Abstract: The present disclosure relates to repair devices configured for use in fixing or approximating tissues, such as cardiac valve tissues and particularly the leaflets of a regurgitant mitral valve. The repair device includes a shaft, a pair of proximal elements pivotally coupled to the shaft and extending from the shaft, and a pair of distal elements pivotally coupled to the shaft and extending from the shaft. The proximal and distal elements are configured so that targeted tissue can be grasped therebetween. The distal elements and/or the proximal elements include adjustable arms that can be extended and retracted to adjust the length of the gripping elements to provide more effective grasping of targeted tissues.

Abstract: A skin care system including a dispensing device configured to administer a light therapy and a plasma treatment, and an applicator configured to apply a formula, comprising a reservoir configured to hold the formula, a roller ball configured to apply the formula, an attachment configured to attach the cartridge to the dispensing device, and a microcontroller configured to direct the dispensing devices to apply the plasma treatment.

Abstract: A skin care system including a dispensing device configured to administer a light therapy and a vibration treatment, and an applicator configured to apply a formula, including a reservoir configured to hold the formula, a roller ball configured to apply the formula, a connection configured to attach the cartridge to the dispensing device, and a microcontroller configured to direct the dispensing device to apply the vibration treatment.

Abstract: An applicator comprising a reservoir configured to hold a formula, a roller ball configured to apply the formula, a contact-less piston, configured to dispense the formula, and a piston magnet disposed underneath the contact-less piston, wherein the piston magnet is configured to move the piston in response to a magnetic field.

Abstract: A system for applying a formula, the system including an applicator including a reservoir configured to hold a formula, a roller ball configured to apply the formula, and an accelerometer configured to map a surface as the roller ball rolls and applies the formula, an attachment configured to couple the applicator to a dispensing device and a dispensing device including a light source configured to apply light treatment, where the dispensing device is configured to accept the applicator.

Abstract: A system for dispensing a skin formula, the system including a base device configured to dispense a formula into an applicator, an applicator configured to apply the formula, the applicator including a reservoir configured to hold the formula, a roller ball configured to apply the formula, and an attachment configured to attach the applicator to the base device and a dispensing device.

Abstract: A skin care system including a dispensing device configured to administer a light therapy and a microcurrent treatment, and an applicator configured to apply a formula, comprising a reservoir configured to hold the formula, a first roller ball configured to apply the formula, a connection configured to attach the cartridge to the dispensing device, and a microcontroller configured to direct the dispensing device to apply the microcurrent treatment.

Abstract: Fixation device for fixation of leaflets of a heart valve includes a central assembly and at least one arm moveably coupled to the central assembly. The at least one arm includes a body portion having a first end and a second end and a longitudinal axis defined therebetween, the second end being moveable between a closed position and an open position, the body portion having opposing body lateral sides, each body lateral side extending between the first end and the second end, the body portion having a body portion width defined between the opposing body lateral sides. The at least one arm further includes first and second nondeformable wing extensions, each wing extension extending laterally from a respective lateral side, each wing extension having a lateral outer edge, wherein a maximum arm width is defined between the outer lateral edge of the first wing extension and the outer lateral edge of the second wing extension.

Abstract: Fixation device for fixation of leaflets of a heart valve includes a central assembly and at least one arm moveably coupled to the central assembly. The at least one arm includes a body portion having a first end and a second end and a longitudinal axis defined therebetween, the second end being moveable between a closed position and an open position, the body portion having opposing body lateral sides, each body lateral side extending between the first end and the second end, the body portion having a body portion width defined between the opposing body lateral sides. The at least one arm further includes first and second nondeformable wing extensions, each wing extension extending laterally from a respective lateral side, each wing extension having a lateral outer edge, wherein a maximum arm width is defined between the outer lateral edge of the first wing extension and the outer lateral edge of the second wing extension.

Abstract: Fixation device for fixation of leaflets of a heart valve includes a central assembly and at least one arm moveably coupled relative to the central assembly. The at least one arm includes a deformable frame having a first end and a second end and a longitudinal axis defined therebetween, the second end being moveable between a closed position and an open position. The deformable frame further includes first and second deformable flex portions, each flex portion extending along a respective lateral side of the deformable frame and having a deformed condition and an undeformed condition, and each flex portion having an outer lateral edge. The at least one arm has a maximum deformed arm lateral cross-dimension with the flex portions in the deformed condition.

Abstract: An electronic sensor for pH measurement may be used (e.g. an ISFET sensor, a glass electrode sensor, an antimony electrode sensor) to collect skin pH information from a subject. An application is provided on a computing device that detects and analyzes the pH measurements reported by the electronic sensor to determine skin pH values for analysis. Based on the determined skin pH values and questionnaire responses, the application may recommend a skin regimen/treatment to restore skin function. The application may also provide visualizations of predicted effects of the skin regimen on a skin condition of the subject.

Abstract: Fixation device for fixation of leaflets of a heart valve includes a central assembly and at least one arm moveably coupled to the central assembly. The at least one arm includes a body portion having a first end and a second end and a longitudinal axis defined therebetween, the second end being moveable between a closed position and an open position, the body portion having opposing body lateral sides, each body lateral side extending between the first end and the second end, the body portion having a body portion width defined between the opposing body lateral sides. The at least one arm further includes first and second nondeformable wing extensions, each wing extension extending laterally from a respective lateral side, each wing extension having a lateral outer edge, wherein a maximum arm width is defined between the outer lateral edge of the first wing extension and the outer lateral edge of the second wing extension.

Abstract: The present disclosure relates to repair devices configured for use in fixing or approximating tissues, such as cardiac valve tissues and particularly the leaflets of a regurgitant mitral valve. The repair device includes a shaft, a pair of proximal elements pivotally coupled to the shaft and extending from the shaft, and a pair of distal elements pivotally coupled to the shaft and extending from the shaft. The proximal and distal elements are configured so that targeted tissue can be grasped therebetween. The distal elements and/or the proximal elements include adjustable arms that can be extended and retracted to adjust the length of the gripping elements to provide more effective grasping of targeted tissues.

Abstract: The present disclosure relates to repair devices configured for use in fixing or approximating tissues, such as cardiac valve tissues and particularly the leaflets of a regurgitant mitral valve. The repair device includes a shaft, a pair of proximal elements pivotally coupled to the shaft and extending from the shaft, and a pair of distal elements pivotally coupled to the shaft and extending from the shaft. The proximal and distal elements are configured so that targeted tissue can be grasped therebetween. The distal elements and/or the proximal elements include adjustable arms that can be extended and retracted to adjust the length of the gripping elements to provide more effective grasping of targeted tissues.

Abstract: The present disclosure relates to repair devices configured for use in fixing or approximating tissues, such as cardiac valve tissues and particularly the leaflets of a regurgitant mitral valve. The repair device includes a shaft, a pair of proximal elements pivotally coupled to the shaft and extending from the shaft, and a pair of distal elements pivotally coupled to the shaft and extending from the shaft. The proximal and distal elements are configured so that targeted tissue can be grasped therebetween. The distal elements and/or the proximal elements include adjustable arms that can be extended and retracted to adjust the length of the gripping elements to provide more effective grasping of targeted tissues.