Patents by Inventor Cassandra L. LOWENSTEIN

Cassandra L. LOWENSTEIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-CEACAM antibodies and uses thereof
    Patent number: 11760801
    Abstract: The disclosure provided herein relates to monospecific and multispecific antibodies, that bind CEACAM1 and optionally CEACAM5 and/or CEACAM6, and methods of producing and using the described antibodies.
    Type: Grant
    Filed: September 14, 2020
    Date of Patent: September 19, 2023
    Assignee: Janssen Biotech, Inc.
    Inventors: Wendell Lamar B Blackwell, Douglas V. Dolfi, Cassandra L. Lowenstein, Raluca I. Verona
  • TRISPECIFIC ANTIBODY TARGETING CD79b, CD20, AND CD3
    Publication number: 20220315663
    Abstract: Provided herein are multispecific antibodies, including trispecific antibodies that bind to CD79b, CD20 and CD3, and bispecific antibodies that bind to CD79b and CD3, and multispecific antigen-binding fragments thereof. Also described are related polynucleotides capable of encoding the provided multispecific antibodies or multispecific antigen-binding fragments, cells expressing the provided multispecific antibodies or multispecific antigen-binding fragments, as well as associated vectors and detectably labeled multispecific antibodies or multispecific antigen-binding fragments. In addition, methods of producing and using the provided multispecific antibodies and multispecific antigen-binding fragments are described. Further provided herein are isolated antibodies that bind to CD79b and antigen-binding fragments thereof.
    Type: Application
    Filed: March 23, 2022
    Publication date: October 6, 2022
    Inventors: Rajkumar GANESAN, Anna KUCHNIO, Cassandra L. LOWENSTEIN, Ulrike PHILIPPAR, Sanjaya SINGH, Nele VLOEMANS, Danlin YANG
  • ANTI-CEACAM ANTIBODIES AND USES THEREOF
    Publication number: 20210095024
    Abstract: The disclosure provided herein relates to monospecific and multispecific antibodies, that bind CEACAM1 and optionally CEACAM5 and/or CEACAM6, and methods of producing and using the described antibodies.
    Type: Application
    Filed: September 14, 2020
    Publication date: April 1, 2021
    Inventors: Wendell Lamar B BLACKWELL, Douglas V. DOLFI, Cassandra L. LOWENSTEIN, Raluca I. VERONA