Patents by Inventor Cathy Ivarie

Cathy Ivarie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human skin equivalents expressing exogenous polypeptides
    Publication number: 20060257383
    Abstract: The present invention relates generally to compositions for wound healing. More specifically, the present invention provides human skin equivalents engineered to express exogenous proteinase inhibitor polypeptides (e.g., TIMP-1 polypeptides) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Application
    Filed: March 1, 2006
    Publication date: November 16, 2006
    Applicant: Stratatech Corporation
    Inventors: B. Allen-Hoffmann, Cathy Ivarie, Christina Thomas-Virnig
  • Skin substitutes with improved purity
    Publication number: 20060258001
    Abstract: The present invention relates to in vitro cultured skin substitutes. In particular, the present invention relates to compositions and methods for the development of cultured skin substitutes using NIKS cells.
    Type: Application
    Filed: March 15, 2006
    Publication date: November 16, 2006
    Applicant: Stratatech Corporation
    Inventors: B. Allen-Hoffmann, Cathy Ivarie, John Centanni
  • Skin substitutes and uses thereof
    Publication number: 20050226853
    Abstract: The present invention relates to in vitro cultured skin substitutes, and in particular to improved methods for organotypic culture of skin substitutes. In some embodiments, the dermal equivalent of the skin substitute is lifted to air interface of the culture prior to seeding with keratinocytes. In other embodiments, increased concentrations of collagen are used to form the dermal equivalent. In still other embodiments, optimized media are utilized to maintain the skin equivalents.
    Type: Application
    Filed: December 7, 2004
    Publication date: October 13, 2005
    Inventors: Paul Conrad, Cathy Ivarie, Lynn Allen-Hoffmann