Patents by Inventor Catherine A. Evans

Catherine A. Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic compounds and uses thereof
    Patent number: 12152032
    Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: November 26, 2024
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Catherine A. Evans, Somarajannair Janardanannair, Andre Lescarbeau, Tao Liu, Martin R. Tremblay
  • JAK2 INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20240368122
    Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of JAK2 enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with JAK2 signaling with the compounds and compositions of the disclosure.
    Type: Application
    Filed: August 19, 2022
    Publication date: November 7, 2024
    Inventors: Lucian V. DiPietro, Ravi Kurukulasuriya, Amael Madec, Catherine A. Evans, Cary Griffin Fridrich, Rebecca Jane Swett, Alessandro Boezio, Alexander M. Taylor, Thomas H. McLean, Christopher Thomson
  • Indole AHR inhibitors and uses thereof
    Patent number: 12077542
    Abstract: The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: September 3, 2024
    Assignee: Ikena Oncology, Inc.
    Inventors: Alfredo C. Castro, Catherine A. Evans
  • Crystal forms of an ALK2 inhibitor
    Patent number: 12071438
    Abstract: The invention relates to crystalline forms of an ALK2 inhibitor, methods of their preparation, and related pharmaceutical preparations thereof. The invention also relates to pharmaceutical uses of the crystalline forms.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: August 27, 2024
    Assignee: Keros Therapeutics, Inc.
    Inventors: Sarah Bethune, Krista Diaz, Catherine A. Evans
  • CDK INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20240190855
    Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of CDK enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with CDK signaling with the compounds and compositions of the disclosure.
    Type: Application
    Filed: February 11, 2022
    Publication date: June 13, 2024
    Inventors: Alexander M. Taylor, Timothy F. Briggs, Nicolas A. Pabon, Jing He, Andre Lescarbeau, Alessandro Boezio, Catherine A. Evans, Cary Griffin Fridrich, Brian P. Kelley, Elaine B. Krueger, Ravi Kurukulasuriya, Thomas H. McLean
  • HETEROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20240050437
    Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Application
    Filed: November 30, 2022
    Publication date: February 15, 2024
    Inventors: Jeffery L. Kutok, David G. Winkler, Vito J. Palombella, Alfredo C. Castro, Catherine A. Evans, Somarajannair Janardanannair, Andre Lescarbeau, Tao Liu, Martin R. Tremblay
  • INDOLE AHR INHIBITORS AND USES THEREOF
    Publication number: 20230028336
    Abstract: The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.
    Type: Application
    Filed: May 6, 2022
    Publication date: January 26, 2023
    Inventors: Alfredo C. CASTRO, Catherine A. EVANS
  • Heterocyclic compounds and uses thereof
    Patent number: 11541059
    Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: January 3, 2023
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Jeffery L. Kutok, David G. Winkler, Vito J. Palombella, Alfredo C. Castro, Catherine A. Evans, Somarajannair Janardanannair, Andre Lescarbeau, Tao Liu, Martin R. Tremblay
  • HETEROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20220372038
    Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Application
    Filed: March 15, 2021
    Publication date: November 24, 2022
    Inventors: Alfredo C. Castro, Catherine A. Evans, Somarajannair Janardanannair, Andre Lescarbeau, Tao Liu, Martin R. Tremblay
  • Indole AHR inhibitors and uses thereof
    Patent number: 11358969
    Abstract: The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: June 14, 2022
    Assignee: IKENA ONCOLOGY, INC.
    Inventors: Alfredo C. Castro, Catherine A. Evans
  • CRYSTAL FORMS OF AN ALK2 INHIBITOR
    Publication number: 20210238185
    Abstract: The invention relates to crystalline forms of an ALK2 inhibitor, methods of their preparation, and related pharmaceutical preparations thereof. The invention also relates to pharmaceutical uses of the crystalline forms.
    Type: Application
    Filed: April 23, 2021
    Publication date: August 5, 2021
    Inventors: Sarah BETHUNE, Krista DIAZ, Catherine A. EVANS
  • Heterocyclic compounds and uses thereof
    Patent number: 10941162
    Abstract: Trisubstituted bicyclic heterocyclic compounds (e.g., pyridopyrimidinones) and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: March 9, 2021
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Catherine A. Evans, Martin R. Tremblay
  • Heterocyclic compounds and uses thereof
    Patent number: 10919914
    Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: February 16, 2021
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Catherine A. Evans, Martin R. Tremblay
  • HETEROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20210000837
    Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Application
    Filed: March 11, 2020
    Publication date: January 7, 2021
    Inventors: Jeffery L. Kutok, David G. Winkler, Vito J. Palombella, Alfredo C. Castro, Catherine A. Evans, Somarajannair Janardanannair, Andre Lescarbeau, Tao Liu, Martin R. Tremblay
  • INDOLE AHR INHIBITORS AND USES THEREOF
    Publication number: 20200331917
    Abstract: The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.
    Type: Application
    Filed: April 8, 2020
    Publication date: October 22, 2020
    Inventors: Alfredo C. Castro, Catherine A. Evans
  • Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors
    Patent number: 10759806
    Abstract: Provided are isotopologues of isoquinolinone and quinazolinone compounds of formula (AB?) that modulate PI3 kinase activity, processes for the preparation of the compounds, pharmaceutical compositions comprising the compounds, and methods of treatment of diseases and disorders using the compounds or pharmaceutical compositions.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: September 1, 2020
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventor: Catherine A. Evans
  • HETEROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20190367521
    Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Application
    Filed: May 20, 2019
    Publication date: December 5, 2019
    Inventors: Alfredo C. Castro, Catherine A. Evans, Somarajannair Janardanannair, Andre Lescarbeau, Tao Liu, Martin R. Tremblay
  • HETEROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20190330240
    Abstract: Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
    Type: Application
    Filed: March 1, 2019
    Publication date: October 31, 2019
    Inventors: Alfredo C. Castro, Catherine A. Evans, Martin R. Tremblay
  • ISOTOPOLOGUES OF ISOQUINOLINONE AND QUINAZOLINONE COMPOUNDS AND USES THEREOF AS PI3K KINASE INHIBITORS
    Publication number: 20190202835
    Abstract: Provided are isotopologues of isoquinolinone and quinazolinone compounds of formula (AB?) that modulate PI3 kinase activity, processes for the preparation of the compounds, pharmaceutical compositions comprising the compounds, and methods of treatment of diseases and disorders using the compounds or pharmaceutical compositions.
    Type: Application
    Filed: March 16, 2017
    Publication date: July 4, 2019
    Inventor: Catherine A. Evans
  • Heterocyclic compounds and uses thereof
    Patent number: 10329299
    Abstract: Provided herein are compounds of Formula (I?) or (A?), pharmaceutical compositions comprising the compounds, and methods of use thereof. The compounds provided herein modulate kinase activity, including PI3 kinase activity, and are useful for treating diseases and conditions associated with kinase activity, including PI3 kinase activity.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: June 25, 2019
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Catherine A. Evans, Somarajannair Janardanannair, Andre Lescarbeau, Tao Liu, Martin R. Tremblay