Abstract: A process for continuous preparation of halogenated alkoxyethane of general formula XClHC—CF2OR, where X is —Cl or —F and OR is C1-4 alkoxy, the process comprising a step of introducing in a flow reactor reaction components comprising (i) a compound of general formula XClC?CF2, (ii) abase, and (iii) a C1-4 alkanol, wherein a) the flow reactor comprises one or more tubular flow line(s) having an internal cross-sectional area of less than 115 mm2 through which the reaction components flow as a reaction mixture, and b) the halogenated alkoxyethane is formed at least upon the reaction components mixing, with the so formed halogenated alkoxyethane flowing out of the flow reactor in a reactor effluent.

Abstract: A process for continuous preparation of halogenated alkoxyethane of general formula XClHC—CF2OR, where X is —Cl or -f and OR is C1-4 alkoxy, the process comprising a step of introducing in a flow reactor reaction components comprising (i) a compound of general formula XClHC—CYF2, where each of X and Y is independently —Cl or —F, (ii) a base, and (iii) a C1-4 alkanol, wherein a) the flow reactor comprises one or more tubular flow line(s) through which the reaction components flow as a reaction mixture, c) the halogenated alkoxyethane is formed at least upon the reaction components mixing, with the so formed halogenated alkoxyethane flowing out of the flow reactor in a reactor effluent, and b) the base is one that forms a salt soluble in the alkanol during formation of the halogenated alkoxyethane.