Patents by Inventor Cathie KESSLER

Cathie KESSLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220016368
    Abstract: An apparatus and method for controlling the end tidal partial pressure of a gas X in a subject's lung, and to the use of such an apparatus and method for research, diagnostic and therapeutic purposes, wherein the method consists of: -obtaining input of a series of logistically attainable PetX values for a series of respective breaths: -determining an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX for each of said respective breaths; and controlling a gas delivery device to deliver the amount of gas in a volume of gas delivered to the subject in each of said respective breaths to target the respective PetX for that breath.
    Type: Application
    Filed: July 28, 2021
    Publication date: January 20, 2022
    Inventors: Michael KLEIN, Joseph FISHER, James DUFFIN, Marat SLESSAREV, Cathie KESSLER, Shoji ITO, Olivia SOBCZYK, Anne BATTISTI-CHARBONNEY, Daniel Michael MANDELL, David MIKULIS
  • Patent number: 11077266
    Abstract: An apparatus and method for controlling the end tidal partial pressure of a gas X in a subject's lung, and to the use of such an apparatus and method for research, diagnostic and therapeutic purposes, wherein the method consists of: —obtaining input of a series of logistically attainable PetX values for a series of respective breaths: —determining an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX for each of said respective breaths: and—controlling a gas delivery device to deliver the amount of gas in a volume of gas delivered to the subject in each of said respective breaths to target the respective PetX for that breath.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: August 3, 2021
    Assignee: THORNHILL SCIENTIFIC INC.
    Inventors: Michael Klein, Joseph Fisher, James Duffin, Marat Slessarev, Cathie Kessler, Shoji Ito, Olivia Sobczyk, Anne Battisti-Charbonney, Daniel Michael Mandell
  • Patent number: 10850052
    Abstract: A processor obtains input of a logistically attainable end tidal partial pressure of gas X (PetX[i]T) for one or more respective breaths [i] and input of a prospective computation of an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX[i]T for a respective breath [i] using inputs required to utilize a mass balance relationship, wherein one or more values required to control the amount of gas X in a volume of gas delivered to the subject is output from an expression of the mass balance relationship. The mass balance relationship is expressed in a form which takes into account (prospectively), for a respective breath [i], the amount of gas X in the capillaries surrounding the alveoli and the amount of gas X in the alveoli, optionally based on a model of the lung which accounts for those sub-volumes of gas in the lung which substantially affect the alveolar gas X concentration affecting mass transfer.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: December 1, 2020
    Assignee: THORNHILL SCIENTIFIC INC.
    Inventors: Michael Klein, Joseph Fisher, James Duffin, Marat Slessarev, Cathie Kessler, Shoji Ito
  • Publication number: 20180311454
    Abstract: An apparatus and method for controlling the end tidal partial pressure of a gas X in a subject's lung, and to the use of such an apparatus and method for research, diagnostic and therapeutic purposes, wherein the method consists of: obtaining input of a series of logistically attainable PetX values for a series of respective breaths: determining an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX for each of said respective breaths: and controlling a gas delivery device to deliver the amount of gas in a volume of gas delivered to the subject in each of said respective breaths to target the respective PetX for that breath.
    Type: Application
    Filed: February 23, 2018
    Publication date: November 1, 2018
    Inventors: Michael Klein, Joseph Fisher, James Duffin, Marat Slessarev, Cathie Kessler, Shoji Ito, Olivia Sobczyk, Anne Battisti-Charbonney, Daniel Michael Mandell
  • Publication number: 20170361042
    Abstract: A processor obtains input of a logistically attainable end tidal partial pressure of gas X (PetX[i]T) for one or more respective breaths [i] and input of a prospective computation of an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX[i]T for a respective breath [i] using inputs required to utilize a mass balance relationship, wherein one or more values required to control the amount of gas X in a volume of gas delivered to the subject is output from an expression of the mass balance relationship. The mass balance relationship is expressed in a form which takes into account (prospectively), for a respective breath [i], the amount of gas X in the capillaries surrounding the alveoli and the amount of gas X in the alveoli, optionally based on a model of the lung which accounts for those sub-volumes of gas in the lung which substantially affect the alveolar gas X concentration affecting mass transfer.
    Type: Application
    Filed: May 3, 2017
    Publication date: December 21, 2017
    Inventors: Michael Klein, Joseph Fisher, James Duffin, Marat Slessarev, Cathie Kessler, Shoji Ito
  • Publication number: 20150114394
    Abstract: An apparatus and method for controlling the end tidal partial pressure of a gas X in a subject's lung, and to the use of such an apparatus and method for research, diagnostic and therapeutic purposes, wherein the method consists of: obtaining input of a series of logistically attainable PetX values for a series of respective breaths: determining an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX for each of said respective breaths: and controlling a gas delivery device to deliver the amount of gas in a volume of gas delivered to the subject in each of said respective breaths to target the respective PetX for that breath.
    Type: Application
    Filed: April 30, 2013
    Publication date: April 30, 2015
    Inventors: Michael Klein, Joseph Fisher, James Duffin, Marat Slessarev, Cathie Kessler, Shoji Ito, Olivia Sobczyk, Anne Battisti-Charbonney, Daniel Michael Mandell
  • Publication number: 20140311491
    Abstract: A processor obtains input of a logistically attainable end tidal partial pressure of gas X (PetX[i]T) for one or more respective breaths [i] and input of a prospective computation of an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX[i]T for a respective breath [i] using inputs required to utilize a mass balance relationship, wherein one or more values required to control the amount of gas X in a volume of gas delivered to the subject is output from an expression of the mass balance relationship. The mass balance relationship is expressed in a form which takes into account (prospectively), for a respective breath [i], the amount of gas X in the capillaries surrounding the alveoli and the amount of gas X in the alveoli, optionally based on a model of the lung which accounts for those sub-volumes of gas in the lung which substantially affect the alveolar gas X concentration affecting mass transfer.
    Type: Application
    Filed: December 5, 2012
    Publication date: October 23, 2014
    Inventors: Michael KLEIN, Joseph FISHER, James DUFFIN, Marat SLESSAREV, Cathie KESSLER, Shoji ITO