Abstract: Medical devices are disclosed for compression of tissue and/or implants via a guide wire during provisional reduction in fracture fixation surgeries and other types of surgeries. Accordingly, an example device includes a housing with first and second apertures and a longitudinal axis. The device also includes a plate inside that itself includes a third aperture. The third aperture establishes a plane that is oblique with respect to the longitudinal axis while the plate is under spring bias from a spring in the housing. The spring helps maintain the oblique angle with respect to the longitudinal axis to lock the medical device at a desired position along the wire while the wire concurrently extends through the first, second, and third apertures. Methods for manufacturing, providing, and using the medical device(s) are also disclosed.

Abstract: A system configured to monitor and characterize motions of a user is disclosed herein. The system can include a wearable article including a tubular body comprising a resilient material, a flexible circuit including a fluid-phase conductor configured to generate a first signal, and an inertial measurement unit (“IMU”) coupled to the resilient material, wherein the IMU is configured to generate a second signal. The system can further include a processor communicably coupled to the flexible circuit and the IMU.

Abstract: A portable sampling device includes a sampling housing at least partially enclosing an inner chamber; at least one pumping element disposed within the inner chamber and configured to facilitate airflow through the device; and at least one gas sensor disposed within the inner chamber and configured to detect and/or characterize one or more gases in the airflow.

Abstract: A portable sampling device includes a housing at least partially enclosing an inner chamber and an airflow assembly disposed within the inner chamber and comprising a portion of an airflow path. The airflow assembly includes a portion of a printed circuit board (PCB); a manifold configured to be sealably coupled to the portion of the PCB to define at least one airflow channel disposed between an inner surface of the manifold and an outer surface of the PCB; and one or more pumping elements positioned on the PCB.

Abstract: A system for further filtering a liquid extract material after an initial extraction process. In an embodiment, the system includes a semi-rigid filter cup that is substantially cylindrical, the filter cup having a top and a bottom, wherein the top is oriented to receive filter media prior to a filtration process, and material to be filtered during the filtration process. The filter cup includes an integrated deformable flange at the top of the filter cup, an integrated top o-ring that is integrated into the top of the integrated deformable flange and an integrated bottom o-ring that is integrated into the bottom of the integrated deformable flange.

Abstract: A portable sampling device includes a sampling housing at least partially enclosing an inner chamber; at least one pumping element disposed within the inner chamber and configured to facilitate airflow through the device; and at least one gas sensor disposed within the inner chamber and configured to detect and/or characterize one or more gases in the airflow.

Abstract: A system for further filtering a liquid extract material after an initial extraction process. In an embodiment, the system includes a semi-rigid filter cup that is substantially cylindrical, the filter cup having a top and a bottom, wherein the top is oriented to receive filter media prior to a filtration process, and material to be filtered during the filtration process. The filter cup includes an integrated deformable flange at the top of the filter cup, an integrated top o-ring that is integrated into the top of the integrated deformable flange and an integrated bottom o-ring that is integrated into the bottom of the integrated deformable flange.

Abstract: A filtration vessel, having within constituent filter media is formed using plastic injection molding to meet the interior specifications of a high-pressure filtration encasement system while remaining a separate replaceable component. The encasement system supports and encases walls of the filtration vessel enabling the vessel to be designed with sufficient strength and resiliency to form a seal and constrain filter media prior to and after use without necessitating construction to endure independent high-pressure operations. The bottom or base of the vessel includes a plurality of holes through which the filtrate may flow. Interposed between the base of the vessel and the filter media is a semi-permeable barrier imbedded into the injection molded walls and base of the vessel. The barrier prevents residue from contaminating the filtrate.

Abstract: A portable sampling device includes a housing at least partially enclosing an inner chamber and an airflow assembly disposed within the inner chamber and comprising a portion of an airflow path. The airflow assembly includes a portion of a printed circuit board (PCB); a manifold configured to be sealably coupled to the portion of the PCB to define at least one airflow channel disposed between an inner surface of the manifold and an outer surface of the PCB; and one or more pumping elements positioned on the PCB.

Abstract: A sampling device is constructed having an airflow path from a size-selective inlet to a device outlet, without using any tubing. The size-selective inlet includes at least one of an impactor, a filter, a cyclone, and an inhalable inlet. The device includes a sampling assembly configured to be removably coupled directly to a sampling device housing (e.g., without using tubing), and an airflow assembly that may be constructed without using tubing.

Abstract: A sampling device is constructed having an airflow path from a size-selective inlet to a device outlet, without using any tubing. The size-selective inlet includes at least one of an impactor, a filter, a cyclone, and an inhalable inlet. The device includes a sampling assembly configured to be removably coupled directly to a sampling device housing (e.g., without using tubing), and an airflow assembly that may be constructed without using tubing.

