Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.

Abstract: A method for setting an axial position and gap dimension of a gap between one or more score blades and an anvil shaft of a rotary scoring device, includes providing a control system including a controller, at least one sensor, and at least one adjusting device actuated by the control system, and actuating the at least one adjusting device in response to the at least one sensor sensing a deviation from a desired state, thereby setting the axial position or the gap dimension between the one or more score blades and the anvil shaft. The method further includes actuating the at least one adjusting device is achieved as a result of the control system operating in a closed feedback loop, and sensing by the at least one sensor occurring with or without disruption of operation of the rotary scoring device.

Abstract: A passive safety catheter assembly configured to inhibit access to the distal tip of a needle cannula prior to release of a catheter insertion assembly from a catheter hub. The passive safety catheter assembly includes a safety clip assembly configured to transition between a first position in which the safety clip assembly selectively couples the catheter insertion assembly to the catheter hub, and a second position in which the safety clip assembly traps the sharp distal tip of the needle cannula within the safety clip assembly prior to release of the coupling between the catheter insertion assembly and the catheter hub.

Abstract: In a first aspect, a polymer film includes a polyimide, wherein the polyimide includes two or more dianhydrides, including a first monomer that is a crankshaft monomer and a second monomer that is a rigid non-rotational monomer, and one or more diamines including a third monomer that is a flexible monomer. The crankshaft monomer and the flexible monomer include a combined 65 to 99 mol % of the total of all three monomers. The rigid non-rotational monomer includes 1 to 35 mol % of the total of all three monomers. The polymer film has a dielectric dissipation loss factor, Df, of 0.005 or less, a water absorption of 2.0% or less and a water vapor transport rate of 50 (g×mil)/(m2×day) or less.

Abstract: In a first aspect, a polymer film includes a polyimide, wherein the polyimide includes two or more dianhydrides, including 15 to 35 mol % of a first monomer that is a crankshaft monomer and 15 to 35 mol % of a second monomer that is a flexible monomer, and two or more diamines, including 1 to 35 mol % of a third monomer that is a rotational inhibitor monomer and 15 to 49 mol % a fourth monomer that is a rigid rotational monomer, wherein the mol % of each monomer is based on the total of all four monomers. The polymer film has a dielectric dissipation loss factor, Df, of 0.005 or less, a water absorption of 2.0% or less and a water vapor transport rate of 50 (g×mil)/(m2×day) or less.

Abstract: In one aspect, a single layer polymer film includes 25 to 97.5 wt % of a polyimide having a refractive index of 1.74 or less, 0.5 to 20 wt % of a matting agent and 1 to 30 wt % of a black colorant. On an air side, the single layer polymer film has an L* color of 33 or less and a 60° gloss of 10 or less. In another aspect, a single layer polymer film includes 80 to 99 wt % of a polyimide having a refractive index of 1.74 or less and 1 to 30 wt % of a black colorant. A surface of the single layer polymer film has been textured and has a maximum roughness (Spv) of 7 ?m or more, an L* of 33 or less and a 60° gloss of 10 or less.

Abstract: In a first aspect, a polymer film includes a polyimide. The polyimide includes one or more dianhydrides and one or more diamines. Each of the dianhydrides and diamines is selected from the group consisting of crankshaft monomers, flexible monomers, rigid rotational monomers, rigid non-rotational monomers, and rotational inhibitor monomers. The polymer film has a Df of 0.005 or less, a water absorption of 2.0% or less and a water vapor transport rate of 50 (g×mil)/(m2×day) or less. In a second aspect, a metal-clad laminate includes the polymer film of first aspect and a first metal layer adhered to a first outer surface of the polymer film. In a third aspect, an electronic device includes the polymer film of the first aspect.

Abstract: A dual lumen IV administration set includes a first lumen having an inner diameter of a first value. A second lumen is paired with the first lumen, and the second lumen has an inner diameter of a second value that is greater than the first value. A flow merger merges flow output from a distal end of the first lumen and flow output from a distal end of the second lumen to form a single flow output in an exit lumen. An injection port intersects the first lumen, thereby providing injection access to flow therethrough, prior to merging with the flow output of the second lumen.

Abstract: Systems and methods of additively manufacturing leak resistant objects are disclosed. Provided herein are methods of forming objects having walls and/or surfaces that are resistant to leaks. Objects disclosed are formed from or manufactured from compositions, including metals, polymers, and combinations thereof. Objects provided herein are made from methods of forming individual shells, forming of series shells, and layer-by-layer forming of objects. Further disclosed are methods of interconnecting shells, layers, and processes for transitioning therebetween the shells and layers.

Abstract: In a first aspect, a polyimide film includes a polyimide derived from a dianhydride and a diamine. The dianhydride, the diamine or both the dianhydride and the diamine include an alicyclic monomer, an aliphatic monomer or both an alicyclic monomer and an aliphatic monomer. The polyimide film has an L* of at least 90, a b* of 1.25 or less, a yellowness index of 2.25 or less and a haze of less than 1% for a film thickness of 50 ?m. In a second aspect, an electronic device includes the polyimide film of the first aspect.

