Abstract: A receiver applies a calibration method to compensate for skew between input channels. The receiver skew is estimated by observing the coefficients of an adaptive equalizer which adjusts the coefficients based on time-varying properties of the multi-channel input signal. The receiver skew is compensated by programming the phase of the sampling clocks for the different channels. Furthermore, during real-time operation of the receiver, channel diagnostics is performed to automatically estimate differential group delay and/or other channel characteristics based on the equalizer coefficients using a frequency averaging or polarization averaging approach. Framer information can furthermore be utilized to estimate differential group delay that is an integer multiple of the symbol rate. Additionally, a DSP reset may be performed when substantial signal degradation is detected based on the channel diagnostics information.

Abstract: Methods and apparatus for a seal according to various aspects of the present invention include a seal operating in conjunction with a housing and a removable cover. A portion of the seal is attached to the housing and another portion of the seal is attached to the removable cover to enclose a joint between the housing and the removable cover. A cutter cuts the seal, which allows the removable cover to be removed.

Abstract: Glycosylated indolocarbazoles, method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates to the methods used to obtain the recombinant strains and the production of rebeccamycin and staurosporine derivatives. The invention also relates to bacterial strains that are of use for the production of rebeccamycin and staurosporine derivatives. Lastly, the rebeccamycin and staurosporine derivatives described herein are applicable to the field of human health, specifically for manufacturing drugs that are of use in the treatment of tumour, neurological and inflammatory diseases.

Abstract: A multi-caliber fuze kit includes a fuze housing configured for coupling with multiple projectiles. One or more canards are moveably coupled with the fuze housing. The one or more canards are adjustable between two or more canard configurations. In a first canard configuration, the one or more canards are at a first canard angle relative to a bore sight of the fuze housing, and the first canard angle is configured for use with a first projectile. In a second canard configuration, the one or more canards are at a second canard angle relative to the bore sight of the fuze housing, and the second canard angle is configured for use with a second projectile. The first and second canard angles are different. In another example, in the first canard configuration the one or more canards include a first canard shape configured to provide a first specified trajectory with the first projectile.

Abstract: A multi-caliber fuze kit includes a fuze housing configured for coupling with multiple projectiles. One or more canards are moveably coupled with the fuze housing. The one or more canards are adjustable between two or more canard configurations. In a first canard configuration, the one or more canards are at a first canard angle relative to a bore sight of the fuze housing, and the first canard angle is configured for use with a first projectile. In a second canard configuration, the one or more canards are at a second canard angle relative to the bore sight of the fuze housing, and the second canard angle is configured for use with a second projectile. The first and second canard angles are different. In another example, in the first canard configuration the one or more canards include a first canard shape configured to provide a first specified trajectory with the first projectile.

Abstract: Method for production of indolocarbazoles by using rebeccamycin biosynthetic genes. The invention is based on utilization of rebeccamycin biosynthetic genes from Saccharothrix aerocolonigenes for production of indolocarbazoles in related microorganisms (Streptomyces spp.). Method includes the isolation of a DNA fragment from Saccharothrix aerocolonigenes ATCC39243 containing the rebeccamycin biosynthesis gene cluster and the expression of these genes in Streptomyces albus, achieving production of rebeccamycin and derivatives. The invention is suitable for use in the pharmaceutical field.

Abstract: A fuze guidance system is configurable by an end user, allowing the end user to select between different configurations of canards of the system. The different configurations of canards may include canards with different surface areas, optimized for providing appropriate control with different sizes of munitions. The different configurations may be accomplished by having canards with separable portions which may be broken off or otherwise removed by the end user, to reduce canard surface area and/or span. Alternatively the fuze guidance system may come in a kit with multiple sets of canards having different sizes or otherwise having different configurations for providing different aerodynamic characteristics. The end user may select a canard set based on the munition size or type that the fuze guidance system is to be used with.

Abstract: Glycosylated indolocarbazoles, method for obtaining same and uses thereof. This invention relates to rebeccamycin and staurosporine derivatives obtained by fermentation of recombinant bacterial strains. The invention also relates to the methods used to obtain the recombinant strains and the production of rebeccamycin and staurosporine derivatives. The invention also relates to bacterial strains that are of use for the production of rebeccamycin and staurosporine derivatives. Lastly, the rebeccamycin and staurosporine derivatives described herein are applicable to the field of human health, specifically for manufacturing drugs that are of use in the treatment of tumour, neurological and inflammatory diseases.

Abstract: A projectile fuze sends a signal having encoded telemetry data. The telemetry data may be encoded by modulating an aspect or characteristic of the signal, such as frequency modulation of the signal. The fuze may receive and interpret reflections in order to determine proximity to a target or other object, such as by functioning as a height of burst sensor. The signal may include a series of random or seemingly random pulses (a keyed pattern of pulses), such as pulses in amplitude of the signal. The fuze includes a pair of transceivers for sending signals of different frequencies through an antenna, and for receiving signals through the antenna. The transceivers are configured such that one or the other is used at any one time when telemetry data is sent, with telemetry being encoded by changes in frequencies.

