Patents by Inventor Cassandra A. Gauthier

Cassandra A. Gauthier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cycloalkyl Lactam Derivatives As Inhibitors Of 11-Beta-Hydroxysteroid Dehydrogenase 1
    Publication number: 20080214621
    Abstract: The present invention provides compounds of formula I that are useful as potent and selective inhibitors of 11-beta hydroxysteroid dehydrogenase 1. The present invention further provides a pharmaceutical composition which comprises a compound of Formula I, or a pharmaceutical salt thereof, and a pharmaceutically acceptable carrier, diluent, or excipient. In addition, the present invention compositions containing these compounds for the treatment of metabolic syndrome, diabetes, hyperglycemia obesity, hypertension, hyperlipidemia, other symptoms associated with hyperglycemia, and related disorders. Formula I wherein G1 is methylene or ethylene; L is —(C1-C4)alkylene-, —S—, —CH(OH)—, or —O—; R0 is Formula II or Formula III and the other substituents are as defined in the claims.
    Type: Application
    Filed: December 16, 2005
    Publication date: September 4, 2008
    Inventors: Thomas Daniel Aicher, Mark Joseph Chicarelli, Cassandra A. Gauthier, Ronald Jay Hinklin, Hongqi Tian, Owen Brendan Wallace, Alexei Pavlovych Krasutsky, John Gordon Allen