Patents by Inventor Cesar Labarca

Cesar Labarca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Point mutant mice with hypersensitive alpha 4 nicotinic receptors: dopaminergic pathology and increased anxiety
    Patent number: 6753456
    Abstract: The present invention relates to transgenic animals expressing a hypersensitive nicotinic acetylcholine receptor. Transgenic animals have point mutations in the nucleic acid sequence encoding the &agr;4 subunit of the receptor that result in increased sensitivity to nicotine. Such transgenic animals are model systems for nicotine addiction and certain types of epilepsy.
    Type: Grant
    Filed: September 7, 2001
    Date of Patent: June 22, 2004
    Assignee: California Institute of Technology
    Inventors: Henry A. Lester, Cesar Labarca, Johannes Schwarz, Carlos Fonck
  • Point mutant mice with hypersensitive alpha 4 nicotinic receptors: dompaminergic pathology and increased anxiety
    Publication number: 20020104107
    Abstract: The present invention relates to transgenic animals expressing a hypersensitive nicotinic acetylcholine receptor. Transgenic animals have point mutations in the nucleic acid sequence encoding the &agr;4 subunit of the receptor that result in increased sensitivity to nicotine. Such transgenic animals are model systems for nicotine addiction and certain types of epilepsy.
    Type: Application
    Filed: September 7, 2001
    Publication date: August 1, 2002
    Inventors: Henry A. Lester, Cesar Labarca, Johannes Schwarz, Carlos Fonck