Patents by Inventor Cecilia Ann-Christin Malmborg Hanger

Cecilia Ann-Christin Malmborg Hanger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutants of interleukin-1 receptor antagonist
    Patent number: 9163072
    Abstract: The invention provides an isolated polypeptide comprising a variant amino acid sequence of SEQ ID NO: 1, or a fusion or derivative of said polypeptide, or a fusion of a said derivative thereof, wherein the polypeptide, fusion or derivative retains a biological activity of wild type IL-IRa. In one embodiment, the isolated polypeptide, fusion or derivative is or comprises a polypeptide variant of amino acid sequence SEQ ID NO: 1 comprising or consisting of substitutions at one or more of the following amino acid mutations of SEQ ID NO: 1: Q29K, P38Y, P38R, L42W, D47N, E52R, H54R, E90Y, Q129L, Q129N, M136N, M136D and Q149K. Also provided are pharmaceutical compositions of the above polypeptide, fusion or derivative, as well as uses of the same for treating a disease or condition capable of being treated by an agent which inhibits the function of IL-1 receptors.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: October 20, 2015
    Assignee: Alligator Bioscience AB
    Inventors: Eva Maria Dahlén, Karin Elisabeth Brachan, Patrick Thomas Höjman, Cecilia Ann-Christin Malmborg Hanger, Marie Asa Ingegerd Karlsson, Mats Peter Anderson, Björn Ulrik Walse
  • MUTANTS OF INTERLEUKIN- 1 RECEPTOR ANTAGONIST AND USES THEREOF
    Publication number: 20130129672
    Abstract: The invention provides an isolated polypeptide comprising a variant amino acid sequence of SEQ ID NO: 1, or a fusion or derivative of said polypeptide, or a fusion of a said derivative thereof, wherein the polypeptide, fusion or derivative retains a biological activity of wild type IL-IRa. In one embodiment, the isolated polypeptide, fusion or derivative is or comprises a polypeptide variant of amino acid sequence SEQ ID NO: 1 comprising or consisting of substitutions at one or more of the following amino acid mutations of SEQ ID NO: 1: Q29K, P38Y, P38R, L42W, D47N, E52R, H54R, E90Y, Q129L, Q129N, M136N, M136D and Q149K. Also provided are pharmaceutical compositions of the above polypeptide, fusion or derivative, as well as uses of the same for treating a disease or condition capable of being treated by an agent which inhibits the function of IL-1 receptors.
    Type: Application
    Filed: July 10, 2012
    Publication date: May 23, 2013
    Applicant: Alligator Bioscience AB
    Inventors: Eva Maria DAHLÉN, Karin Elisabeth Brachan, Patrick Thomas Höjman, Cecilia Ann-Christin Malmborg Hanger, Marie Asa Ingegerd Karlsson, Mats Peter Anderson, Björn Ulrik Walse