Patents by Inventor Catherine Lucy STACE

Catherine Lucy STACE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP
    Publication number: 20240082410
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Application
    Filed: May 11, 2023
    Publication date: March 14, 2024
    Inventors: Daniel Paul TEUFEL, Catherine Lucy STACE, Silvia PAVAN, Edward WALKER, Leonardo BALDASSARRE
  • Bicyclic peptide ligands specific for MT1-MMP
    Patent number: 11672868
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: June 13, 2023
    Assignee: BicycleRD Limited
    Inventors: Daniel Paul Teufel, Catherine Lucy Stace, Silvia Pavan, Edward Walker, Leonardo Baldassarre
  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP
    Publication number: 20220023432
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Application
    Filed: July 22, 2021
    Publication date: January 27, 2022
    Inventors: Daniel Paul TEUFEL, Catherine Lucy Stace, Silvia Pavan, Edward Walker, Leonardo Baldassarre
  • Bicyclic peptide ligands specific for MT1-MMP
    Patent number: 11103591
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: August 31, 2021
    Assignee: BicycleRD Limited
    Inventors: Daniel Paul Teufel, Catherine Lucy Stace, Silvia Pavan, Edward Walker, Leonardo Baldassarre
  • Bicyclic peptide ligands specific for MT1-MMP
    Patent number: 10792368
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: October 6, 2020
    Assignee: BicycleRD Limited
    Inventors: Daniel Paul Teufel, Catherine Lucy Stace, Silvia Pavan, Edward Walker, Leonardo Baldassarre
  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP
    Publication number: 20200289657
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Application
    Filed: April 2, 2020
    Publication date: September 17, 2020
    Inventors: Daniel Paul Teufel, Catherine Lucy STACE, Silvia PAVAN, Edward WALKER, Leonardo BALDASSARRE
  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP
    Publication number: 20200171161
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Application
    Filed: December 6, 2019
    Publication date: June 4, 2020
    Inventors: Daniel Paul Teufel, Catherine Lucy Stace, Silvia Pavan, Edward Walker, Leonardo Baldassarre
  • Bicyclic peptide ligands specific for MT1-MMP
    Patent number: 10532106
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: January 14, 2020
    Assignee: BICYCLERD LIMITED
    Inventors: Daniel Paul Teufel, Catherine Lucy Stace, Silvia Pavan, Edward Walker, Leonardo Baldassare
  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP
    Publication number: 20180280525
    Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP).The invention also describes drug conjugates comprising said peptides,conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
    Type: Application
    Filed: October 29, 2015
    Publication date: October 4, 2018
    Inventors: Daniel Paul TEUFEL, Catherine Lucy STACE, Silvia PAVAN, Edward WALKER, Leonardo BALDASSARRE