Patents by Inventor Caryn Lang Bowe

Caryn Lang Bowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glycopegylated erythropoietin
    Patent number: 8916360
    Abstract: The present invention provides conjugates between erythropoietin and PEG moieties. The conjugates are linked via an intact glycosyl linking group interposed between and covalently attached to the peptide and the modifying group. The conjugates are formed from glycosylated peptides by the action of a glycosyltransferase. The glycosyltransferase ligates a modified sugar moiety onto a glycosyl residue on the peptide. Also provided are methods for preparing the conjugates, methods for treating various disease conditions with the conjugates, and pharmaceutical formulations including the conjugates.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: December 23, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Caryn Lang Bowe
  • GLYCOPEGYLATED ERYTHROPOIETIN
    Publication number: 20120107867
    Abstract: The present invention provides conjugates between erythropoietin and PEG moieties. The conjugates are linked via an intact glycosyl linking group interposed between and covalently attached to the peptide and the modifying group. The conjugates are formed from glycosylated peptides by the action of a glycosyltransferase. The glycosyltransferase ligates a modified sugar moiety onto a glycosyl residue on the peptide. Also provided are methods for preparing the conjugates, methods for treating various disease conditions with the conjugates, and pharmaceutical formulations including the conjugates.
    Type: Application
    Filed: June 10, 2011
    Publication date: May 3, 2012
    Applicant: NOVO NORDISK A/S
    Inventors: Shawn DeFrees, David A. Zopf, Caryn Lang Bowe