Abstract: The present disclosure describes devices, systems, and methods for intravascularly delivering an intravascular device to a targeted cardiac valve. In one aspect, a medical device includes a body and a plurality of positional markers positioned on the body, the plurality of positional markers being defined in part by at least one cutout and having at least one parameter selected such that the plurality of positional markers vibrates, in response to an ultrasound signal, at a resonant frequency.

Abstract: A prosthetic heart valve includes collapsible and expandable inner and outer frames. The outer frame engages native heart valve annulus tissue, with an atrial portion, a ventricle portion, and a narrowed waist portion between the two. The inner frame is positioned radially inward of the outer frame. The outer frame includes a plurality of outer coupling arms having a first end coupled to the outer frame and a second free end, and the inner frame includes a plurality of inner coupling arms having a first end coupled to the inner frame and a second free end. A prosthetic valve assembly is disposed within the inner frame. The first end of the inner and outer coupling arms each include two struts. The coupling arms extend toward each other and the second free ends of the coupling arms are coupled to each other to couple the outer frame to the inner frame.

Abstract: A prosthetic heart valve includes an outer frame having an atrial portion, a ventricle portion, a narrowed waist portion between the atrial portion and the ventricle portion, and a plurality of outer coupling arms having a first end coupled to the outer frame and a second free end. An inner frame is positioned radially inward of the outer frame and includes a plurality of inner coupling arms having a first end coupled to the inner frame and a second free end, the first ends of the inner coupling arms coupled to the inner frame at a location substantially equidistant between an inflow end of the inner frame and an outflow end of the inner frame. The second free ends of the outer coupling arms are coupled to the second free ends of the inner coupling arms to couple the outer frame to the inner frame.

Abstract: The present invention is an improved apparatus for holding and maneuvering a valve during preparation and attachment to patient. The present invention is particularly useful for increased visibility of the prosthetic valve and the sewing ring to prevent suture entanglement. The present invention is used most effectively with mitral valves having commissure posts on the outflow side of the valve structure but may be used with other valve configurations. The present invention spaces the handle attachment from the valve for improved visibility of the sewing ring and the outlet end of the valve during attachment. The present invention is adapted to safely bend the commissure posts inward at the tips while preventing crashing the commissure posts into each other causing damage. The new holder prevents suture remnants left in a patient by a designed break point for the holder suture.

Abstract: This invention relates to a system and apparatus for retaining a prosthetic valve in a valve pocket suspended in a sealed container to protect from damage and contamination during shipment, handling and storage. The apparatus is an easy to open container having remote fill ports for adding a sterile liquid after enclosing the valve inside. A tamper evident seal is provided having a novel configuration to detect prior opening of the container. The apparatus includes an assembly having a shelf that is provided in a variety of configurations. The shelf has a mitral valve configuration and an aortic valve configuration. The shelf is selected based on the valve configurations and size. The system is easily assembled having a single variable component to adapt to a particular prosthetic valve to be stored. The present invention provides an apparatus for eliminating the need for direct attachment of the valve serial tag to the valve.