Patents by Inventor Catherine O'CONNELL
Catherine O'CONNELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11459620Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium subsp. paratuberculosis from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.Type: GrantFiled: December 6, 2019Date of Patent: October 4, 2022Assignee: Life Technologies CorporationInventors: Yongmei (Alexis) Ji, Pius Brzoska, Angela Burrell, Craig Cummings, Catherine O'Connell
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Publication number: 20200095626Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium subsp. paratuberculosis from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.Type: ApplicationFiled: December 6, 2019Publication date: March 26, 2020Inventors: Yongmei (Alexis) JI, Pius BRZOSKA, Angela BURRELL, Craig CUMMINGS, Catherine O'CONNELL
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Patent number: 10513741Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium subsp. paratuberculosis from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.Type: GrantFiled: February 8, 2018Date of Patent: December 24, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Yongmei (Alexis) Ji, Pius Brzoska, Angela Burrell, Craig Cummings, Catherine O'Connell
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Patent number: 10184152Abstract: Methods are provided herein for determining the likelihood that a subject, such as an asymptomatic subject, has chlamydial pelvic inflammatory disease. In some embodiments, the method can determine the likelihood that a pharmaceutical agent is effective for treating a subject that has chlamydial pelvic inflammatory disease. In other specific non-limiting examples, the method predicts endometritis and elevated pathogen burden. The subject is a female, such as a human female.Type: GrantFiled: April 16, 2015Date of Patent: January 22, 2019Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: Catherine O'Connell, Toni Darville, Xiaojing Zheng
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Publication number: 20180237830Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium subsp. paratuberculosis from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.Type: ApplicationFiled: February 8, 2018Publication date: August 23, 2018Inventors: Yongmei (Alexis) JI, Pius BRZOSKA, Angela BURRELL, Craig CUMMINGS, Catherine O'CONNELL
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Patent number: 9926609Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium subsp. paratuberculosis from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.Type: GrantFiled: December 22, 2015Date of Patent: March 27, 2018Assignee: Life Technologies CorporationInventors: Yongmei Ji, Pius Brzoska, Angela Burrell, Craig Cummings, Catherine O'Connell
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Publication number: 20170183732Abstract: Methods are provided herein for determining the likelihood that a subject, such as an asymptomatic subject, has chlamydial pelvic inflammatory disease. In some embodiments, the method can determine the likelihood that a pharmaceutical agent is effective for treating a subject that has chlamydial pelvic inflammatory disease. In other specific non-limiting examples, the method predicts endometritis and elevated pathogen burden. The subject is a female, such as a human female.Type: ApplicationFiled: April 16, 2015Publication date: June 29, 2017Applicant: University of Pittsburgh - Of the Commonwealth System of Higher EducationInventors: Catherine O'Connell, Toni Darville, Xiaojing Zheng
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Publication number: 20160186242Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium subsp. paratuberculosis from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.Type: ApplicationFiled: December 22, 2015Publication date: June 30, 2016Inventors: Yongmei Ji, Pius Brzoska, Angela Burrell, Craig Cummings, Catherine O'Connell
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Patent number: 9334542Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of a non-Mycobacterium avium subsp. paratuberculosis (non-MAP) organism, wherein a non-MAP organism is a Mycobacterium avium complex (MAC) organism that does not belong to the Mycobacterium avium subsp. paratuberculosis (MAP) organism, from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample. Exemplary non-MAP organisms including M. avium subsp. avium (MAA), M. avium subsp. hominissuis (MAH), and M. avium subsp. silvaticum (MAS) can be detected by the present compositions, kits and methods.Type: GrantFiled: March 5, 2013Date of Patent: May 10, 2016Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Craig Cummings, Pius Brzoska, Angela Burrell, Catherine O'Connell
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Patent number: 9255299Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium subsp. paratuberculosis from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.Type: GrantFiled: March 5, 2013Date of Patent: February 9, 2016Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Yongmei Ji, Pius Brzoska, Angela Burrell, Craig Cummings, Catherine O'Connell
