Abstract: An optimization method for capturing proteins by multi-column continuous chromatography (MCC), including the following steps: step 1, under the conditions of a set loading protein concentration and an arbitrary load residence time, performing a single time of protein breakthrough experiment to obtain a protein breakthrough curve; step 2, under a set breakthrough percentage for a target protein, integrating the breakthrough curve to obtain a single-column loading capacity and establishing a linear relationship between the interconnected load time and the load residence time; step 3, solving for the optimal number of operating columns for capturing proteins by MCC based on step 2; step 4, solving for the optimal load residence time for capturing proteins by MCC based on step 2, step 3; and step 5, solving for the maximum productivity of capturing proteins by MCC based on step 4.

Abstract: At least one embodiment of the present disclosure provides an oxide thin film transistor, a display device, and a preparation method of the oxide thin film transistor, and the oxide thin film transistor includes a base substrate; an oxide semiconductor layer provided on the base substrate, and an insulating layer provided on a side of the oxide semiconductor layer away from the base substrate; in which the insulating layer is made of oxide; the insulating layer includes a first insulating layer and a second insulating layer which are stacked; a density of the second insulating layer is greater than a density of the first insulating layer; and the second insulating layer is farther away from the base substrate than the first insulating layer.

Abstract: A method of forming a metal oxide/reduced graphene oxide composite film may be provided. The method may include providing a graphene oxide dispersion. The providing a graphene oxide dispersion method may also include adding a metal oxide to the graphene oxide dispersion to form a metal oxide/graphene oxide dispersion. The method may additionally include forming a metal oxide/graphene oxide film by filtering the metal oxide/graphene oxide dispersion using a directional flow directed assembly. The method may further include reducing the metal oxide/graphene oxide film using a reducing agent to form the metal oxide/reduced graphene oxide composite film.

Abstract: The present invention provides a directory replacement method and device. An HA receives a data access request including a first address from a first CA, if a designated storage where a directory is located is entirely occupied by the directory, and a first directory entry corresponding to the first address is not in the directory, the HA selects a second directory entry from the directory, deletes it and adds the first directory entry into the directory; before the HA replaces the directory entry in the directory, no matter what status (for example, I status, S status or A status) a share status of a cache line corresponding to an address in the directory entry to be replaced is, the HA does not need to request a corresponding CA to perform an invalidating operation on data, but directly replaces the directory entry in the directory, thereby improving replacement efficiency.

Abstract: A method of forming a metal oxide/reduced graphene oxide composite film may be provided. The method may include providing a graphene oxide dispersion. The providing a graphene oxide dispersion method may also include adding a metal oxide to the graphene oxide dispersion to form a metal oxide/graphene oxide dispersion. The method may additionally include forming a metal oxide/graphene oxide film by filtering the metal oxide/graphene oxide dispersion using a directional flow directed assembly. The method may further include reducing the metal oxide/graphene oxide film using a reducing agent to form the metal oxide/reduced graphene oxide composite film.