Patents by Inventor Catherine M. Grgicak

Catherine M. Grgicak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220270712
    Abstract: Systems and methods of the present disclosure enable automated analyses of a biological sample using a processing system by receiving signal profiles of each allele of a set of cells in the sample. A set of allele vectors are determined based on a mapping of the magnitude of the measurement of each signal profile at each locus to an index location. A set of cell vectors is generated by concatenating each allele vector of each cell. A cluster model is utilized to generate clusters of the signal profiles based on the set of cell vectors to represent contributors. A first likelihood of a target contributor matching a contributor and a second likelihood of the target contributor not matching any contributor are determined by comparing the target signal profile to each cluster. A likelihood ratio is determined from a ratio of the first likelihood and the second likelihood.
    Type: Application
    Filed: February 11, 2022
    Publication date: August 25, 2022
    Inventors: Catherine M. Grgicak, Desmond S. Lun, Kenneth R. Duffy
  • Patent number: 10504614
    Abstract: Computerized analysis methods and systems to implement the computerized analysis methods are disclosed herein. Specifically, the present disclosure relates to systems and methods for determining an unknown characteristic of a sample.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: December 10, 2019
    Assignees: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, TRUSTEES OF BOSTON UNIVERSITY, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Catherine M. Grgicak, Desmond S. Lun, Muriel Medard, Harish Swaminathan
  • Publication number: 20160239606
    Abstract: Computerized analysis methods and systems to implement the computerized analysis methods are disclosed herein. Specifically, the present disclosure relates to systems and methods for determining an unknown characteristic of a sample.
    Type: Application
    Filed: October 7, 2014
    Publication date: August 18, 2016
    Inventors: Catherine M. Grgicak, Desmond S. Lun, Muriel Medard, Harish Swaminathan