLCInventors: Cary Reich, Eugene de Juan, JR., Yair Alster
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Publication number: 20140033800Abstract: Disclosed herein are improved therapeutic devices and methods and improved porous structures and measurement apparatus for use with therapeutic devices. In many embodiments, a porous structure is measured based on diffusion of the gas through the porous structure. The gas measurement may comprise an amount of gas measured to determine a resistance of the porous structure to diffusion. The diffusion of the gas through the porous structure can be used to determine release of a therapeutic agent through the porous structure, such that targeted amounts of therapeutic agent can be released for extended times and such that therapeutic device reservoir volume and porous frit structure can be tuned to release the therapeutic agent for an extended time above a target amount for the extended time.Type: ApplicationFiled: November 10, 2011Publication date: February 6, 2014Applicant: ForSight Vision4, Inc.Inventors: Kathleen Cogan Farinas, Cary Reich, Randolph E. Campbell, Signe Erikson, Michael S. Barrett
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Publication number: 20130226295Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.Type: ApplicationFiled: April 8, 2013Publication date: August 29, 2013Applicant: ForSight Labs, LLCInventors: Eugene de Juan, JR., Stephen Boyd, Hanson Gifford, Cary Reich
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Patent number: 8414646Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.Type: GrantFiled: December 22, 2008Date of Patent: April 9, 2013Assignee: Forsight Labs, LLCInventors: Eugene De Juan, Jr., Stephen Boyd, Hanson Gifford, Cary Reich
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Publication number: 20120253459Abstract: Described herein are intraocular lenses and methods of implantation. In one aspect, the lens includes a shape changing optical element; a force translation element having a first end region coupled to the optical element and a second end region extending towards a ciliary structure, and an attachment portion coupled to the second end region of the force translation element and configured to contact the ciliary structure. The force translation element is configured to functionally transmit movements of the ciliary structure into a force exerted upon the optical element to effect an accommodating and a disaccommodating change of the optical element.Type: ApplicationFiled: February 3, 2012Publication date: October 4, 2012Inventors: Cary Reich, Eugene de Juan, JR., Yair Alster
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Publication number: 20120168422Abstract: An intraocular lens comprises an optical element adapted to be implanted within the capsular bag of a human eye. The optical element includes one or more internal layers formed by one or more planes that are moveable relative to one another in order to effect the power of the optical element.Type: ApplicationFiled: March 14, 2012Publication date: July 5, 2012Inventors: Stephen Boyd, Cary Reich