Patents by Inventor Catherine Flores

Catherine Flores has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HEMATOPOIETIC STEM CELLS IN COMBINATORIAL THERAPY WITH IMMUNE CHECKPOINT INHIBITORS AGAINST CANCER
    Publication number: 20240226290
    Abstract: The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoictic stem cell mobilization yield synergistic effects in disease therapy.
    Type: Application
    Filed: January 12, 2024
    Publication date: July 11, 2024
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Duane Mitchell, Catherine Flores
  • Hematopoietic stem cells in combinatorial therapy with immune checkpoint inhibitors against cancer
    Patent number: 11904016
    Abstract: The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoietic stem cell mobilization yield synergistic effects in disease therapy.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: February 20, 2024
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Duane Mitchell, Catherine Flores
  • STEM CELL IMMUNOMODULATORY THERAPY FOR COVID-19 INFECTION
    Publication number: 20230183370
    Abstract: The disclosure provides methods of treating coronavirus infections (e.g., COVID-19) by administering hematopoietic stem cells, with or without an immune checkpoint inhibitor (e.g., PD-1 antagonist). The disclosure also provides methods of treating coronavirus infections (e.g., COVID-19) by adoptive cell transfer of polyclonal T cells and coronavirus-specific T cells (e.g., SARS-CoV-2-specific T cells).
    Type: Application
    Filed: April 2, 2021
    Publication date: June 15, 2023
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Duane Mitchell, Catherine Flores, Connor Francis
  • CCR2+ hematopoietic stem cells mediate T cell activation in adoptive cell therapy
    Patent number: 11464805
    Abstract: The combination of adoptive cell therapy with CCR2 positive (CCR2+) hematopoietic stem cell transplantation increases T cell activation and survival.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: October 11, 2022
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Duane Mitchell, Catherine Flores
  • CELLULAR MICRO-MASONRY SYSTEM
    Publication number: 20220119762
    Abstract: Described herein are systems and methods relating to cellular micro-masonry. Systems and methods as described herein allow a user to create three-dimensional (3D) structures of cells disposed in a 3D culture medium. Systems and methods as described herein provide for the manipulation and construction of cellular structures on a single, cell-by-cell, basis.
    Type: Application
    Filed: December 30, 2021
    Publication date: April 21, 2022
    Inventors: Sarah V. ELLISON, Thomas Ettor ANGELINI, Scott Arthur BANKS, Duane MITCHELL, Cameron MORLEY, Catherine FLORES
  • CCR2+ HEMATOPOIETIC STEM CELLS MEDIATE T CELL ACTIVATION IN ADOPTIVE CELL THERAPY
    Publication number: 20210283184
    Abstract: The combination of adoptive cell therapy with CCR2 positive (CCR2+) hematopoietic stem cell transplantation increases T cell activation and survival.
    Type: Application
    Filed: December 21, 2017
    Publication date: September 16, 2021
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Duane Mitchell, Catherine Flores
  • MATERIALS AND METHODS FOR THE TREATMENT OF LEWY BODY DISORDERS
    Publication number: 20210093670
    Abstract: The present disclosure provides methods for reducing Lewy Bodies in the central nervous system of a subject in need thereof by administering a T cell that is specific for an ?-synuclein mutant to the subject.
    Type: Application
    Filed: April 3, 2019
    Publication date: April 1, 2021
    Inventors: Vinata Vedam-Mai, Michael S. Okun, Catherine Flores, Duane Mitchell
  • HEMATOPOIETIC STEM CELLS IN COMBINATORIAL THERAPY WITH IMMUNE CHECKPOINT INHIBITORS AGAINST CANCER
    Publication number: 20210008200
    Abstract: The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoietic stem cell mobilization yield synergistic effects in disease therapy.
    Type: Application
    Filed: April 13, 2020
    Publication date: January 14, 2021
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Duane Mitchell, Catherine Flores
  • Hematopoietic stem cells in combinatorial therapy with immune checkpoint inhibitors against cancer
    Patent number: 10660954
    Abstract: The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoietic stem cell mobilization yield synergistic effects in disease therapy.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: May 26, 2020
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Duane Mitchell, Catherine Flores
  • HEMATOPOIETIC STEM CELLS IN COMBINATORIAL THERAPY WITH IMMUNE CHECKPOINT INHIBITORS AGAINST CANCER
    Publication number: 20180214544
    Abstract: The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoietic stem cell mobilization yield synergistic effects in disease therapy.
    Type: Application
    Filed: July 29, 2016
    Publication date: August 2, 2018
    Inventors: Duane Mitchell, Catherine Flores