Abstract: A method of reducing scale on a surface, the method including: contacting (i) one or more biochelants; (ii) one or more organophosphorus compound; (iii) an optional enhancer and (iv) a solvent with the surface having one or more deposits comprising iron sulfide. A composition comprising: (i) a biochelant; (ii) an organophosphorus compound; (iii) an optional enhancer and (iv) a solvent. A method of servicing a wellbore disposed in a subterranean formation including: placing into the wellbore a fluid comprising a biochelant; (ii) an organophosphorus compound; (iii) an optional enhancer; and (iv) a solvent for a time period sufficient to reduce a level of iron sulfide deposits by at least about 10% wherein the optional enhancer comprises an amino alcohol.

Abstract: The present invention relates to a pharmaceutical combination comprising a KRAS G12C inhibitor and one or more therapeutic agents which is selected from an agent targeting the MARK pathway or an agent targeting parallel pathways; and pharmaceutical compositions comprising the same. The invention also relates to KRAS G12C inhibitors alone or said combinations for use in methods of treating a cancer or a tumor, in particular wherein the cancer or tumor is KRAS G12C mutant.

Abstract: Provided herein are single domain antibodies (sdAbs) configured for passing the blood brain barrier in a human or mammal brain. Methods of using such sdAbs are also described herein, such as methods of binding to brain cells, binding with and transporting other sdAbs with beneficial functionalities, binding to and transporting biochemical or pharmaceutical species with beneficial functionalities, and treating, diagnosing, or prophylactically treating a disease, malignancy, or condition.

Abstract: A detergent additive comprising (i) a biochelant; (ii) a ring-opener, and (iii) a solvent. A method of treating a contaminated surface comprising contacting a detergent and a detergent additive with the contaminated surface wherein the detergent additive comprises (i) a biochelant; (ii) a ring-opener, and (iii) a solvent.

Abstract: A semiconductor device includes a semiconductor substrate, a first module of circuitry formed on the semiconductor substrate, a second module of circuitry formed on the semiconductor substrate, and a communication ring that encircles the first module of circuitry. The communication ring includes an insulation material disposed over the semiconductor substrate, a plurality of electrical connectors disposed over the semiconductor substrate and extending across a width of the communication ring, and a conductive diffusion in the semiconductor substrate that encircles the first module of circuitry.

Abstract: An absorbent article includes bond seams that are positioned forwardly towards the article central longitudinal direction from the lateral-most side edges of the article, and which are aligned with the highest point of high-rise leg openings on the article. The absorbent article is conformable on both front and back panels, with the front panel being narrower in dimension than the back panel. The bond seams and leg openings can be seen on the front surface of the relaxed and flattened absorbent article. Such absorbent article may be manufactured along the article transverse direction by use of differential tension during manufacture, or differential retractive properties of elastic base materials.

Abstract: In one embodiment, a method includes accessing real-time content captured by a first user's client device, where the real-time content is captured at a first high quality and is one of a plurality of content frames in a real-time stream of content. The method includes downgrading the quality of the real-time content to a second lower quality for transmission to a second user and transmitting the downgraded content to the second user. The method includes determining, based on a request made by the second user, an area of interest of a subsequent real-time image, where the subsequent real-time image is at the first high quality, modifying the subsequent real-time image to focus on the area of interest, where the modified subsequent real-time image is at the first high quality, and downgrading and transmitting the modified subsequent real-time image for to the second user.

Abstract: An all-purpose drainage catheter which includes an all-purpose drainage catheter lumen, an extension tubing, a collection bag, a catheter hub, a Luer valve. The extension tubing inserted into the all-purpose drainage catheter lumen. The collection bag is fluidly coupled to the extension tubing. The Luer valve facilitates nephrostomy care so that when the all-purpose drainage catheter is in place urine flows from the renal pelvis into the all-purpose drainage catheter lumen, the extension tubing and the collection bag. The Luer valve employs a scalloped Luer-style male connector which, when screwed into the catheter hub, further allows urine to flow from the renal pelvis into the all-purpose drainage catheter lumen, the extension tubing and the collection bag. The all-purpose drainage catheter includes an outer catheter hub, an inner catheter hub coupled to the Luer valve at one end thereof and insertedly coupled to the outer catheter hub.

Abstract: Systems and methods are disclosed that provide for evaluating merchant business intelligence information. In certain embodiments, a system is disclosed to aggregate data relating to one or more merchants, customers, and/or transactions into a first data repository. The systems and methods receive a first request from a first client device, the first request including a parameter identifying one or more categories. The systems and methods determine that the first request is compatible with a data repository. The systems and methods the aggregated data of the data repository according to the parameter. The systems and methods also provide to a client device the filtered aggregated data.

Abstract: In an implementation, a mobile communications device includes a display device having touchscreen functionality, a keyboard having a plurality of physical keys that include a dedicated key and letter keys arranged according to a QWERTY layout, and one or more modules. The one or more modules are configured to output a user interface on the display device responsive to selection of the dedicated key, the user interface having a plurality of portions that are selectable via the touchscreen functionality to cause input of a respective one of a plurality of emoticons.

Abstract: In an implementation, a mobile communications device includes a display device having touchscreen functionality, a keyboard having a plurality of physical keys that include a dedicated key and letter keys arranged according to a QWERTY layout, and one or more modules. The one or more modules are configured to output a user interface on the display device responsive to selection of the dedicated key, the user interface having a plurality of portions that are selectable via the touchscreen functionality to cause input of a respective one of a plurality of emoticons.

Abstract: In an implementation, a mobile communications device includes a display device having touchscreen functionality, a keyboard having a plurality of physical keys that include a dedicated key and letter keys arranged according to a QWERTY layout, and one or more modules. The one or more modules are configured to output a user interface on the display device responsive to selection of the dedicated key, the user interface having a plurality of portions that are selectable via the touchscreen functionality to cause input of a respective one of a plurality of emoticons.

Abstract: In an implementation, a mobile communications device includes a display device having touchscreen functionality, a keyboard having a plurality of physical keys that include a dedicated key and letter keys arranged according to a QWERTY layout, and one or more modules. The one or more modules are configured to output a user interface on the display device responsive to selection of the dedicated key, the user interface having a plurality of portions that are selectable via the touchscreen functionality to cause input of a respective one of a plurality of emoticons.

Abstract: In an implementation, a mobile communications device includes a display device having touchscreen functionality, a keyboard having a plurality of physical keys that include a dedicated key and letter keys arranged according to a QWERTY layout, and one or more modules. The one or more modules are configured to output a user interface on the display device responsive to selection of the dedicated key, the user interface having a plurality of portions that are selectable via the touchscreen functionality to cause input of a respective one of a plurality of emoticons.

Abstract: In an implementation, a mobile communications device includes a display device having touchscreen functionality, a keyboard having a plurality of physical keys that include a dedicated key and letter keys arranged according to a QWERTY layout, and one or more modules. The one or more modules are configured to output a user interface on the display device responsive to selection of the dedicated key, the user interface having a plurality of portions that are selectable via the touchscreen functionality to cause input of a respective one of a plurality of emoticons.