Abstract: In one embodiment, a magnetic gas sensor includes a first ferromagnetic layer, a second ferromagnetic layer, and a gas-sensitive metallic interlayer positioned between the first and second ferromagnetic layers, wherein at least one physical property of the metallic interlayer changes in the presence of a gas that is to be detected, wherein a magnetic coupling between the first and second ferromagnetic layers, and a magnetic state of the sensor, can change depending upon the state of the physical property of the metallic interlayer.

Abstract: A system controls net thrust of a steam turbine having a stepped rotating shaft. A first leak off line fluidly couples a first stage of a turbine section to a packing near a stepped portion on the rotating shaft. A second leak off line fluidly couples a second stage of the turbine section that has a pressure different from the first stage to a step area immediately adjacent to the stepped portion, and a connection line fluidly couples the first leak off line to the second leak off line. The lines include control valves such that a controller can actively control the net thrust by regulating thrust pressure on the stepped portion using steam from the first and second stages of the turbine section. The controller may also prevent damage to an active retractable seal using the control valves.

Abstract: A system controls net thrust of a steam turbine having a stepped rotating shaft. A first leak off line fluidly couples a first stage of a turbine section to a packing upstream of a stepped portion on the rotating shaft. A second leak off line fluidly couples a second stage of the turbine section that is subsequent to the first stage to a step area upstream of the stepped portion, and a connection line fluidly couples the first leak off line to the second leak off line. The lines include control valves such that a controller can actively control the net thrust by regulating thrust pressure on the stepped portion using steam from the first and second stages of the turbine section. The controller may also prevent damage to an active retractable seal using the control valves.

Abstract: A doll's seamless garment which is adapted to be dressed, fitted and be removed in a life-like manner from a doll having a height in the range of above 8 cm to about 32 cm, wherein the doll is bendable at least in part. The garment is molded from an elastomeric material or rubber having an average modulus of elasticity of less than 1 MN/m2. The garment wall thickness is preferably in the range of about 1 mm to about 3 mm. Further disclosed is a skin. The skin is adapted to be dressed, fitted and removed from a doll to transform the doll into a different character or object, and wherein the skin is molded in at least one part from an elastomeric material. The skin may have a wall thickness from 1 to 3 mm, the material having an average modulus of elasticity of less than 1 MN/m2. The garments are easily manipulated by children and provide opportunities for creative play. Still further disclosed is a play set comprising, in cooperative combination, a doll donned and fitted with a garment.

Abstract: A system controls net thrust of a steam turbine having a stepped rotating shaft. A first leak off line fluidly couples a first stage of a turbine section to a packing upstream of a stepped portion on the rotating shaft. A second leak off line fluidly couples a second stage of the turbine section that is subsequent to the first stage to a step area upstream of the stepped portion, and a connection line fluidly couples the first leak off line to the second leak off line. The lines include control valves such that a controller can actively control the net thrust by regulating thrust pressure on the stepped portion using steam from the first and second stages of the turbine section. The controller may also prevent damage to an active retractable seal using the control valves.

Abstract: A system controls net thrust of a steam turbine having a stepped rotating shaft. A first leak off line fluidly couples a first stage of a turbine section to a packing near a stepped portion on the rotating shaft. A second leak off line fluidly couples a second stage of the turbine section that has a pressure different from the first stage to a step area immediately adjacent to the stepped portion, and a connection line fluidly couples the first leak off line to the second leak off line. The lines include control valves such that a controller can actively control the net thrust by regulating thrust pressure on the stepped portion using steam from the first and second stages of the turbine section. The controller may also prevent damage to an active retractable seal using the control valves.

Abstract: Agents and methods for qualitative and quantitative analysis a protein complex or protein complexes using isotope-labeled symmetrical bifunctional crosslinkers and mass spectrometry are provided. Targeting moieties, cell permeability moieties, or affinity moieties, may be appended to the bifunctional crosslinkers. The isotope-labeled symmetrical bifunctional crosslinkers may be used in a kit or as a library.

Abstract: A multi-sided playing die capable of indicating at least one of a plurality of symbols on sides of the die comprises an energy storage device within the die and a trigger for discharging energy from the energy storage device to cause rotation of the die out of a position in which said at least one symbol is indicated. The die may include a casing formed from parts arranged to rotate relative to each other to cause rotation of the die.

Abstract: Provided herein are agents that bind to soluble beta-amyloid. Also provided are in vivo and in vitro methods for detecting soluble beta-amyloid in a sample that may include brain tissue.