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Publication number: 20140272940Abstract: The present disclosure, in some embodiments, relates to compositions and methods for detection of multiple target nucleic acid sequences by a single nucleic acid amplification based assay (e.g. PCR). Compositions comprising two or more primers are described for multiple target nucleic acid detection. Methods for differential detection of microorganisms (including strains/serovars/subtypes thereof) and cell types comprise a single step method to detect a signature of target nucleic acid sequences comprising: two, three or more target nucleic acids that are uniquely present in a microorganism/strain/serovar/subtype and/or cell and absent in other closely related organisms/cells. Embodiments relate to methods of diagnosis of diseases or conditions that can be detected by detecting the presence of two or more nucleic acid target markers.Type: ApplicationFiled: March 12, 2014Publication date: September 18, 2014Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Wayne Ge, Craig Cummings, Darcy Myers, Quoc Hoang, Catherine O'Connell, Maxim Brevnov, Daniel Kephart
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Publication number: 20140005061Abstract: The present disclosure describes compositions, methods and kits for detection of one or multiple microorganism contaminants in samples. Some embodiments relate to detecting one or more microorganisms producing virulence factors such as shiga toxin stx1 and stx2 and eae. Some embodiments relate to detection of STEC microorganisms including an E. coli O26, an E. coli O45, an E. coli O103, an E. coli O111, an E. coli O121 or an E. coli O145. In some embodiments, compositions, methods and kits can detect and identify individual serotypes of shiga toxin producing microorganisms. Workflows for multiple microbe detection and identification are also described.Type: ApplicationFiled: March 8, 2013Publication date: January 2, 2014Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Robert TEBBS, Craig Cummings, Pius Brzoska, Sharon Matheny, Catherine O'Connell, Manohar Furtado, Nikolay Sergeev, Maxim Brevnov
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Publication number: 20130260375Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of a non-Mycobacterium avium subsp. paratuberculosis (non-MAP) organism, wherein a non-MAP organism is a Mycobacterium avium complex (MAC) organism that does not belong to the Mycobacterium avium subsp. paratuberculosis (MAP) organism, from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample. Exemplary non-MAP organisms including M. avium subsp. avium (MAA), M. avium subsp. hominissuis (MAH), and M. avium subsp. silvaticum (MAS) can be detected by the present compositions, kits and methods.Type: ApplicationFiled: March 5, 2013Publication date: October 3, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Craig CUMMINGS, Pius Brzoska, Angela Burrell, Catherine O'Connell
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Publication number: 20130260374Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of Mycobacterium avium subsp. paratuberculosis from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.Type: ApplicationFiled: March 5, 2013Publication date: October 3, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Yongmei JI, Pius Brzoska, Angela Burrell, Craig Cummings, Catherine O'Connell
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Publication number: 20130122505Abstract: The present teachings describe compositions, methods and kits for detection of one or multiple microorganism contaminants in samples. Some embodiments relate to detecting one or more microorganisms producing virulence factors such as a shiga toxin (stx) or an eae. In some embodiments, compositions, methods and kits can detect and identify individual strains and serotypes of shiga toxin producing microorganisms. Some embodiments describe compositions, methods and kits for detecting STEC microbes. Workflows for multiple microbe detection and identification are also described.Type: ApplicationFiled: August 24, 2012Publication date: May 16, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Robert TEBBS, Craig Cummings, Pius Brzoska, Sharon Matheny, Catherine O'Connell, Manohar Furtado, Rixun Fang, Olga Petrauskene, Sueh-Ning Liew, Michael Schumaker
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Publication number: 20130122484Abstract: The present specification relates to methods and kits for detection of animals that are persistently infected (PI) with a Bovine Viral Diarrhea Virus (BVDV) and/or transiently infected (TI) with BVDV. Some embodiments describe methods to distinguish a PI animal from a TI animal using a single one-time testing protocol.Type: ApplicationFiled: October 1, 2012Publication date: May 16, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: John EL-ATTRACHE, Quoc HOANG, Catherine O'CONNELL