Abstract: A rotational atherectomy device that includes an expandable head that can clean a blockage from vessel larger than its rest diameter, in which the drive shaft may rotate in two opposite directions and may have different abrasive characteristics for each rotation direction. In one direction, the head may be configured for cutting and/or slicing, which may be well suited to removing particularly soft blockage material. In the other direction, the head may be configured for grinding, scraping and/or sanding, which may be well suited to removing particularly hard blockage material. The head includes one or more arms that are pivotally or hingedly attached to the drive shaft. One or more abrasive elements are disposed on or are attached to the one or more arms. The abrasive elements have a cutting feature, such as a sharpened edge that cuts like a razor blade when the drive shaft is rotated in the “cutting” direction.

Abstract: The invention provides a rotational atherectomy system, device and method comprising a flexible, elongated, rotatable drive shaft with a pre-curved abrasive section disposed within a catheter that deforms the abrasive section to a substantially straight profile and, when the abrasive section is moved distally out of the catheter, the abrasive section resumes its pre-curved profile. Directional ablation is achieved by rotation of the drive shaft along its pre-curved axis as the abrasive section is urged against a portion of the lumen wall.

Abstract: The invention provides a rotational atherectomy system, device and method comprising a bi-directional drive shaft with a flexible ablation element disposed at the distal end of the drive shaft. The flexible ablation element comprises a first retracted position for insertion into vasculature and a second expanded position for ablation, i.e., cutting, sanding and/or grinding. The ablation element comprises more than one flexible finger or blade which allows changing, in certain embodiments, of curvature radius to fit inside a deployment catheter and/or enlarge to the diameter of larger lumens, up to at least 9 mm in diameter. Bi-directional rotation of the expanded ablation element allows cutting in one rotational direction and grinding and/or sanding in the opposite rotational direction.

Abstract: The invention provides a rotational atherectomy system, device and method having a flexible, elongated, rotatable catheter tube that is split into two elements, a biasing element and a cutting element, distally and wherein the biasing element and cutting element are capable of forming a first and retracted position for insertion into a lumen and a second and expanded position for ablation. The biasing element is biased in the expanded position, thereby placing a biasing force against the lumen wall and pressing the cutting element against the opposite side of the lumen wall for directional cutting and/or grinding, either by rotation, axial translation, vibration or a combination thereof.

Abstract: The invention provides a rotational atherectomy system, device and method comprising a bi-directional drive shaft with a flexible ablation element disposed at the distal end of the drive shaft. The flexible ablation element comprises a first retracted position for insertion into vasculature and a second expanded position for ablation, i.e., cutting, sanding and/or grinding. The ablation element comprises more than one flexible finger or blade which allows changing, in certain embodiments, of curvature radius to fit inside a deployment catheter and/or enlarge to the diameter of larger lumens, up to at least 9 mm in diameter. Bi-directional rotation of the expanded ablation element allows cutting in one rotational direction and grinding and/or sanding in the opposite rotational direction.

Abstract: The invention provides a rotational atherectomy system, device and method comprising a flexible, elongated, rotatable drive shaft with a pre-curved abrasive section disposed within a catheter that deforms the abrasive section to a substantially straight profile and, when the abrasive section is moved distally out of the catheter, the abrasive section resumes its pre-curved profile. Directional ablation is achieved by rotation of the drive shaft along its pre-curved axis as the abrasive section is urged against a portion of the lumen wall.

Abstract: A rotational atherectomy device that includes an expandable head that can clean a blockage from vessel larger than its rest diameter, in which the drive shaft may rotate in two opposite directions and may have different abrasive characteristics for each rotation direction. In one direction, the head may be configured for cutting and/or slicing, which may be well suited to removing particularly soft blockage material. In the other direction, the head may be configured for grinding, scraping and/or sanding, which may be well suited to removing particularly hard blockage material. The head includes one or more arms that are pivotally or hingedly attached to the drive shaft. One or more abrasive elements are disposed on or are attached to the one or more arms. The abrasive elements have a cutting feature, such as a sharpened edge that cuts like a razor blade when the drive shaft is rotated in the “cutting” direction.

Abstract: The invention provides a rotational atherectomy system, device and method comprising a flexible, elongated, rotatable catheter tube that is split into two elements, a biasing element and a cutting element, distally and wherein the biasing element and cutting element are capable of forming a first and retracted position for insertion into a lumen and a second and expanded position for ablation. The biasing element is biased in the expanded position, thereby placing a biasing force against the lumen wall and pressing the cutting element against the opposite side of the lumen wall for directional cutting and/or grinding, either by rotation, axial translation, vibration or a combination thereof.