Patents by Inventor Ce Feng LIU

Ce Feng LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VARIANT IGF2 CONSTRUCTS
    Publication number: 20240091321
    Abstract: Provided herein are novel IGF2 peptides, fusion proteins, and nucleic acid sequences encoding novel IGF2 peptides and fusion proteins for the treatment of lysorsomal storage disorders, wherein the IGF2 peptides confer enhanced properties, such as enhanced expression, secretion and cellular uptake. The constructs provided herein are useful in treating lysosomal storage disorders by both enzyme replacement therapy and gene therapy.
    Type: Application
    Filed: October 12, 2020
    Publication date: March 21, 2024
    Applicant: Amicus Therapeutics, Inc.
    Inventors: Hung V. Do, Steven Tuske, Russell Gotschall, Ce Feng Liu
  • GENE THERAPY CONSTRUCTS AND METHODS OF USE
    Publication number: 20230233711
    Abstract: Provided herein are improved gene therapy vectors and methods of use, in some embodiments, comprising sequences for improved expression and cellular targeting of a therapeutic protein.
    Type: Application
    Filed: November 7, 2022
    Publication date: July 27, 2023
    Applicant: Amicus Therapeutics, Inc.
    Inventors: Hung V. Do, Steven Tuske, Russell Gotschall, Ce Feng Liu
  • Gene therapy constructs and methods of use
    Patent number: 11491243
    Abstract: Provided herein are improved gene therapy vectors and methods of use, in some embodiments, comprising sequences for improved expression and cellular targeting of a therapeutic protein.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: November 8, 2022
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Hung Do, Steven Tuske, Russell Gotschall, Ce Feng Liu
  • DISULFIDE BOND STABILIZED POLYPEPTIDE COMPOSITIONS AND METHODS OF USE
    Publication number: 20220023443
    Abstract: Provided herein are polypeptides comprising one or more non-native cysteine residues that form a disulfide bridge between non-native cysteines within the protein or between non-native cysteines of two monomers of the protein. Such modified human polypeptides are useful in treatment of genetic diseases via enzyme replacement therapy and/or gene therapy.
    Type: Application
    Filed: June 30, 2021
    Publication date: January 27, 2022
    Applicant: Amicus Therapeutics, Inc.
    Inventors: Hung Do, Ce Feng Liu
  • Disulfide bond stabilized polypeptide compositions and methods of use
    Patent number: 11097015
    Abstract: Provided herein are polypeptides comprising one or more non-native cysteine residues that form a disulfide bridge between non-native cysteines within the protein or between non-native cysteines of two monomers of the protein. Such modified human polypeptides are useful in treatment of genetic diseases via enzyme replacement therapy and/or gene therapy.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: August 24, 2021
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Hung Do, Ce Feng Liu
  • GENE THERAPY CONSTRUCTS AND METHODS OF USE
    Publication number: 20210162075
    Abstract: Provided herein are improved gene therapy vectors and methods of use, in some embodiments, comprising sequences for improved expression and cellular targeting of a therapeutic protein.
    Type: Application
    Filed: December 18, 2020
    Publication date: June 3, 2021
    Applicant: Amicus Therapeutics, Inc.
    Inventors: Hung Do, Steven Tuske, Russell Gotschall, Ce Feng Liu
  • Gene therapy constructs and methods of use
    Patent number: 10874750
    Abstract: Provided herein are improved gene therapy vectors and methods of use, in some embodiments, comprising sequences for improved expression and cellular targeting of a therapeutic protein.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: December 29, 2020
    Assignee: Amicus Therapeutics, Inc.
    Inventors: Hung Do, Steven Tuske, Russell Gotschall, Ce Feng Liu
  • DISULFIDE BOND STABILIZED POLYPEPTIDE COMPOSITIONS AND METHODS OF USE
    Publication number: 20200147241
    Abstract: Provided herein are polypeptides comprising one or more non-native cysteine residues that form a disulfide bridge between non-native cysteines within the protein or between non-native cysteines of two monomers of the protein. Such modified human polypeptides are useful in treatment of genetic diseases via enzyme replacement therapy and/or gene therapy.
    Type: Application
    Filed: October 10, 2019
    Publication date: May 14, 2020
    Inventors: Hung DO, Ce Feng LIU
  • GENE THERAPY CONSTRUCTS AND METHODS OF USE
    Publication number: 20190343968
    Abstract: Provided herein are improved gene therapy vectors and methods of use, in some embodiments, comprising sequences for improved expression and cellular targeting of a therapeutic protein.
    Type: Application
    Filed: April 30, 2019
    Publication date: November 14, 2019
    Inventors: Hung DO, Steven TUSKE, Russell GOTSCHALL, Ce Feng LIU