Patents by Inventor Celso Miguel Sandoval Rodríguez

Celso Miguel Sandoval Rodríguez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTERMEDIATES FOR THE PREPARATION OF 11-METHYLENE STEROIDS
    Publication number: 20210269474
    Abstract: Compounds having the formula or solvates of the compounds can be used as intermediates in the preparation of the synthetic steroids, Etonogestrel and Desogestrel, as well as other pharmaceutically active agents.
    Type: Application
    Filed: May 13, 2021
    Publication date: September 2, 2021
    Inventors: Celso Miguel SANDOVAL RODRÍGUEZ, Ignacio HERRÁIZ SIERRA, lvano MESSINA, Jesús Miguel IGLESIAS RETUERTO
  • Process and new intermediates for the preparation of 11-methylene steroids
    Patent number: 11034716
    Abstract: A process for the preparation of 11-methylene steroids from di-keto steroids involves selective olefination of the ketone at position 11 of the di-keto steroids. The resulting 11-methylene steroid products can be used as intermediates in the preparation of the synthetic steroids, Etonogestrel and Desogestrel, as well as other pharmaceutically active agents.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: June 15, 2021
    Assignee: CRYSTAL PHARMA, S.A.U.
    Inventors: Celso Miguel Sandoval Rodríguez, Ignacio Herráiz Sierra, Ivano Messina, Jesús Miguel Iglesias Retuerto
  • PROCESS AND NEW INTERMEDIATES FOR THE PREPARATION OF 11-METHYLENE STEROIDS
    Publication number: 20190092807
    Abstract: The invention relates to a process for the preparation of 11-methylene steroids through selective olefination of the ketone at position 11. The resulting products are useful intermediates in the preparation of several pharmaceutically active agents, such as Etonogestrel and Desogestrel.
    Type: Application
    Filed: March 2, 2017
    Publication date: March 28, 2019
    Inventors: Celso Miguel SANDOVAL RODRÍGUEZ, Ignacio HERRÁIZ SIERRA, lvano MESSINA, Jesús Miguel IGLESIAS RETUERTO
  • Process for alkynylating 16-substituted-17-keto steroids
    Patent number: 9296780
    Abstract: A process ethynylates 16-methylene-17-keto steroids to the corresponding 16-methylene-17?-ethynyl-17?-hydroxy steroids by treatment with silyl-protected lithium acetylides followed by further desilylation. The resulting products are useful intermediates in the preparation of several pharmaceutically active agents, such as e.g. Nestorone® or melengestrol acetate.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: March 29, 2016
    Assignees: Crystal Pharma, S.A.U., Population Council Inc.
    Inventors: Luis Gerardo Gutiérrez Fuentes, Celso Miguel Sandoval Rodriguez
  • PROCESS FOR ALKYNYLATING 16-SUBSTITUTED-17-KETO STEROIDS
    Publication number: 20150005518
    Abstract: A process ethynylates 16-methylene-17-keto steroids to the corresponding 16-methylene-17?-ethynyl-17?-hydroxy steroids by treatment with silyl-protected lithium acetylides followed by further desilylation. The resulting products are useful intermediates in the preparation of several pharmaceutically active agents, such as e.g. Nestorone® or melengestrol acetate.
    Type: Application
    Filed: December 19, 2012
    Publication date: January 1, 2015
    Applicants: CRYSTAL PHARMA, S.A.U., THE POPULATION COUNCIL INC.
    Inventors: Luis Gerardo Gutiérrez Fuentes, Celso Miguel Sandoval Rodríguez
  • SYNTHESIS OF ABIRATERONE AND RELATED COMPOUNDS
    Publication number: 20140011992
    Abstract: The present invention relates to processes for obtaining abiraterone and derivatives thereof, such as abiraterone acetate, by means of a Suzuki coupling through a steroid borate of general formula (IV) or a C—C coupling through a steroid hydrazone of general formula (II), as well as to intermediates useful in said processes.
    Type: Application
    Filed: December 20, 2012
    Publication date: January 9, 2014
    Applicant: CRYSTAL PHARMA, S.A.U.
    Inventors: Alfonso Perez Encabo, Jose Angel Turiel Hernandez, Francisco Javier Gallo Nieto, Antonio Lorente Bonde-Larsen, Celso Miguel Sandoval Rodriguez