Patents by Inventor Casper W. Barnes

Casper W. Barnes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7006857
    Abstract: A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.
    Type: Grant
    Filed: April 28, 2003
    Date of Patent: February 28, 2006
    Assignee: OptiScan Biomedical Corporation
    Inventors: James R. Braig, Charles E. Kramer, Bernhard B. Sterling, Daniel S. Goldberger, Peng Zheng, Arthur M. Shulenberger, Rick Trebino, Richard A. King, Casper W. Barnes
  • Patent number: 6944486
    Abstract: A method and apparatus of determining the analyte concentration of a test sample is described. A temperature gradient is introduced into the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. The modulation of the temperature gradient is controlled by a surface temperature modulation. A transfer function is determined that relates the surface temperature modulation to the modulation of the measured infrared radiation. Reference and analytical signals are detected. In the presence of the selected analyte, phase and magnitude differences in the transfer function are detected. These phase and magnitude differences, having a relationship to analyte concentration, are measured, correlated and processed to determine analyte concentration in the sample.
    Type: Grant
    Filed: June 6, 2003
    Date of Patent: September 13, 2005
    Assignee: Optiscan Biomedical Corporation
    Inventors: James R. Braig, Charles E. Kramer, Bernhard B. Sterling, Daniel S. Goldberger, Peng Zheng, Arthur M. Shulenberger, Rick Trembino, Richard A. King, Casper W. Barnes
  • Publication number: 20040087841
    Abstract: A method and apparatus of determining the analyte concentration of a test sample is described. A temperature gradient is introduced into the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. The modulation of the temperature gradient is controlled by a surface temperature modulation. A transfer function is determined that relates the surface temperature modulation to the modulation of the measured infrared radiation. Reference and analytical signals are detected. In the presence of the selected analyte, phase and magnitude differences in the transfer function are detected. These phase and magnitude differences, having a relationship to analyte concentration, are measured, correlated and processed to determine analyte concentration in the sample.
    Type: Application
    Filed: June 6, 2003
    Publication date: May 6, 2004
    Inventors: James R. Braig, Charles E. Kramer, Bernhard B. Sterling, Daniel S. Goldberger, Peng Zheng, Arthur M. Shulenberger, Rick Trebino, Richard A. King, Casper W. Barnes
  • Patent number: 6731961
    Abstract: A device and method for determining analyte concentrations within a material sample are provided. A modulating temperature gradient is induced in the sample and resultant, emitted infrared radiation is measured at selected analyte absorbance peaks and reference wavelengths. The modulating temperature gradient is controlled by a surface temperature modulation. One embodiment provides a transfer function relating the surface temperature modulation to a modulation of the measured infrared radiation. Phase and magnitude differences in the transfer function are detected in the presence of the sought-after analyte. These phase and magnitude differences, having a relationship to analyte concentration, are measured, correlated and processed to determine analyte concentration in the material sample. Another embodiment provides a method for transforming thermal phase spectra to absorption spectra for consistent determination of analyte concentration within the sample.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: May 4, 2004
    Assignee: OptiScan Biomedical Corp.
    Inventors: James R. Braig, W. Dale Hall, Casper W. Barnes, Peng Zheng, Jennifer H. Gable
  • Publication number: 20040059206
    Abstract: A device and method for determining analyte concentrations within a material sample are provided. A modulating temperature gradient is induced in the sample and resultant, emitted infrared radiation is measured at selected analyte absorbance peaks and reference wavelengths. The modulating temperature gradient is controlled by a surface temperature modulation. One embodiment provides a transfer function relating the surface temperature modulation to a modulation of the measured infrared radiation. Phase and magnitude differences in the transfer function are detected in the presence of the sought-after analyte. These phase and magnitude differences, having a relationship to analyte concentration, are measured, correlated and processed to determine analyte concentration in the material sample. Another embodiment provides a method for transforming thermal phase spectra to absorption spectra for consistent determination of analyte concentration within the sample.
    Type: Application
    Filed: September 26, 2003
    Publication date: March 25, 2004
    Inventors: James R. Braig, W. Dale Hall, Casper W. Barnes, Peng Zheng, Jennifer H. Gable
  • Publication number: 20030199742
    Abstract: A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.