Abstract: A smart fuze system includes a radome used to hold a replaceable smart fuze module in place. An internally-threaded collar screws onto threads on the main body of the smart fuze system. Pressure from the radome presses the smart fuze module against electrical connections in the main body. The smart fuze module may thereby be held in place without potting material, allowing different types of fuzes to be swapped into place. The different types of fuzes may include a type that communicates height of burst (HOB) information a type that communicates telemetry, and a type that communicates both HOB and telemetry information.

Abstract: A projectile fuze sends a signal having encoded telemetry data. The telemetry data may be encoded by modulating an aspect or characteristic of the signal, such as frequency modulation of the signal. The fuze may receive and interpret reflections in order to determine proximity to a target or other object, such as by functioning as a height of burst sensor. The signal may include a series of random or seemingly random pulses (a keyed pattern of pulses), such as pulses in amplitude of the signal. The fuze includes a pair of transceivers for sending signals of different frequencies through an antenna, and for receiving signals through the antenna. The transceivers are configured such that one or the other is used at any one time when telemetry data is sent, with telemetry being encoded by changes in frequencies.

Abstract: A smart fuze system includes a radome used to hold a replaceable smart fuze module in place. An internally-threaded collar screws onto threads on the main body of the smart fuze system. Pressure from the radome presses the smart fuze module against electrical connections in the main body. The smart fuze module may thereby be held in place without potting material, allowing different types of fuzes to be swapped into place. The different types of fuzes may include a type that communicates height of burst (HOB) information a type that communicates telemetry, and a type that communicates both HOB and telemetry information.

Abstract: A fuze guidance system is configurable by an end user, allowing the end user to select between different configurations of canards of the system. The different configurations of canards may include canards with different surface areas, optimized for providing appropriate control with different sizes of munitions. The different configurations may be accomplished by having canards with separable portions which may be broken off or otherwise removed by the end user, to reduce canard surface area and/or span. Alternatively the fuze guidance system may come in a kit with multiple sets of canards having different sizes or otherwise having different configurations for providing different aerodynamic characteristics. The end user may select a canard set based on the munition size or type that the fuze guidance system is to be used with.

Abstract: The present invention relates to the biosynthesis of polyketides and derives from the cloning of nucleic acids encoding a polyketide synthase and other associated proteins involved in the synthesis of the polyketide borrelidin. Materials and Methods including enzyme systems, nucleic acids, vectors and cells are provided for the preparation of polyketides including borrelidin and analogues and derivatives thereof. Novel polyketide molecules are also provided.

Abstract: The present invention relates to the biosynthesis of polyketides and derives from the cloning of nucleic acids encoding a polyketide synthase and other associated proteins involved in the synthesis of the polyketide borrelidin. Materials and methods including enzyme systems, nucleic acids, vectors and cells are provided for the preparation of polyketides including borrelidin and analogues and derivatives thereof. Novel polyketide molecules are also provided.

Abstract: Methods and apparatus for a seal according to various aspects of the present invention include a seal operating in conjunction with a housing and a removable cover. A portion of the seal is attached to the housing and another portion of the seal is attached to the removable cover to enclose a joint between the housing and the removable cover. A cutter cuts the seal, which allows the removable cover to be removed.

Abstract: Method for production of indolocarbazoles by using rebeccamycin biosynthetic genes. The invention is based on utilization of rebeccamycin biosynthetic genes from Saccharothrix aerocolonigenes for production of indolocarbazoles in related microorganisms (Streptomyces spp.). Method includes the isolation of a DNA fragment from Saccharothrix aerocolonigenes ATCC39243 containing the rebeccamycin biosynthesis gene cluster and the expression of these genes in Streptomyces albus, achieving production of rebeccamycin and derivatives. The invention is suitable for use in the pharmaceutical field.

Abstract: This invention provides detailed sequence analysis and characterization of the gene cluster responsible for the synthesis of bleomycin in Streptomyces verticillus. The bleomycin gene cluster provides the first hybrid polyketide synthase/nonribosomal peptide synthetase pathway and elucidation of the various modules and enzymatic domains characterizing the pathway provides convenient synthetic routes for bleomycins, bleomycin analogs, and various other polyketides.

Abstract: A system and method for reducing acquisition times in a GPS receiver enables determination at start-up of the GPS receiver of the occurrence of ephemeris data at the GPS receiver being older than approximately two hours or a change in a mobile country code and mobile network code of a cellular device associated with the GPS receiver. Data is obtained for the GPS receiver from a reference server responsive to occurrence of one of these conditions and the position of the GPS receiver is determined at a reduced acquisition time using the obtained data.