Patents by Inventor Catherine May Morris

Catherine May Morris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell penetrating peptides for intracellular delivery of molecules
    Patent number: 7943581
    Abstract: The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8(SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
    Type: Grant
    Filed: December 30, 2008
    Date of Patent: May 17, 2011
    Assignees: Centre National de laRecherche de la Recherche, AFFYMETRIX, Inc.
    Inventors: Gilles Divita, Frederic Heitz, Catherine May Morris, Gudrun Aldrian-Herrada
  • INHIBITORS OF HIV REPLICATION AND METHOD OF TREATMENT OF HIV INFECTIONS
    Publication number: 20110064793
    Abstract: The invention is drawn to a novel class of drugs directed against HIV, comprising a peptide or analog comprising a decapeptide, said decapeptide containing (from N-terminus to the C-terminus) a basic amino acid in position 1, an acidic amino acid in positions 2 and 5, and a tryptophan in positions 4, 7, and 8, and to a method of treatment of HIV infections, in particular multidrug-resistant HIV infections.
    Type: Application
    Filed: August 16, 2010
    Publication date: March 17, 2011
    Applicant: Centre National De La Recherche Scientifique (C.N.R.S.)
    Inventors: Christian DeVaux, Véronique Hebmann, Gilles Divita, Frédéric Heitz, Catherine May Morris, Jean Mery, Roger S. Goody
  • Antiviral peptides obtained from the tryptophan-rich hydrophobic cluster of the HIV-1 reverse transcriptase
    Patent number: 7790171
    Abstract: The invention is drawn to a novel class of drugs directed against HIV, comprising a peptide or analog comprising a decapeptide, said decapeptide containing (from N-terminus to the C-terminus) a basic amino acid in position 1, an acidic amino acid in positions 2 and 5, and a tryptophan in positions 4, 7, and 8, and to a method of treatment of HIV infections, in particular multidrug-resistant HIV infections.
    Type: Grant
    Filed: August 25, 2000
    Date of Patent: September 7, 2010
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Christian Devaux, Véronique Hebmann, Gilles Divita, Frédéric Heitz, Catherine May Morris, Jean Mery, Roger S. Goody
  • Cell penetrating peptides for intracellular delivery of molecules
    Patent number: 7579318
    Abstract: The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: August 25, 2009
    Assignees: Centre de la Recherche de la Scientifique, Panomics, Inc.
    Inventors: Gilles Divita, Frédéric Heitz, Catherine May Morris, Gudrun Aldrian-Herrada
  • CELL PENETRATING PEPTIDES FOR INTRACELLULAR DELIVERY OF MOLECULES
    Publication number: 20090156503
    Abstract: The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8(SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
    Type: Application
    Filed: December 30, 2008
    Publication date: June 18, 2009
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENT, GENOSPECTRA, INC.
    Inventors: GILLES DIVITA, FREDERIC HEITZ, CATHERINE MAY MORRIS, GUDRUN ALDRIAN-HERRADA