Patents by Inventor Catherine Guenther

Catherine Guenther has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transgenic mice containing retinoid X receptor interacting protein gene disruptions
    Publication number: 20060137031
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in the LXRB gene. Such transgenic mice are useful as models for disease, such as diabetes. The present invention is also directed to identifying agents that modulate LXRB gene function, and as potential treatments for various disease states and disease conditions, including diabetes.
    Type: Application
    Filed: February 13, 2006
    Publication date: June 22, 2006
    Inventors: Keith Allen, Catherine Guenther, Russell Phillips, Qin Zhang, Helene Baribault
  • Transgenic mice containing retina-specific nuclear receptor gene disruptions
    Patent number: 6730821
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in genes, which are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: May 4, 2004
    Assignee: Deltagen, Inc.
    Inventor: Catherine Guenther
  • TRANSGENIC MICE CONTAINING RETINA-SPECIFIC NUCLEAR RECEPTOR GENE DISRUPTIONS
    Publication number: 20040040046
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in genes, which are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 16, 2001
    Publication date: February 26, 2004
    Inventor: Catherine Guenther
  • Kv3.3b potassium channel disruptions, compositions and methods related thereto
    Publication number: 20030131367
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a Kv3.3b gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: September 23, 2002
    Publication date: July 10, 2003
    Inventors: Catherine Guenther, Keith D. Allen, Qin Zhang
  • Proliferator-activated receptor disruptions, compositions and methods relating thereto
    Publication number: 20030046719
    Abstract: The present invention relates to compositions, including transgenic and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a PPAR gene. The present invention also provides methods for identifying agents that modulate PPAR expression and function, useful models, and potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: June 24, 2002
    Publication date: March 6, 2003
    Inventors: Keith D. Allen, Catherine Guenther, Russell Phillips
  • Transgenic mice containing NOR1 gene disruptions
    Publication number: 20020152492
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a NOR1 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: October 17, 2002
    Inventors: Catherine Guenther, Keith D. Allen
  • Transgenic mice containing retinoid X receptor interacting protein gene disruptions
    Publication number: 20020116731
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in the LXRB gene. Such transgenic mice are useful as models for disease, such as diabetes. The present invention is also directed to identifying agents that modulate LXRB gene function, and as potential treatments for various disease states and disease conditions, including diabetes.
    Type: Application
    Filed: December 10, 2001
    Publication date: August 22, 2002
    Inventors: Keith D. Allen, Catherine Guenther, Russell Phillips, Qin Zhang, Helene Baribault
  • Transgenic mice containing proliferator-activated receptor gene disruptions
    Publication number: 20020112256
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in proliferator-activated receptors. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 11, 2001
    Publication date: August 15, 2002
    Inventors: Keith D. Allen, Catherine Guenther, Russell Phillips
  • Transgenic mice containing RORgamma gene disruptions
    Publication number: 20020108138
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a ROR&ggr; gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: June 28, 2001
    Publication date: August 8, 2002
    Inventor: Catherine Guenther
  • Transgenic mice containing nuclear hormone receptor gene disruptions
    Publication number: 20020056146
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a nuclear hormone receptor gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: June 14, 2001
    Publication date: May 9, 2002
    Inventors: Catherine Guenther, Thomas J. Brennan