Patents by Inventor Catherine E. Grubin

Catherine E. Grubin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cloning and expression of human islet glutamic acid decarboxylase autoantigen
    Patent number: 6025176
    Abstract: Human pancreatic islet cell glutamic acid decarboxylase (GAD), an autoantigen involved in the development of insulin-dependent diabetes mellitus (IDDM), has been cloned, sequenced and expressed by recombinant means. Recombinant human islet cell GAD polypeptides and antibodies specific to the GAD polypeptides can be used in methods of diagnosis and treatment, including use in immunoadsorptive therapy and the induction of immune tolerance.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: February 15, 2000
    Assignee: The Board of Regents of the University of Washington and ZymoGenetics, Inc.
    Inventors: Ake Lernmark, Allan E. Karlsen, Catherine E. Grubin, William Hagopian, Patrick J. O'Hara, Donald C. Foster
  • Cloning and expression of human islet glutamic acid decarboxylase autoantigen
    Patent number: 5792620
    Abstract: Human pancreatic islet cell glutamic acid decarboxylase (GAD), an autoantigen involved in the development of insulin-dependent diabetes mellitus (IDDM), has been cloned, sequenced and expressed by recombinant means. Recombinant human islet cell GAD polypeptides and antibodies specific to the GAD polypeptides can be used in methods of diagnosis and treatment, including use in immunoadsorptive therapy and the induction of immune tolerance.
    Type: Grant
    Filed: August 17, 1993
    Date of Patent: August 11, 1998
    Assignees: The Board of Regents of the University of Washington, ZymoGenetics, Inc.
    Inventors: Ake Lernmark, Allan E. Karlsen, Catherine E. Grubin, William Hagopian, Patrick J. O'Hara, Donald C. Foster