Abstract: The present disclosure generally relates to antibodies, antigen binding fragments thereof, polypeptides, and immunoconjugates that bind to CD123 antigen (the ? chain of the interleukin-3 receptor) and deliver a payload to CD123 expressing cells. The payload is a topoisomerase inhibitor that efficiently kills CD123 expressing tumor cells while sparing hematopoietic stem cells and mature hematopoietic cells.

Abstract: A grounding clip for a plug-in universal (PIU) module enclosure in an optical network element includes a first wing portion shaped to be positioned between and in contact with a first side of a faceplate of the network element and the chassis, a second wing portion shaped to be positioned between and in contact with a second side of the faceplate and the chassis, and a center portion shaped to extend over and to be in contact with the PIU module enclosure when the grounding assembly is installed in the network element. The grounding clip includes an opening through which a fastener electrically and mechanically couples the grounding clip to a printed circuit board (PCB) and to the chassis when installed, the PCB being installed within the chassis and configured to be communicably coupled to a PIU module when the PIU module is installed in the PIU module enclosure.