Patents by Inventor Cayetano von Kobbe

Cayetano von Kobbe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccines for the treatment of neoplasias from viral capsids of birnavirus containing antigens of the human papillomavirus
    Patent number: 8951534
    Abstract: The invention relates to therapeutic vaccines for the treatment of neoplasias caused by the human papillomavirus (HPV). In particular, the vaccines of the present invention are formed by chimeric virus-like capsids of birnavirus containing papillomavirus antigens.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: February 10, 2015
    Assignee: Chimera Pharma, S.L.U
    Inventors: Thomas Zurcher, Cayetano Von Kobbe, Juan J. Bernal, Ignacio Jiménez Torres, Gloria Calderita Lucas, Margarita Rodriguez Garcia, Ana Garzon Gutierrez, Virginia Gondar Sousa E Silva, Arcadio García De Castro, Irene Pino De La Huerga
  • Chimeric fusion proteins and virus like particles from Birnavirus VP2
    Patent number: 8784827
    Abstract: The field of the invention refers to chimeric Virus Like Particles (VLP) derived from Birnavirus chimeric VP2 protein. In particular, the invention refers to chimeric VP2 fusion proteins which incorporate insertions and/or substitutions with one or more amino acids or particular peptide of interest while maintaining the capacity to assemble in the form of VLP. The invention identifies particular insertion and/or substitutions sites within VP2 P loop regions and outside said P loop regions. The invention also incorporates methods for the identification of preferred insertion and substitution sites within VP2 for the incorporation of particular amino acids and peptides of interest. The resulting chimeric VLP are of interest in the design of therapeutic and prophylactic vaccines as well as in the design of drug delivery systems, carriers for DNA and RNA in gene therapy, as targeted agents, in the development of antitoxins, and as diagnostic reagents.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: July 22, 2014
    Assignee: Chimera Pharma S.L.U
    Inventors: Thomas Zürcher, Juan José Bernal, Cayetano von Kobbe, Ignacio Jiménez Torres, Ana Diaz Blázquez, Diana Martin Lorenzo, Gloria Calderita Lucas, Arcadio Garcia de Castro
  • VACCINES FOR THE TREATMENT OF NEOPLASIAS FROM VIRAL CAPSIDS OF BIRNAVIRUS CONTAINING ANTIGENS OF THE HUMAN PAPILLOMAVIRUS
    Publication number: 20120269844
    Abstract: The invention relates to therapeutic vaccines for the treatment of neoplasias caused by the human papillomavirus (HPV). In particular, the vaccines of the present invention are formed by chimeric virus-like capsids of birnavirus containing papillomavirus antigens.
    Type: Application
    Filed: November 5, 2010
    Publication date: October 25, 2012
    Applicant: Chimera Pharma, S.L.U.
    Inventors: Thomas Zurcher, Cayetano Von Kobbe, Juan J. Bernal, Ignacio Jiménez Torres, Gloria Calderita Lucas, Margarita Rodriguez Garcia, Ana Garzon Gutierrez, Virginia Gondar Sousa E Silva, Arcadio Garcia De Castro, Irene Pino De La Huerga
  • CHIMERIC FUSION PROTEINS AND VIRUS LIKE PARTICLES FROM BIRNAVIRUS VP2
    Publication number: 20110190164
    Abstract: The field of the invention refers to chimeric Virus Like Particles (VLP) derived from Birnavirus chimeric VP2 protein. In particular, the invention refers to chimeric VP2 fusion proteins which incorporate insertions and/or substitutions with one or more amino acids or particular peptide of interest while maintaining the capacity to assemble in the form of VLP. The invention identifies particular insertion and/or substitutions sites within VP2 P loop regions and outside said P loop regions. The invention also incorporates methods for the identification of preferred insertion and substitution sites within VP2 for the incorporation of particular amino acids and peptides of interest. The resulting chimeric VLP are of interest in the design of therapeutic and prophylactic vaccines as well as in the design of drug delivery systems, carriers for DNA and RNA in gene therapy, as targeted agents, in the development of antitoxins, and as diagnostic reagents.
    Type: Application
    Filed: May 9, 2008
    Publication date: August 4, 2011
    Inventors: Thomas Zurcher, Juan Jose Bernal, Cayetano von Kobbe, Ignacio JimenezTorres, Ana Diaz Blázquez, Diana Martin Lorenzo, Gloria Calderita Lucas, Arcadio Garcia de Castro