Patents by Inventor Celine ViAROUGE

Celine ViAROUGE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of retinyl esters
    Patent number: 11905542
    Abstract: The present invention is related to a novel enzymatic process for production of retinyl esters, such as in particular retinyl long chain esters, via conversion of retinol, which process includes the use of enzymes having acyltransferase activity. Said process might be used for biotechnological production of vitamin A.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: February 20, 2024
    Assignee: DSM IP ASSETS B.V.
    Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge
  • BIOSYNTHESIS OF RETINOIDS
    Publication number: 20230227862
    Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.
    Type: Application
    Filed: January 30, 2023
    Publication date: July 20, 2023
    Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
  • Biosynthesis of retinoids
    Patent number: 11578344
    Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: February 14, 2023
    Assignee: DSM IP ASSETS B.V.
    Inventors: Nathalie Balch, Paul Blomquist, Reed Doten, Peter Houston, Ethan Lam, Jenna McMahon, Joshua Trueheart, Celine Viarouge
  • Microbial production of nicotamide riboside
    Patent number: 10913965
    Abstract: The present disclosure relates to a novel method, expression vectors, and host cells for producing nicotinamide riboside by regulating the pathways that lead to the production of nicotinamide riboside.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: February 9, 2021
    Assignee: DSM IP ASSETS B.V.
    Inventors: Adam G. Lawrence, Celine ViArouge
  • MICROBIAL PRODUCTION OF NICOTINAMIDE RIBOSIDE
    Publication number: 20200362381
    Abstract: The present invention is directed to microbial production of nicotinamide mononucleotide using a genetically modified fungus.
    Type: Application
    Filed: May 17, 2018
    Publication date: November 19, 2020
    Inventors: Adam LAWRENCE, Celine VIAROUGE
  • PRODUCTION OF TRANS-RETINAL
    Publication number: 20200277644
    Abstract: The present invention is related to a novel enzymatic process for production of vitamin A aldehyde (retinal) via stereoselective conversion of beta-carotene which process includes the use of trans-selective enzymes having activity as beta-carotene oxidases (BCOs), in particular having preference for trans-retinal. 5 Said process is in particular useful for biotechnological production of vitamin A.
    Type: Application
    Filed: September 25, 2018
    Publication date: September 3, 2020
    Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE, René Marcel DE JONG
  • MICROBIAL PRODUCTION OF NICOTINAMIDE RIBOSIDE
    Publication number: 20200255877
    Abstract: The present invention is directed to microbial production of nicotinamide riboside and/or nicotinamide mononucleotide using a genetically modified fungus.
    Type: Application
    Filed: May 17, 2018
    Publication date: August 13, 2020
    Inventors: Adam LAWRENCE, Celine VIAROUGE
  • PRODUCTION OF RETINOL
    Publication number: 20200248151
    Abstract: The present invention is related to a novel enzymatic process for production of vitamin A alcohol (retinol) via conversion of retinal, which process includes the use of heterologous enzymes having activity as retinal reductase, particularly wherein the reaction leads to at least about 90% conversion of retinal into retinol. Said process is particularly useful for biotechnological production of vitamin A.
    Type: Application
    Filed: September 25, 2018
    Publication date: August 6, 2020
    Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
  • PRODUCTION OF RETINYL ESTERS
    Publication number: 20200239924
    Abstract: The present invention is related to a novel enzymatic process for production of retinyl esters, such as in particular retinyl long chain esters, via conversion of retinol, which process includes the use of enzymes having acyltransferase activity. Said process might be used for biotechnological production of vitamin A.
    Type: Application
    Filed: September 25, 2018
    Publication date: July 30, 2020
    Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
  • PRODUCTION OF RETINYL ESTERS
    Publication number: 20200239925
    Abstract: The present invention is related to production of retinyl esters, such as in particular retinyl acetate, an important building block for production of vitamin A. The retinyl esters might be generated via enzymatic conversion of retinol which process includes the use of enzymes with acetyl-transferase (ATF) activity, thus acetylating retinol into retinol/retinyl acetate. Said process is particularly useful for biotechnological production of vitamin A.
    Type: Application
    Filed: September 25, 2018
    Publication date: July 30, 2020
    Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE, René Marcel DE JONG
  • BIOSYNTHESIS OF RETINOIDS
    Publication number: 20200231993
    Abstract: The present invention is related to a novel enzymatic process for production of retinoids via a multi-step process, which process includes the use of heterologous enzymes having activity in a carotene-producing host cell, particularly wherein such process results in high percentage of retinoids, in trans-isoform.
    Type: Application
    Filed: September 25, 2018
    Publication date: July 23, 2020
    Inventors: Nathalie BALCH, Paul BLOMQUIST, Reed DOTEN, Peter HOUSTON, Ethan LAM, Jenna MCMAHON, Joshua TRUEHEART, Celine VIAROUGE
  • MICROBIAL PRODUCTION OF NICOTINIC ACID RIBOSIDE
    Publication number: 20190071680
    Abstract: The present invention relates to a novel method, expression vectors, and host cells for producing nicotinic acid riboside by regulating the pathways that lead to the production of nicotinic acid riboside.
    Type: Application
    Filed: March 16, 2017
    Publication date: March 7, 2019
    Inventors: Adam G. LAWRENCE, Celine VIAROUGE
  • MICROBIAL PRODUCTION OF NICOTAMIDE RIBOSIDE
    Publication number: 20180327797
    Abstract: The present disclosure relates to a novel method, expression vectors, and host cells for producing nicotinamide riboside by regulating the pathways that lead to the production of nicotinamide riboside.
    Type: Application
    Filed: November 14, 2016
    Publication date: November 15, 2018
    Inventors: Adam G. LAWRENCE, Celine ViAROUGE