Abstract: CTI servers capable of communicating with multiple clients and methods of operating the same are disclosed. An example system includes a client handler to receive messages from the multiple clients, a message handler to change the format of the messages, a queue to store messages, an interface to a telephony network, a data processor to generate responses to messages, and a CTI driver to retrieve messages from the queue and pass the retrieved messages to the data processor, and a data storage to store data associated with the messages.