Patents by Inventor Casi Giulio

Casi Giulio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazolidine linker for the conjugation of drugs to antibodies
    Patent number: 9198979
    Abstract: In one aspect, there is provided a protein-drug conjugate compound comprising a protein covalently attached by a linker to one or more drug moieties, wherein the linker has a half-life of from 1 hour to 50 hours in phosphate buffered saline at 37° C. A carbonyl derivative of LU103793 is also described that can be used in a protein-drug conjugate compound comprising an antibody covalently attached by a linker to the drug moiety comprising, consisting or consisting essentially of the carbonyl derivative.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: December 1, 2015
    Assignee: Philogen S.P.A.
    Inventor: Casi Giulio
  • Thiazolidine Linker for the Conjugation of Drugs to Antibodies
    Publication number: 20130309257
    Abstract: In one aspect, there is provided a protein-drug conjugate compound comprising a protein covalently attached by a linker to one or more drug moieties, wherein the linker has a half-life of from 1 hour to 50 hours in phosphate buffered saline at 37° C. A carbonyl derivative of LU103793 is also described that can be used in a protein-drug conjugate compound comprising an antibody covalently attached by a linker to the drug moiety comprising, consisting or consisting essentially of the carbonyl derivative.
    Type: Application
    Filed: March 25, 2013
    Publication date: November 21, 2013
    Applicant: Philogen S.P.A.
    Inventor: Casi Giulio