Abstract: Described herein are pharmaceutical rectal foam formulations, useful, for example, for the rectal administration of therapeutic agents, such as 5-aminosalicylic acid (5-ASA), as well as methods of making such foam formulations, and therapeutic methods using them.

Abstract: The invention relates to a microstructured optical fiber for generating supercontinuum light upon feeding of pump light. The light can be incoherent light. The microstructured optical fiber has a first section and a second section, where the first and second sections have one or more different features. The invention also relates to a supercontinuum source comprising a microstructured optical fiber according to the invention.

Abstract: The invention relates to a microstructured optical fiber for generating supercontinuum light upon feeding of pump light. The light can be incoherent light. The microstructured optical fiber has a first section and a second section, where the first and second sections have one or more different features. The invention also relates to a supercontinuum source comprising a microstructured optical fiber according to the invention.

Abstract: The invention relates to a microstructured optical fiber for generating incoherent supercontinuum light upon feeding of pump light. The microstructured optical fiber has a first section and a second section. A cross-section through the second section perpendicularly to a longitudinal axis of the fiber has a second relative size of microstructure elements and preferably a second pitch that is smaller than a blue edge pitch for the second relative size of microstructure elements. The invention also relates to an incoherent supercontinuum source comprising a microstructured optical fiber according to the invention.

Abstract: Liquid formulations containing picosulfate and magnesium citrate are provided. The formulations are useful to treat constipation or for the clearance of the bowel prior to X-ray examination, endoscopy or surgery.

Abstract: The invention relates to a microstructured optical fiber for generating incoherent supercontinuum light upon feeding of pump light. The microstructured optical fiber has a first section and a second section. A cross-section through the second section perpendicularly to a longitudinal axis of the fiber has a second relative size of microstructure elements and preferably a second pitch that is smaller than a blue edge pitch for the second relative size of microstructure elements. The invention also relates to an incoherent supercontinuum source comprising a microstructured optical fiber according to the invention.

Abstract: Disclosed are improved granular pharmaceutical preparations, together with improved methods and apparatus for preparation of granules for use in such preparations. Such methods are especially useful for making granules for solid oral dose pharmaceutical preparations, and are particularly suited to the production of granules comprising 5-aminosalicylic acid (5-ASA) for the treatment of inflammatory bowel disease. The granules exhibit a more sharply peaked length distribution, and hence aspect ratio distribution, and have a consequently much sharper dissolution profile after further processing.

Abstract: Disclosed are improved granular pharmaceutical preparations, together with improved methods and apparatus for preparation of granules for use in such preparations. Such methods are especially useful for making granules for solid oral dose pharmaceutical preparations, and are particularly suited to the production of granules comprising 5-aminosalicylic acid (5-ASA) for the treatment of inflammatory bowel disease. The granules exhibit a more sharply peaked length distribution, and hence aspect ratio distribution, and have a consequently much sharper dissolution profile after further processing.

Abstract: Disclosed are improved granular pharmaceutical preparations, together with improved methods and apparatus for preparation of granules for use in such preparations. Such methods are especially useful for making granules for solid oral dose pharmaceutical preparations, and are particularly suited to the production of granules comprising 5-aminosalicylic acid (5-ASA) for the treatment of inflammatory bowel disease. The granules exhibit a more sharply peaked length distribution, and hence aspect ratio distribution, and have a consequently much sharper dissolution profile after further processing.

Abstract: Disclosed are improved granular pharmaceutical preparations, together with improved methods and apparatus for preparation of granules for use in such preparations. Such methods are especially useful for making granules for solid oral dose pharmaceutical preparations, and are particularly suited to the production of granules comprising 5-aminosalicylic acid (5-ASA) for the treatment of inflammatory bowel disease. The granules exhibit a more sharply peaked length distribution, and hence aspect ratio distribution, and have a consequently much sharper dissolution profile after further processing.