Patents by Inventor Cecilia Subauste

Cecilia Subauste has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating CD40-mediated diseases
    Patent number: 12319726
    Abstract: A cell-permeable polypeptide includes a membrane transduction domain and a polypeptide comprising an amino acid sequence substantially homologous to the amino acid sequence of the TRAF2,3 binding domain, the cell permeable peptide inhibiting binding of TRAF2 to the TRAF2,3 binding domain of CD40 to decrease or inhibit a CD-40 activity or signal transduction pathway associated with a CD40-mediated disease in cells of a subject.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: June 3, 2025
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Carlos Subauste, Cecilia Subauste
  • METHOD FOR TREATING CD40-MEDIATED DISEASES
    Publication number: 20200308252
    Abstract: A cell-permeable polypeptide includes a membrane transduction domain and a polypeptide comprising an amino acid sequence substantially homologous to the amino acid sequence of the TRAF2,3 binding domain, the cell permeable peptide inhibiting binding of TRAF2 to the TRAF2,3 binding domain of CD40 to decrease or inhibit a CD-40 activity or signal transduction pathway associated with a CD40-mediated disease in cells of a subject.
    Type: Application
    Filed: June 2, 2020
    Publication date: October 1, 2020
    Inventors: Carlos Subauste, Cecilia Subauste
  • Method for treating CD40-mediated diseases
    Patent number: 10669345
    Abstract: A cell-permeable polypeptide includes a membrane transduction domain and a polypeptide comprising an amino acid sequence substantially homologous to the amino acid sequence of the TRAF2,3 binding domain, the cell permeable peptide inhibiting binding of TRAF2 to the TRAF2,3 binding domain of CD40 to decrease or inhibit a CD-40 activity or signal transduction pathway associated with a CD40-mediated disease in cells of a subject.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: June 2, 2020
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Carlos Subauste, Cecilia Subauste
  • METHOD FOR TREATING CD40-MEDIATED DISEASES
    Publication number: 20170051070
    Abstract: A cell-permeable polypeptide includes a membrane transduction domain and a polypeptide comprising an amino acid sequence substantially homologous to the amino acid sequence of the TRAF2,3 binding domain, the cell permeable peptide inhibiting binding of TRAF2 to the TRAF2,3 binding domain of CD40 to decrease or inhibit a CD-40 activity or signal transduction pathway associated with a CD40-mediated disease in cells of a subject.
    Type: Application
    Filed: November 8, 2016
    Publication date: February 23, 2017
    Inventors: Carlos Subauste, Cecilia Subauste
  • Method of treating CD40-mediated diseases
    Patent number: 9486498
    Abstract: A method for treating a CD40-mediated disease in a subject includes administering to cells expressing CD40 of the subject a therapeutically effective amount of an agent that inhibits binding of TNF receptor associated factor 2 (TRAF2) to a cytoplasmic portion of CD40.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: November 8, 2016
    Assignee: Case Western Reserve University
    Inventors: Carlos Subauste, Cecilia Subauste