Patents by Inventor Catherine Matthies

Catherine Matthies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8436049
    Abstract: Methods are provided herein for treatment of myotonic dystrophy and other toxic RNA diseases in a subject. In some examples, the method comprises administration of a compound that binds a nucleotide repeat expansion in a ribonucleic acid molecule, thereby treating the disease. In additional examples, the method comprises administration of a compound that disrupts binding of muscleblind-like proteins to an RNA nucleotide repeat expansion. Compounds for use in the disclosed method include pentamidine or heptamidine or derivatives thereof. Representative compounds are described herein.
    Type: Grant
    Filed: February 20, 2009
    Date of Patent: May 7, 2013
    Assignee: State of Oregon Acting By and Through the State Board of Higher Education on behalf of the University of Oregon
    Inventors: John Andrew Berglund, M. Bryan Warf, Catherine Matthys, Michael M. Haley, Cameron L. Hilton
  • Publication number: 20100323993
    Abstract: Methods are provided herein for treatment of myotonic dystrophy and other toxic RNA diseases in a subject. In some examples, the method comprises administration of a compound that binds a nucleotide repeat expansion in a ribonucleic acid molecule, thereby treating the disease. In additional examples, the method comprises administration of a compound that disrupts binding of muscleblind-like proteins to an RNA nucleotide repeat expansion. Compounds for use in the disclosed method include pentamidine or heptamidine or derivatives thereof. Representative compounds are described herein.
    Type: Application
    Filed: February 20, 2009
    Publication date: December 23, 2010
    Inventors: John Andrew Berglund, Bryan M. Warf, Catherine Matthys, Michael M. Haley, Cameron L. Hilton
  • Patent number: D434369
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: November 28, 2000
    Inventor: Catherine Matthies