Patents by Inventor Cecile Jacovetti

Cecile Jacovetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for measuring NMU and for treatment using anti-NMU agents
    Patent number: 10822409
    Abstract: The inventors have produced two high specificity and high affinity monoclonal antibodies that bind to human neuromedin U (NMU). Methods and compositions are provided for treating an individual in need thereof (e.g., an individual who is obese and/or has diabetes) by administering an anti-NMU/NMUR agent (e.g., an anti-NMU antibody). For example, methods and compositions are provided for increasing circulating insulin in an individual. Methods and compositions are also provided for detecting neuromedin U (NMU) (e.g., in a biological sample such as serum). Methods and compositions are also provided for predicting whether an individual will develop diabetes and/or PDAC, and for identifying an individual who would benefit from administration of an anti-NMU/NMUR agent.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: November 3, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Seung K. Kim, Sangbin Park, Ronald Alfa, Cecile Jacovetti
  • COMPOSITIONS AND METHODS FOR MEASURING NMU AND FOR TREATMENT USING ANTI-NMU AGENTS
    Publication number: 20190218286
    Abstract: The inventors have produced two high specificity and high affinity monoclonal antibodies that bind to human neuromedin U (NMU). Methods and compositions are provided for treating an individual in need thereof (e.g., an individual who is obese and/or has diabetes) by administering an anti-NMU/NMUR agent (e.g., an anti-NMU antibody). For example, methods and compositions are provided for increasing circulating insulin in an individual. Methods and compositions are also provided for detecting neuromedin U (NMU) (e.g., in a biological sample such as serum). Methods and compositions are also provided for predicting whether an individual will develop diabetes and/or PDAC, and for identifying an individual who would benefit from administration of an anti-NMU/NMUR agent.
    Type: Application
    Filed: March 6, 2019
    Publication date: July 18, 2019
    Inventors: Seung K. Kim, Sangbin Park, Ronald Alfa, Cecile Jacovetti
  • Methods for treatment using anti-NMU agents
    Patent number: 10294297
    Abstract: The inventors have produced two high specificity and high affinity monoclonal antibodies that bind to human neuromedin U (NMU). Methods and compositions are provided for treating an individual in need thereof (e.g., an individual who is obese and/or has diabetes) by administering an anti-NMU/NMUR agent (e.g., an anti-NMU antibody). For example, methods and compositions are provided for increasing circulating insulin in an individual. Methods and compositions are also provided for detecting neuromedin U (NMU) (e.g., in a biological sample such as serum). Methods and compositions are also provided for predicting whether an individual will develop diabetes and/or PDAC, and for identifying an individual who would benefit from administration of an anti-NMU/NMUR agent.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: May 21, 2019
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Seung K. Kim, Sangbin Park, Ronald Alfa, Cecile Jacovetti
  • COMPOSITIONS AND METHODS FOR MEASURING NMU AND FOR TREATMENT USING ANTI-NMU AGENTS
    Publication number: 20170218064
    Abstract: The inventors have produced two high specificity and high affinity monoclonal antibodies that bind to human neuromedin U (NMU). Methods and compositions are provided for treating an individual in need thereof (e.g., an individual who is obese and/or has diabetes) by administering an anti-NMU/NMUR agent (e.g., an anti-NMU antibody). For example, methods and compositions are provided for increasing circulating insulin in an individual. Methods and compositions are also provided for detecting neuromedin U (NMU) (e.g., in a biological sample such as serum). Methods and compositions are also provided for predicting whether an individual will develop diabetes and/or PDAC, and for identifying an individual who would benefit from administration of an anti-NMU/NMUR agent.
    Type: Application
    Filed: January 27, 2017
    Publication date: August 3, 2017
    Inventors: Seung K. Kim, Sangbin Park, Ronald Alfa, Cecile Jacovetti