Abstract: In a first aspect, a polyimide corn position has a glass transition temperature of less than 300° C. and includes a polyimide derived from a dianhydride, a fluorinated aromatic diamine and an aliphatic diamine. A polyimide film made from the polyimide composition has a b* of less than one for a film thickness of at least 30 microns.

Abstract: In a first aspect, an article includes an inorganic substrate and a polymer film layer. The inorganic substrate includes a material including a ceramic, a glass, a glass-ceramic or a mixture thereof. The material includes a metal cation selected from the group consisting of silicon, aluminum, titanium, zirconium, tantalum, niobium and mixtures thereof and oxygen. The polymer film layer includes a polymer including an imide group. From an interface where the inorganic substrate contacts the polymer film layer, a line-profile of a CNO— signal from negative secondary ion mass spectroscopy decreases as it moves away from the interface and into the bulk of the polymer film layer.

Abstract: In a first aspect, a polyimide film includes a dianhydride and a diamine. The dianhydride, the diamine or both the dianhydride and the diamine include an alicyclic monomer, an aliphatic monomer or both an alicyclic monomer and an aliphatic monomer. The polyimide film has a b* of 1.25 or less and a yellowness index of 2.25 or less for a film thickness of 50 ?m. The polyimide film is formed by: (a) polymerizing the dianhydride and the diamine in the presence of a first solvent to obtain a polyamic acid solution; (b) imidizing the polyamic acid solution to form a substantially imidized solution; (c) casting the substantially imidized solution to form a film; and (d) drying the film.

Abstract: A dual lumen IV administration set includes a first lumen having an inner diameter of a first value. A second lumen is paired with the first lumen, and the second lumen has an inner diameter of a second value that is greater than the first value. A flow merger merges flow output from a distal end of the first lumen and flow output from a distal end of the second lumen to form a single flow output in an exit lumen. An injection port intersects the first lumen, thereby providing injection access to flow therethrough, prior to merging with the flow output of the second lumen.

Abstract: In a first aspect, a single layer polymer film includes 60 to 99 wt % of a crosslinked polyimide, having a gel fraction in the range of from 20 to 100% and a refractive index of 1.74 or less, and 1 to 40 wt % of a colorant. A surface of the single layer polymer film has been textured and has a maximum roughness (Spv) of 6 ?m or more, an L* color of 30 or less and a 60° gloss of 15 or less. In a second aspect, a coverlay for a printed circuit board includes the single layer polymer film of the first aspect. In third and fourth aspects, processes are disclosed for forming a single layer polymer film including a crosslinked polyimide film including a dianhydride and a diamine.

Abstract: The present invention relates generally to the field of gates. More specifically, the present invention relates to a drive through gate device primarily comprised of at least one support post, at least one gate assembly, and at least one spring. The gate assembly is preferably attached on each end to a support post, wherein each support post is supported by a ground frame member. The gate assembly can then be driven over and through by a user in a vehicle such that the gate assembly rests on the ground surface in front of the device. After a vehicle has finished driving over and through the gate assembly, the gate assembly is returned to the vertical position parallel with the support posts via the spring.

Abstract: In a first aspect, a coating solution includes a soluble polymer and a crosslinking precursor. The soluble polymer includes an imide group. The crosslinking precursor includes a first amine group that is either reactive or passivated towards crosslinking and one or more additional amine groups, wherein the one or more additional amine groups has been passivated towards crosslinking such that the crosslinking precursor can be chemically converted, thermally converted, photo-converted or dissociated to form at least two reactive amines. In a second aspect, a process for forming a polymer film includes: (a) casting a coating solution, (b) activating the crosslinking precursor using an external stimulus to form at least two reactive amines and crosslink the polymer, and (c) drying the polymer film. The coating solution includes a soluble polymer, including an imide group, and a crosslinking precursor.

Abstract: In a first aspect, a polyimide corn position has a glass transition temperature of less than 300° C. and includes a polyimide derived from a dianhydride, a fluorinated aromatic diamine and an aliphatic diamine. A polyimide film made from the polyimide composition has a b* of less than one for a film thickness of at least 30 microns.

Abstract: In a first aspect, a polyimide film includes a dianhydride, a fluorinated aromatic diamine and an aliphatic diamine. The polyimide film has a b* of less than one for a film thickness of at least 30 microns and a glass transition temperature of less than 300° C. In a second aspect, an electronic device includes the polyimide film of the first aspect.

Abstract: A safety catheter insertion device configured to automatically retract a needle cannula following insertion of a catheter assembly and to inhibit release of the catheter assembly from the safety catheter insertion device until the needle cannula has been retracted for the purpose of inhibiting inadvertent needle sticks. The safety catheter insertion device including an advancement arm slidably coupled to a needle housing assembly and configured to shift between a first position in which a needle cannula traverses through a catheter hub coupling portion of the advancement arm to inhibit release of a catheter assembly, and a second position in which one or more tabs of the advancement arm interact with one or more retention arms of the needle housing assembly to enable a biasing mechanism to shift the needle assembly to a proximal position and enable release of the catheter assembly from the safety catheter insertion device.