Patents by Inventor Catherine F. Foulon

Catherine F. Foulon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides from stannyl precursors
    Patent number: 5720935
    Abstract: A method of making a radiolabeled pyrimidine nucleoside or nucleotide is described. In the method, a stannylated pyrimidine nucleoside or nucleotide is contacted in an aqueous solution with a radioactive iodide, bromide, chlorine or astatine ion in the presence of an acidic hydrogen peroxide oxidizing solution comprising at least a 3:1 ratio of 30% hydrogen peroxide to 1N acid (v/v), whereby a water soluble pyrimidine nucleoside or nucleotide labeled with radioactive iodine, bromine, chlorine or astatine is formed. Kits suitable for practicing the method are also disclosed.
    Type: Grant
    Filed: June 9, 1995
    Date of Patent: February 24, 1998
    Assignee: President & Fellows of Harvard College
    Inventors: Amin I. Kassis, Catherine F. Foulon, S. James Adelstein
  • Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides
    Patent number: 5574148
    Abstract: A method of making a radiolabeled pyrimidine nucleoside or nucleotide is described. In the method an aqueous solution (i) a radioactive iodide, bromide, chlorine or astatide ion and (ii) a water soluble halomercuri pyrimidine nucleoside or nucleotide is contacted with an oxidizing agent, whereby a water soluble pyrimidine nucleoside or nucleotide labeled with radioactive iodine, bromine, chlorine or astatine is formed. Kits suitable for practicing the method are also disclosed.
    Type: Grant
    Filed: February 2, 1995
    Date of Patent: November 12, 1996
    Assignee: President U Fellows of Harvard College
    Inventors: Amin I. Kassis, Catherine F. Foulon, S. James Adelstein