Patents by Inventor Catherine Sautes-Fridman

Catherine Sautes-Fridman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132974
    Abstract: Complement components form a plasma innate immune cascade but could also serve as multitasking proteins, as they have functions beyond this system. Here, we show that complement FH is locally expressed by multiple types of human tumors. We provide a paradigm shift for the impact of FH on cancer progression, showing a previously unrecognized, intracellular function of FH outside the complement cascade, while the canonical, complement-regulatory function had no effect. Int-FH served as a driver of the proliferation and migration of ccRCC and lung ADK cells but not of normal cells or lung SCC cells. The presence of int-FH staining in tumor cells indicated poor prognosis for ccRCC and lung ADK.
    Type: Application
    Filed: February 11, 2022
    Publication date: April 25, 2024
    Inventors: Lubka ROUMENINA, Marie DAUGAN, Margot REVEL, Isabelle CREMER, Catherine SAUTES-FRIDMAN, Wolf Herman FRIDMAN
  • Patent number: 11385231
    Abstract: The present invention relates to methods for predicting the survival time of patients suffering from a lung cancer.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: July 12, 2022
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE SCIENTIFIQUE), UNIVERSITE DE PARIS, SORBONNE UNIVERSITE, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP)
    Inventors: Marie-Caroline Dieu-Nosjean, Wolf Herdman Fridman, Catherine Sautes-Fridman, Priyanka Devi
  • Publication number: 20200041519
    Abstract: The present invention relates to an in vitro method for the prognosis of the survival time of a patient suffering from a solid cancer, comprising the quantification of the cell density of follicular B cells present in tumor-induced lymphoid structures from said patient, wherein a high density of follicular B cells indicates that the patient has a favorable prognosis and a low density of follicular B cells indicates that the patient has a poor prognosis.
    Type: Application
    Filed: September 17, 2019
    Publication date: February 6, 2020
    Inventors: Marie-Caroline Dieu-Nosjean, Wolf Herve Fridman, Romain Remark, Catherine Sautes-Fridman
  • Publication number: 20180252720
    Abstract: The present invention relates to methods for predicting the survival time of patients suffering from a lung cancer.
    Type: Application
    Filed: August 26, 2016
    Publication date: September 6, 2018
    Inventors: Marie-Caroline DIEU-NOSJEAN, Wolf Herdman FRIDMAN, Catherine SAUTES-FRIDMAN, Priyanka DEVI
  • Patent number: 9851357
    Abstract: The present invention relates to an in vitro method for the prognosis of survival of a patient suffering from a solid cancer, comprising the quantification of the cell density of CD8+ cells and DC-LAMP+ dendritic cells present in a tumor tissue sample from said patient, wherein a high density of CD8+ cells and DC-LAMP+ dendritic cells indicates that the patient has a favorable prognosis, a high density of CD8+ cells and a low density of DC-LAMP+ dendritic cells indicates that the patient has a poor prognosis, and a low density of CD8+ cells and DC-LAMP+ dendritic cells indicates that the patient has the worst prognosis.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: December 26, 2017
    Assignees: INSERM (INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE PARIS DESCARTES, UNIVERSITE PIERRE ET MARIE CURIE (PARIS6), ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
    Inventors: Catherine Sautes-Fridman, Wolf-Herve Fridman, Marie-Caroline Dieu-Nosjean, Jeremy Goc
  • Publication number: 20160146820
    Abstract: The present invention relates to an in vitro method for the prognosis of survival of a patient suffering from a solid cancer, comprising the quantification of the cell density of CD8+ cells and DC-LAMP+ dendritic cells present in a tumor tissue sample from said patient, wherein a high density of CD8+ cells and DC-LAMP+ dendritic cells indicates that the patient has a favorable prognosis, a high density of CD8+ cells and a low density of DC-LAMP+ dendritic cells indicates that the patient has a poor prognosis, and a low density of CD8+ cells and DC-LAMP+ dendritic cells indicates that the patient has the worst prognosis.
    Type: Application
    Filed: July 11, 2014
    Publication date: May 26, 2016
    Inventors: Catherine Sautes-Fridman, Wolf-Herve Fridman, Marie-Caroline Dieu-Nosjean, Jeremy Goc
  • Publication number: 20150004253
    Abstract: The present invention relates to an in vitro method for the prognosis of the survival time of a patient suffering from a solid cancer, comprising the quantification of the cell density of follicular B cells present in tumor-induced lymphoid structures from said patient, wherein a high density of follicular B cells indicates that the patient has a favorable prognosis and a low density of follicular B cells indicates that the patient has a poor prognosis.
    Type: Application
    Filed: January 21, 2013
    Publication date: January 1, 2015
    Inventors: Marie-Caroline Dieu-Nosjean, Wolf Herve Fridman, Romain Remark, Catherine Sautes-Fridman