Patents by Inventor Celia Kingsbury

Celia Kingsbury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRROLO[2,3-d]PYRIMIDIN-2-YL-AMINE DERIVATIVES AS PKC-THETA INHIBITORS
    Publication number: 20110218189
    Abstract: The present invention relates to a pyrrolo[2,3-d]pyrimidin-2-yl-amine derivative according to formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising one or more of said pyrrolo[2,3-d]pyrimidine-2-ylamine derivatives and to their use in therapy, for instance in the treatment of PKC? mediated disorders.
    Type: Application
    Filed: April 8, 2009
    Publication date: September 8, 2011
    Applicant: N.V. ORGANON
    Inventors: Andrew Laird Roughton, Koc-kan Ho, Michael Ohlmeyer, David Diller, Irina Neagu, Celia Kingsbury, Jui-Hsiang Chan, Johannes Petrus, Mmaria Lommerse, Neeltje Miranda Teerhuis, Jacobus Comelis Henricus Maria Wijkmans, Ralf Plate
  • Compounds with medicinal effects due to interaction with the glucocorticoid receptor
    Patent number: 7960365
    Abstract: The invention provides for compounds having the structure according to the formula I wherein: X is a carbon or nitrogen atom; Ar is phenyl or heteroaromatic ring; R1 is hydrogen, halogen, CN or (1C-4C)alkyl; R2 is hydrogen, halogen or optionally fluorinated (1C-3C)alkoxy; R3 and R5 are independently hydrogen, optionally halogenated (1C-4C)alkyl, optionally halogenated (1C-4C)alkoxy, optionally halogenated aryl(1C-4C)alkoxy, optionally halogenated (1C-4C)alkenyl or hydroxylmethyl; R4 is hydrogen, halogen, optionally halogenated (1C-4C)alkoxy or optionally halogenated aryl(1C-4C)alkoxy; R6 is hydrogen, benzyl, optionally substituted with one or more halogens or (1C-4C)alkyl, or R6 is optionally halogenated (1C-4C)alkyl; each R7 independently is hydrogen, halogen, optionally halogenated (1C-4C)alkyl or optionally halogenated (1C-4C)alkoxy and pharmaceutically suitable acid addition salts thereof for use as glucocorticoid receptor modulators, in particular for treatment of central nervous system disorders.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: June 14, 2011
    Assignee: N.V. Organon
    Inventors: Niall Morton Hamilton, Simon James Anthony Grove, Michael John Kiczun, John Richard Morphy, Brad Sherborne, Peter Thomas Albert Littlewood, Angus Richard Brown, Celia Kingsbury, Michael Ohhlmeyer, Koc-Kan Ho, Steven G. Kultgen
  • 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
    Patent number: 7919490
    Abstract: The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: April 5, 2011
    Assignee: Wyeth LLC
    Inventors: Irina Neagu, David Diller, Celia Kingsbury, Adolph C. Bohnstedt, Michael J. Ohlmeyer, Vidyadhar Paradkar, Nasrin Ansari
  • 8-substituted 2-(benzimidazolyl)purine derivatives for immunosuppression
    Patent number: 7915268
    Abstract: The present invention provides novel purines useful for the prevention and treatment of autoimmune diseases, inflammatory diseases, mast cell mediated disease and transplant rejection.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: March 29, 2011
    Assignee: Wyeth LLC
    Inventors: Yingchun Lu, Celia Kingsbury, Adolph Bohnstedt, Michael Ohlmeyer, Vidyadhar Paradkar
  • 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
    Patent number: 7902187
    Abstract: The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Grant
    Filed: August 22, 2008
    Date of Patent: March 8, 2011
    Assignee: Wyeth LLC
    Inventors: Irina Neagu, David Diller, Celia Kingsbury, Adolph C. Bohnstedt, Michael J. Ohlmeyer, Vidyadhar Paradkar, Nasrin Ansari
  • PURINES AS PKC-THETA INHIBITORS
    Publication number: 20110046131
    Abstract: A chemical genus of purines, which are useful as PKC? inhibitors, is disclosed.
    Type: Application
    Filed: October 19, 2007
    Publication date: February 24, 2011
    Inventors: Irina Neagu, Andrew Laird Roughton, Koc-Kan Ho, David Diller, Jui-Hsiang Chan, Michael Ohlmeyer, Celia Kingsbury, Johannes Petrus Maria Lommerse, Neeltje Miranda, Jacobus Cornelis Henricus Maria Wijkmans
  • Purine and imidazopyridine derivatives for immunosuppression
    Patent number: 7884109
    Abstract: The present invention provides novel purine and imidazopyridine derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Grant
    Filed: October 11, 2007
    Date of Patent: February 8, 2011
    Assignee: Wyeth LLC
    Inventors: Michael J. Ohlmeyer, Adolph C. Bohnstedt, Celia Kingsbury, Koc-Kan Ho, Jorge Gabriel Quintero, Ming You, Haengsoon Park, Yingchun Lu
  • 6-SUBSTITUTED 2-(BENZIMIDAZOLYL)PURINE AND PURINONE DERIVATIVES FOR IMMUNOSUPPRESSION
    Publication number: 20090069289
    Abstract: The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Application
    Filed: August 22, 2008
    Publication date: March 12, 2009
    Applicant: PHARMACOPEIA, INC.
