Abstract: In one of many possible embodiments, a system is provided for modeling telecommunication switch investments. The exemplary system includes a telecommunication switch modeling application configured to determine equipment quantities having capacity to satisfy switch design parameters descriptive of at least one model telecommunication switch, and calculate model investments associated with the equipment quantities. The exemplary system also includes a telecommunication switch investment modeling application configured to weight the model investments in accordance with at least one of a network parameter descriptive of an actual telecommunication switch and a “what-if” input descriptive of a hypothetical telecommunication switch configuration to form weighted investments that are specific to at least one of the actual telecommunication switch and the hypothetical telecommunication switch configuration.

Abstract: In one of many possible embodiments, a system is provided for modeling telecommunication switch investments. The exemplary system includes a telecommunication switch modeling application configured to determine equipment quantities having capacity to satisfy switch design parameters descriptive of at least one model telecommunication switch, and calculate model investments associated with the equipment quantities. The exemplary system also includes a telecommunication switch investment modeling application configured to weight the model investments in accordance with at least one of a network parameter descriptive of an actual telecommunication switch and a “what-if” input descriptive of a hypothetical telecommunication switch configuration to form weighted investments that are specific to at least one of the actual telecommunication switch and the hypothetical telecommunication switch configuration.

Abstract: In one of many possible embodiments, a system is provided for modeling telecommunication switch investments. The exemplary system includes a telecommunication switch modeling application configured to determine equipment quantities having capacity to satisfy switch design parameters descriptive of at least one model telecommunication switch, and calculate model investments associated with the equipment quantities. The exemplary system also includes a telecommunication switch investment modeling application configured to weight the model investments in accordance with at least one of a network parameter descriptive of an actual telecommunication switch and a “what-if” input descriptive of a hypothetical telecommunication switch configuration to form weighted investments that are specific to at least one of the actual telecommunication switch and the hypothetical telecommunication switch configuration.

Abstract: Hepatocyte culturing system, primer sets and an analytical method for selectively detecting and quantitatively assessing the levels of mRNA expression of the major isoenzymes of cytochrome P450 (CYP450 1A1, 1A2, 2B1/2, 2C11, 2E1, 3A1, 3A2 and 4A1), fatty acyl-CoA oxidase (FACO) and select Phase II conjugating enzymes (UDPGT, GST and ST) in the rat using specific 5′ and 3′ oligonucleotide primers and reverse transcriptase-polymerase chain reaction. The method closely reproduces the expression obtained from rat liver tissue following treatment with the same enzyme inducers. Constitutive and inducible expression was maintained by resuspending, culturing and then overlaying adult rat hepatocytes with an extracellular matrix such as Matrigel®.

Abstract: Hepatocyte culturing system, primer sets and an analytical method for selectively detecting and quantitatively assessing the levels of mRNA expression of the major isoenzymes of cytochrome P450 (CYP450 1A1, 1A2, 2B1/2, 2C11, 2E1, 3A1, 3A2 and 4A1), fatty acyl-CoA oxidase (FACO) and select Phase II conjugating enzymes (UDPGT, GST and ST) in the rat using specific 5' and 3' oligonucleotide primers and reverse transcriptase-polymerase chain reaction. The method closely reproduces the expression obtained from rat liver tissue following treatment with the same enzyme inducers. Constitutive and inducible expression was maintained by resuspending, culturing and then overlaying adult rat hepatocytes with an extracellular matrix such as Matrigel.RTM..