    Type: Application
    Filed: April 28, 2003
    Publication date: October 23, 2003
    Inventors: James R. Braig, Charles E. Kramer, Bernhard B. Sterling, Daniel S. Goldberger, Peng Zheng, Arthur M. Shulenberger, Rick Trebino, Richard A. King, Casper W. Barnes
  • Publication number: 20030133118
    Abstract: A device and method for determining analyte concentrations within a material sample are provided. A modulating temperature gradient is induced in the sample and resultant, emitted infrared radiation is measured at selected analyte absorbance peaks and reference wavelengths. The modulating temperature gradient is controlled by a surface temperature modulation. One embodiment provides a transfer function relating the surface temperature modulation to a modulation of the measured infrared radiation. Phase and magnitude differences in the transfer function are detected in the presence of the sought-after analyte. These phase and magnitude differences, having a relationship to analyte concentration, are measured, correlated and processed to determine analyte concentration in the material sample. Another embodiment provides a method for transforming thermal phase spectra to absorption spectra for consistent determination of analyte concentration within the sample.
    Type: Application
    Filed: November 8, 2002
    Publication date: July 17, 2003
    Inventors: James R. Braig, W. Dale Hall, Casper W. Barnes, Peng Zheng, Jennifer H. Gable
  • Patent number: 6580934
    Abstract: A method and apparatus of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. The modulation of the temperature gradient is controlled by a surface temperature modulation. A transfer function is determined that relates the surface temperature modulation to the modulation of the measured infrared radiation. Reference and analytical signals are detected. In the presence of the selected analyte, phase and magnitude differences in the transfer function are detected. These phase and magnitude differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: June 17, 2003
    Assignee: Optiscan Biomedical Corporation
    Inventors: James R. Braig, Charles E. Kramer, Bernhard B. Sterling, Daniel S. Goldberger, Peng Zheng, Arthur M. Shulenberger, Rick Trembino, Richard A. King, Casper W. Barnes
  • Patent number: 6577885
    Abstract: A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: June 10, 2003
    Assignee: OptiScan Biomedical Corporation
    Inventors: James R. Braig, Charles E. Kramer, Bernhard B. Sterling, Daniel S. Goldberger, Peng Zheng, Arthur M. Shulenberger, Rick Trebino, Richard A. King, Casper W. Barnes
  • Patent number: 6556850
    Abstract: A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: April 29, 2003
    Assignee: Optiscan Biomedical Corporation
    Inventors: James R. Braig, Charles E. Kramer, Bernhard B. Sterling, Daniel S. Goldberger, Peng Zheng, Arthur M. Shulenberger, Rick Trebino, Richard A. King, Casper W. Barnes
  • Patent number: 6161028
    Abstract: A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.
    Type: Grant
    Filed: March 10, 1999
    Date of Patent: December 12, 2000
    Assignee: Optiscan Biomedical Corporation
    Inventors: James R. Braig, Charles E. Kramer, Bernhard B. Sterling, Daniel S. Goldberger, Peng Zheng, Arthur M. Shulenberger, Rick Trebino, Richard A. King, Casper W. Barnes
  • Patent number: 5910995
    Abstract: A decoder capable of decoding audio signals encoded using analog noise reduction techniques, particularly Dolby SR, is implemented by means of digital signal processing. The typical decoding paradigm used by analog Dolby SR decoders is modified to overcome the problems caused by delay which is introduced by the digital implementation. A gain factor is factored out of the feedback transfer function and is placed in the forward signal path of each stage of the digital decoder. A single control circuit can then be used to generate coefficients which define transfer functions of each filter stage of the signal path. Linear interpolation techniques are used to limit the number of coefficient entries necessary to emulate the transfer function of an analog Dolby SR decoder. The digital decoder structure can be inverted to produce a digital encoder which is capable of implementing any noise reduction standard desired, including Dolby SR.
    Type: Grant
    Filed: November 22, 1995
    Date of Patent: June 8, 1999
    Assignees: Sony Corporation of Japan, Sony Pictures Entertainment Inc.
    Inventors: Laura Mercs, Paul M. Embree, Casper W. Barnes
  • Patent number: 5609576
    Abstract: Impedance to fluid flow in a fluid delivery line is measured. Two techniques are used depending on the flow rate selected. For high flow rates, the pump is controlled to vary the flow rate and the change in pressure is divided by the change in flow to directly determine the resistance. For low flow rates, a processor controls the pump to pump flow quantities in accordance with a pseudo-random binary code. The resulting pressure signal sensed at the conduit is decoded in accordance with that code. Pressures received during code periods of no flow are subtracted from pressures received during code periods of flow. Pressure offset is also removed and a least squares estimation approach is used with a linear prediction model to determine impedance. The coefficients determined in the model are used to calculate the resistance to fluid flow of the system. A quality supervisor monitors the resistance determination process and controls the display of resistance depending on the quality determined.
