Abstract: A pH sensor comprises: a chamber for receiving an electrolyte solution; a first and a second ion-sensitive field effect transistor (ISFETs), each of the first and second ISFETs having a source terminal, a drain terminal and a transistor channel extending between the source terminal and the drain terminal, a dielectric layer with a sensing surface arranged in the chamber so as to be contactable by the electrolyte solution, the dielectric layer separating the sensing surface from the transistor channel; a first measurement circuit configured to measure a first source-drain resistance across the transistor channel of the first ISFET; and a second measurement circuit configured to measure a second source-drain resistance across the transistor channel of the second ISFET. The first and second measurement circuits include a common reference electrode, the reference electrode arranged contactable by the electrolyte solution in the chamber.

Abstract: A pH sensor comprises: a chamber for receiving an electrolyte solution; a first and a second ion-sensitive field effect transistor (ISFETs), each of the first and second ISFETs having a source terminal, a drain terminal and a transistor channel extending between the source terminal and the drain terminal, a dielectric layer with a sensing surface arranged in the chamber so as to be contactable by the electrolyte solution, the dielectric layer separating the sensing surface from the transistor channel; a first measurement circuit configured to measure a first source-drain resistance across the transistor channel of the first ISFET; and a second measurement circuit configured to measure a second source-drain resistance across the transistor channel of the second ISFET. The first and second measurement circuits include a common reference electrode, the reference electrode arranged contactable by the electrolyte solution in the chamber.

Abstract: An ISFET or ISFET-based sensor includes a source terminal, a drain terminal and a transistor channel between the source terminal and the drain terminal, where the ISFET or ISFET-based sensor also includes a fin extending between the source terminal and the drain terminal, the fin including the transistor channel, the fin having opposite sides with charge-sensitive surface for forming an interface with an analyte solution and an insulating barrier between the charge-sensitive surface and the transistor channel located centrally between the opposite sides of the fin, such that the transistor channel has a height-to-width ratio of at least 10.

Abstract: The present invention is related to an electrochemical reactor (1) and a microfluidic platform (20) comprising this reactor (1), controlling pH in a closed environment, wherein this reactor (1) comprises at least one cell (2), wherein each cell (2) containing at least one micro-well (3a) able to contain a liquid and reagents and a cap (7) to close the said cell (2) and wherein the cell (2) further comprises at least one working electrode (5) producing reversible REDOX reactions.

Abstract: The present invention is related to an electrochemical reactor (1) and a microfluidic platform (20) comprising this reactor (1), controlling pH in a closed environment, wherein this reactor (1) comprises at least one cell (2), wherein each cell (2) containing at least one micro-well (3a) able to contain a liquid and reagents and a cap (7) to close the said cell (2) and wherein the cell (2) further comprises at least one working electrode (5) producing reversible REDOX reactions.