    Inventors: Irina Neagu, David Diller, Celia Kingsbury, Adolph C. Bohnstedt, Michael J. Ohlmeyer, Vidyadhar Paradkar, Ansari Nasrin
  • PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION
    Publication number: 20080287468
    Abstract: The present invention provides novel purine and imidazopyridine derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Application
    Filed: October 11, 2007
    Publication date: November 20, 2008
    Applicant: PHARMACOPEIA, INC.
    Inventors: Michael J. Ohlmeyer, Adolph C. Bohnstedt, Celia Kingsbury, Koc-Kan Ho, Jorge Gabriel Quintero, Ming You, Haengsoon Park, Yingchun Lu
  • 6-SUBSTITUTED 2-(BENZIMIDAZOLYL)PURINE AND PURINONE DERIVATIVES FOR IMMUNOSUPPRESSION
    Publication number: 20080214580
    Abstract: The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Application
    Filed: October 4, 2007
    Publication date: September 4, 2008
    Applicant: PHARMACOPEIA, INC.
    Inventors: Irina Neagu, David Diller, Celia Kingsbury, Adolph C. Bohnstedt, Michael J. Ohlmeyer, Vidyadhar Paradkar, Nasrin Ansari
  • 7-Substituted Purine Derivatives for Immunosuppression
    Publication number: 20080119496
    Abstract: The present invention provides novel purinone and related derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Application
    Filed: November 16, 2006
    Publication date: May 22, 2008
    Applicant: PHARMACOPEIA DRUG DISCOVERY, INC.
    Inventors: Michael J. Ohlmeyer, Adolph Bohnstedt, Celia Kingsbury, Koc-Kan Ho, Jorge Quintero
  • 8-SUBSTITUTED 2-(BENZIMIDAZOLYL)PURINE DERIVATIVES FOR IMMUNOSUPPRESSION
    Publication number: 20080085898
    Abstract: The present invention provides novel purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Application
    Filed: October 4, 2007
    Publication date: April 10, 2008
    Applicant: PHARMACOPEIA, INC.
    Inventors: Yingchun Lu, Celia Kingsbury, Adolph Bohnstedt, Michael Ohlmeyer, Vidyadhar Paradkar
  • Compounds with medicinal effects due to interaction with the glucocorticoid receptor
    Publication number: 20070149577
    Abstract: The invention provides for compounds having the structure according to the formula I wherein: X is a carbon or nitrogen atom; Ar is phenyl or heteroaromatic ring; R1 is hydrogen, halogen, CN or (1C-4C)alkyl; R2 is hydrogen, halogen or optionally fluorinated (1C-3C)alkoxy; R3 and R5 are independently hydrogen, optionally halogenated (1C-4C)alkyl, optionally halogenated (1C-4C)alkoxy, optionally halogenated aryl(1C-4C)alkoxy, optionally halogenated (1C-4C)alkenyl or hydroxylmethyl; R4 is hydrogen, halogen, optionally halogenated (1C-4C)alkoxy or optionally halogenated aryl(1C-4C)alkoxy; R6 is hydrogen, benzyl, optionally substituted with one or more halogens or (1C-4C)alkyl, or R6 is optionally halogenated (1C-4C)alkyl; each R7 independently is hydrogen, halogen, optionally halogenated (1C-4C)alkyl or optionally halogenated (1C-4C)alkoxy and pharmaceutically suitable acid addition salts thereof for use as glucocorticoid receptor modulators, in particular for treatment of central nervous system disorders.
    Type: Application
    Filed: December 19, 2006
    Publication date: June 28, 2007
    Applicants: N.V. Organon, Pharmacopeia Drug Discovery Inc.
    Inventors: Niall Hamilton, Simon Grove, Michael Kiczun, John Morphy, Brad Sherborne, Peter Littlewood, Angus Brown, Celia Kingsbury, Michael Ohlmeyer, Koc-Kan Ho, Steven Kultgen
  • Purine and imidazopyridine derivatives for immunosuppression
    Publication number: 20070021443
    Abstract: The present invention provides novel purine and imidazopyridine derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection.
    Type: Application
    Filed: April 5, 2006
    Publication date: January 25, 2007
    Inventors: Michael Ohlmeyer, Adolph Bohnstedt, Celia Kingsbury, Koc-Kan Ho, Jorge Quintero, Ming You, Haengsoon Park, Yingchun Lu