    Type: Grant
    Filed: September 13, 1994
    Date of Patent: March 11, 1997
    Assignee: IVAC Medical Systems, Inc.
    Inventors: Gregory I. Voss, Robert D. Butterfield, Gail D. Baura, Casper W. Barnes
  • Patent number: 5048528
    Abstract: A Doppler velocity spectrum produced by radial projection in a two-dimensional Fourier frequency domain is processed to suppress alias spectral terms. The projected spectrum is divided into windows using an iterative algorithm which centers the spectral mean. The window containing data samples which maximizes a weighted score based upon the width and maximal value of samples within the window is used to determine which window contains true spectral components. Spectral components in other windows are then suppressed.
    Type: Grant
    Filed: November 15, 1990
    Date of Patent: September 17, 1991
    Assignee: North American Philips Corp.
    Inventors: Laura Superina, Casper W. Barnes
  • Patent number: 4809249
    Abstract: Apparatus for mapping moving objects by determining the cross-correlation function between two digitally sampled ultrasound A-line signals comprises a plurality of fractional step delay (FSD) digital interpolation filters which estimate the value of one of said input signals at intervals between said samples and a plurality of one-bit correlation circuits each of which determines the correlation between the first signal and the output of one of said interpolation filters.
    Type: Grant
    Filed: April 21, 1986
    Date of Patent: February 28, 1989
    Assignee: North American Philips Corporation
    Inventor: Casper W. Barnes
  • Patent number: 4761752
    Abstract: A circuit for determining the cross-correlation function between two digitally sampled signals comprises a plurality of fractional step delay (FSD) digital interpolation filters which estimate the value of one of said input signals at intervals between said samples and a plurality of correlation circuits each of which determines the correlation between the first signal and the output of one of said interpolation filters.
    Type: Grant
    Filed: April 21, 1986
    Date of Patent: August 2, 1988
    Assignee: North American Philips Corporation
    Inventor: Casper W. Barnes
  • Patent number: 4676250
    Abstract: An ultrasound attenuation scanner measures the local attenuation of tissues from pulse echo A-line data. An adaptive filter with a transfer function which is the inverse of the tissue undergoing examination operates on the complex envelope of the RF signal.
    Type: Grant
    Filed: November 7, 1985
    Date of Patent: June 30, 1987
    Assignee: North American Philips Corporation
    Inventor: Casper W. Barnes
  • Patent number: 4542744
    Abstract: Apparatus and methods for remote identification of tissue types model the scattering of ultrasound energy from living tissue as an autoregressive or autoregressive moving average random process. Autoregressive or autoregressive moving average models of candidate tissue types are generated from pulse-echo data that is known to come from that particular tissue type. Kalman prediction error filters are used for each candidate tissue type to generate estimates of the probability that an unknown pulse echo signal belongs to the class generated by that tissue type. Unknown pulse-echo signals are filtered in a specific Kalman filter to test the hypothesis that the unknown signal belongs to the class associated with that particular Kalman filter.
    Type: Grant
    Filed: March 23, 1983
    Date of Patent: September 24, 1985
    Assignee: North American Philips Corporation
    Inventors: Casper W. Barnes, Farhad Towfiq
  • Patent number: 4512196
    Abstract: An ultrasound transducer having an annular acoustic aperture is utilized in combination with an echo-ultrasound imaging system having an FM detector. The off-axis transfer function characteristics of the annular transducer substantially improve the lateral resolution of the imaging system as compared with prior art systems which utilized round or rectangular transducer apertures.
    Type: Grant
    Filed: September 30, 1983
    Date of Patent: April 23, 1985
    Assignee: North American Philips Corporation
    Inventor: Casper W. Barnes
  • Patent number: 4100927
    Abstract: Flow regulating apparatus comprises a turbulent-flow valve with a fluid supply connected at the upstream side thereof. A fixed pressure bias is applied to the fluid upstream of the valve whereby the mass flow rate of fluid through the valve is directly proportional to the pressure differential across the apparatus when these variations are within a selected pressure range. Such flow regulation may be used in a system for introducing a metered amount of liquid fuel into an air stream to provide a combustible air-fuel mixture having a substantially constant air-to-fuel ratio. With this system air is passed through a constricted zone to increase its velocity to sonic, and the area of the constricted zone is varied in correlation with operating demands imposed upon the engine for which the mixture is produced.
    Type: Grant
    Filed: June 18, 1976
    Date of Patent: July 18, 1978
    Assignee: Dresser Industries, Inc.
    Inventor: Casper W. Barnes, Jr.