Patents by Inventor Cedric Pearce

Cedric Pearce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SEMI-SYNTHETIC ANALOGUES OF EPIPOLYTHIODIOXOPIPERAZINE ALKALOIDS
    Publication number: 20220235072
    Abstract: Disclosed herein are compounds, compositions, and methods for inhibiting a histone methyltransferase. The compounds are verticillin derivatives that exhibit anti-proliferative activity against cancer cells. The compounds, compositions, and methods can be used to treat a subject with cancer.
    Type: Application
    Filed: May 22, 2020
    Publication date: July 28, 2022
    Inventors: James Robert FUCHS, Andrew HUNTSMAN, Nicholas Hunter OBERLIES, Chiraz Soumia AMRINE, Huzefa RAJA, Joanna BURDETTE, Cedric PEARCE
  • Methods and Compositions for the Inhibition of Quorum Sensing in Bacterial Infections
    Publication number: 20200289611
    Abstract: This disclosure is directed to novel apicidin methods and compositions for the inhibition of quorum sensing in bacterial infections and novel apicidin methods and compositions for treating a staphylococcal infection.
    Type: Application
    Filed: May 12, 2017
    Publication date: September 17, 2020
    Inventors: Nicholas Oberlies, Cedric Pearce, Alexander Horswill, Jeffrey Kavanaugh, Corey Parlet, Tamam El-Elimat
  • Non-aromatic difluoro analogues of resorcylic acid lactones
    Patent number: 10632099
    Abstract: This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aromatic difluoro analogues of resorcylic acid lactones.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: April 28, 2020
    Assignee: University of North Carolina at Greensboro
    Inventors: Mitchell P. Croatt, Lara Fakhouri, Nicholas H. Oberlies, Cedric Pearce
  • Non-Aromatic Difluoro Analogues of Resorcylic Acid Lactones
    Publication number: 20190381002
    Abstract: This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aromatic difluoro analogues of resorcylic acid lactones.
    Type: Application
    Filed: August 30, 2019
    Publication date: December 19, 2019
    Inventors: Mitchell P. Croatt, Lara Fakhouri, Nicholas H. Oberlies, Cedric Pearce
  • Non-aromatic difluoro analogues of resorcylic acid lactones
    Patent number: 10434085
    Abstract: This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aromatic difluoro analogues of resorcylic acid lactones.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: October 8, 2019
    Assignee: University of North Carolina at Greensboro
    Inventors: Mitchell P. Croatt, Lara Fakhouri, Nicholas H. Oberlies, Cedric Pearce
  • NON-AROMATIC DIFLUORO ANALOGUES OF RESORCYLIC ACID LACTONES
    Publication number: 20180153854
    Abstract: This disclosure is directed to non-aromatic difluoro analogues of resorcylic acid lactones, pharmaceutical compositions comprising non-aromatic difluoro analogues of resorcylic acid lactones, and methods of treatment comprising non-aromatic difluoro analogues of resorcylic acid lactones.
    Type: Application
    Filed: May 27, 2016
    Publication date: June 7, 2018
    Inventors: Mitchell P. Croatt, Lara Fakhouri, Nicholas H. Oberlies, Cedric Pearce