Abstract: The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.

Abstract: The invention describes peptide ligands specific for human plasma Kallikrein.

Abstract: The invention provides oxazinyl isoflavonoid compounds and compositions containing same, methods for their preparation and their use as therapeutic agents particularly as cardioprotective, anti-inflammatory, anti-oxidant and chemotherapeutic agents.

Abstract: Anti-inflammatory modalities are described with reference to select isoflavonoid compounds, compositions containing same and the use of said compounds and/or compositions in treatment, particularly for the treatment of inflammatory diseases and related conditions.

Abstract: 2-Substituted isoflavonoid compounds and pharmaceutical compositions containing same are useful as anti-inflammatory agents and antioxidants and for the treatment of related diseases and conditions.

Abstract: The invention provides oxazinyl isoflavonoid compounds and compositions containing same, methods for their preparation and their use as therapeutic agents particularly as cardioprotective, anti-inflammatory, anti-oxidant and chemotherapeutic agents.

Abstract: Anti-inflammatory modalities are described with reference to select isoflavonoid compounds, compositions containing same and the use of said compounds and/or compositions in treatment, particularly for the treatment of inflammatory diseases and related conditions.

Abstract: A Web user interface session is initialized in such a way as to allow certain contextual environmental information associated with a user, including session properties such as user name, user role, and locale, to be shared between all applications invoked during the web user interface session. Application programming interfaces (APIs) are disclosed that provide access to the environmental information for both common gateway interface (CGI) programs as well as Java applets. The sharing of the environmental information between session applications allows a consistent user interface to be presented to the user during the session.

Abstract: A Web user interface session is initialized in such a way as to allow certain contextual environmental information associated with a user, including session properties such as user name, user role, and locale, to be shared between all applications invoked during the web user interface session. Application programming interfaces (APIs) are disclosed that provide access to the environmental information for both common gateway interface (CGI) programs as well as Java applets. The sharing of the environmental information between session applications allows a consistent user interface to be presented to the user during the session.

Abstract: A Web user interface session is initialized in such a way as to allow certain contextual environmental information associated with a user, including session properties such as user name, user role, and locale, to be shared between all applications invoked during the web user interface session. Application programming interfaces (APIs) are disclosed that provide access to the environmental information for both common gateway interface (CGI) programs as well as Java applets. The sharing of the environmental information between session applications allows a consistent user interface to be presented to the user during the session.